Zobrazeno 1 - 3
of 3
pro vyhledávání: '"P. C. Lyden"'
Autor:
Daniela Bezdan, Kirill Grigorev, Cem Meydan, Fanny A. Pelissier Vatter, Michele Cioffi, Varsha Rao, Matthew MacKay, Kiichi Nakahira, Philip Burnham, Ebrahim Afshinnekoo, Craig Westover, Daniel Butler, Chris Mozsary, Timothy Donahoe, Jonathan Foox, Tejaswini Mishra, Serena Lucotti, Brinda K. Rana, Ari M. Melnick, Haiying Zhang, Irina Matei, David Kelsen, Kenneth Yu, David C. Lyden, Lynn Taylor, Susan M. Bailey, Michael P. Snyder, Francine E. Garrett-Bakelman, Stephan Ossowski, Iwijn De Vlaminck, Christopher E. Mason
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101844- (2020)
Summary: Liquid biopsies based on cell-free DNA (cfDNA) or exosomes provide a noninvasive approach to monitor human health and disease but have not been utilized for astronauts. Here, we profile cfDNA characteristics, including fragment size, cellula
Externí odkaz:
https://doaj.org/article/03949e9af66945e29ccf6aa8c8313a46
Autor:
Oren J Becher, Nathan E Millard, Shakeel Modak, Brian H Kushner, Sofia Haque, Ivan Spasojevic, Tanya M Trippett, Stephen W Gilheeney, Yasmin Khakoo, David C Lyden, Kevin C De Braganca, Jill M Kolesar, Jason T Huse, Kim Kramer, Nai-Kong V Cheung, Ira J Dunkel
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178593 (2017)
The PI3K/Akt/mTOR signaling pathway is aberrantly activated in various pediatric tumors. We conducted a phase I study of the Akt inhibitor perifosine in patients with recurrent/refractory pediatric CNS and solid tumors. This was a standard 3+3 open-l
Externí odkaz:
https://doaj.org/article/2b51ab3280554c088f6a1fb5944b499a
Autor:
E. C. Haley, C. A. Lewandowski, John R. Marler, T. G. Brott, M. Lu, J. C. Grotta, P. C. Lyden, Joseph P. Broderick, S. H. Horowitz, T. P. Kwiatkowski, B. C. Tilley, Steven R. Levine, M. P. Frankel
Publikováno v:
Neurology. 55:1649-1655
Background: The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study showed a similar percentage of intracranial hemorrhage and good outcome in patients 3 months after stroke treatment given 0 to 90 minutes and 91 to 180