Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P. C. Bradshaw"'
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Protein disulfide isomerase A3 (PDIA3, also named GRP58, ER-60, ERp57) is conserved across species and mediates protein folding in the endoplasmic reticulum. PDIA3 is, reportedly, a chaperone for STAT3. However, the role of PDIA3
Externí odkaz:
https://doaj.org/article/73494cbfd41c4b538b0788c82236cd74
Autor:
S. Paradis, J. Tiano, E. De Borger, A. Pusceddu, C. Bradshaw, C. Ennas, C. Morys, M. Sciberras
Publikováno v:
Earth System Science Data, Vol 16, Pp 3547-3563 (2024)
Marine sediments are among the largest carbon reservoirs on the planet and play a key role in the global cycling of organic matter. Bottom fisheries are the most widespread anthropogenic physical disturbance to seabed habitats, prompting NGOs and gov
Externí odkaz:
https://doaj.org/article/ac74c55387824ba38944d4ede30e64a7
Publikováno v:
Clinical Practice and Cases in Emergency Medicine, Vol 7, Iss 4, Pp 215-220 (2023)
Introduction: Spontaneous coronary artery dissection (SCAD) is a rare cause of myocardial infarction. Patients suffering SCAD are often young women without typical risk factors for atherosclerotic heart disease. Clinicians should maintain a high inde
Externí odkaz:
https://doaj.org/article/9abfbc5be5c54c439be1a989635e1758
Autor:
Leah E. Jamerson, Patrick C. Bradshaw
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 820 (2024)
Dietary restriction (DR) protocols frequently employ intermittent fasting. Following a period of fasting, meal consumption increases lipogenic gene expression, including that of NADPH-generating enzymes that fuel lipogenesis in white adipose tissue (
Externí odkaz:
https://doaj.org/article/0ccf9556ad514f598e55b80c1f18c08c
Autor:
Ryan B. Shartau, Lenora D. M. Turcotte, Julia C. Bradshaw, Andrew R. S. Ross, Blair D. Surridge, Nina Nemcek, Stewart C. Johnson
Publikováno v:
Toxins, Vol 15, Iss 6, p 395 (2023)
Harmful algal blooms (HABs) in coastal British Columbia (BC), Canada, negatively impact the salmon aquaculture industry. One disease of interest to salmon aquaculture is Net Pen Liver Disease (NPLD), which induces severe liver damage and is believed
Externí odkaz:
https://doaj.org/article/3faa57464b6947f785f22dd9f589d192
Publikováno v:
Fishes, Vol 8, Iss 5, p 252 (2023)
Piscine orthoreovirus genotype 1 (PRV-1) is an endemic virus to the Northeastern Pacific that infects both wild and farmed salmon. To better understand PRV-1 prevalence and transmission pathways in the region, we targeted out-migrating juvenile Pacif
Externí odkaz:
https://doaj.org/article/aa81f8f81c92489887f6c9ff821e6983
Publikováno v:
Cells, Vol 11, Iss 15, p 2416 (2022)
Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of Parkinson’s disease (PD). The improper selection of mitochondria for mitophagy increases reactive oxygen species (ROS) levels and lowers ATP levels. The downstre
Externí odkaz:
https://doaj.org/article/3089985697734174b96bcbda9e88d0c3
Autor:
Darrell Sawmiller, Song Li, Takashi Mori, Ahsan Habib, David Rongo, Vedad Delic, Patrick C. Bradshaw, R. Douglas Shytle, Cyndy Sanberg, Paula Bickford, Jun Tan
Publikováno v:
Heliyon, Vol 3, Iss 4, Pp e00279- (2017)
Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is linked to oxidative stress, altered amyloid precursor protein (APP) proteolysis, tau hyperphosphorylation and the accumulation of amyloid-β (Aβ) plaques and neurofibrillary ta
Externí odkaz:
https://doaj.org/article/32c10e694e194585868a8d388edaac80
Autor:
Kyle A Garver, Stewart C Johnson, Mark P Polinski, Julia C Bradshaw, Gary D Marty, Heindrich N Snyman, Diane B Morrison, Jon Richard
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146229 (2016)
Heart and skeletal muscle inflammation (HSMI) is a significant and often fatal disease of cultured Atlantic salmon in Norway. The consistent presence of Piscine orthoreovirus (PRV) in HSMI diseased fish along with the correlation of viral load and an
Externí odkaz:
https://doaj.org/article/19ef70e83a104b4ab05999a9e32f1c14
Autor:
Andrew H. Baker, Alan L. Parker, Angela C. Bradshaw, Stuart A. Nicklin, Iain A. McNeish, Raul Alba, Lynda Coughlan
Publikováno v:
Viruses, Vol 2, Iss 10, Pp 2290-2355 (2010)
Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to
Externí odkaz:
https://doaj.org/article/259cc6d4ac4c4da5a391f457b3764772