Zobrazeno 1 - 10
of 66
pro vyhledávání: '"P. C. ISAKSON"'
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 5, Pp 357-362 (1993)
The present investigation characterizes calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis in the rat. Intraperitoneal injection of A-23187 (20 μg/rat) stimulated marked biosynthesis of 6-keto-PGF1α (6-KPA), TxB2, LTC4 and LTB4,
Externí odkaz:
https://doaj.org/article/940d75287b6a44e3907c42513a3888cc
Publikováno v:
The Journal of Neuroscience. 21:5847-5853
Western blots show the constitutive expression of COX-1 and COX-2 in the rat spinal dorsal and ventral horns and in the dorsal root ganglia. Using selective inhibitors of cyclooxygenase (COX) isozymes, we show that in rats with chronic indwelling int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae3435b24239b0368154ad2b9c7919b
https://doi.org/10.1523/jneurosci.21-16-05847.2001
https://doi.org/10.1523/jneurosci.21-16-05847.2001
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(3)
Interleukin-4 was one of the first cytokines to be intensively studied and remains one of the most interesting and biologically important ([1][1]). It has a distinctive spectrum of biological activities, many of which are unique to IL-4 or to both IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9f3adf2acfd78dc8c08d5f03b412d4
https://pubmed.ncbi.nlm.nih.gov/23335801
https://pubmed.ncbi.nlm.nih.gov/23335801
Autor:
David W. Goodman, P C Isakson
Publikováno v:
Journal of Biological Chemistry. 268:4207-4215
Mitogen activation of resting lymphocytes induces expression of high affinity insulin receptors on the plasma membrane. The mechanism underlying this effect on insulin receptor expression was examined by comparing levels of insulin receptor mRNA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::147b4d70a8ff1f0f77602bc4fa7a72e0
https://doi.org/10.1016/s0021-9258(18)53598-5
https://doi.org/10.1016/s0021-9258(18)53598-5
Autor:
David B. Reitz, Timothy S. Chamberlain, P. C. Isakson, Karen Seibert, H.‐C. Huang, Carol M. Koboldt
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43444b5d74cbd16b4ebfd5b1f3803e07
https://doi.org/10.1002/chin.199608116
https://doi.org/10.1002/chin.199608116
Autor:
T. D. PENNING, S. W. KRAMER, L. F. LEE, P. W. COLLINS, C. M. KOBOLDT, K. SEIBERT, A. W. VEENHUIZEN, Y. Y. ZHANG, P. C. ISAKSON
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f82e82eff202864a178478e8f1481bb5
https://doi.org/10.1002/chin.199751139
https://doi.org/10.1002/chin.199751139
Publikováno v:
The Journal of Immunology. 148:934-942
The expression of c-myb mRNA is differentially regulated in murine B lymphoid tumors such that B cell lymphomas and plasmacytomas contain significantly less c-myb mRNA than pre-B cell lymphomas. To examine the low level of c-myb mRNA expression in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab30110117385ba14b22dd80574663b
https://doi.org/10.4049/jimmunol.148.3.934
https://doi.org/10.4049/jimmunol.148.3.934
Publikováno v:
Advances in experimental medicine and biology. 469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c161f484c59411d7d96c0cf7bf840aa0
https://pubmed.ncbi.nlm.nih.gov/10667326
https://pubmed.ncbi.nlm.nih.gov/10667326
Autor:
L S, Simon, F L, Lanza, P E, Lipsky, R C, Hubbard, S, Talwalker, B D, Schwartz, P C, Isakson, G S, Geis
Publikováno v:
Arthritis and rheumatism. 41(9)
To investigate the efficacy and safety of SC-58635 (celecoxib), an antiinflammatory and analgesic agent that acts by selective cyclooxygenase 2 (COX-2) inhibition and is not expected to cause the typical gastrointestinal (GI), renal, and platelet-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0473c58b1313485456689eb236a89989
https://pubmed.ncbi.nlm.nih.gov/9751091
https://pubmed.ncbi.nlm.nih.gov/9751091
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
Intrathecal administration of nonsteroidal anti-inflammatory drugs in the rat blocks the thermal hyperalgesia induced by tissue injury, which suggests a role for spinal cyclooxygenase (COX) products in this facilitated state. Two isozymes of the COX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::337d906abf0d47d1b79a124ca3c8aae8
https://pubmed.ncbi.nlm.nih.gov/9618405
https://pubmed.ncbi.nlm.nih.gov/9618405