Zobrazeno 1 - 10
of 1 763
pro vyhledávání: '"P. C. Thomas"'
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background CRISPR-Cas9 technology has revolutionised genetic screens and can inform on gene essentiality and chemo-genetic interactions. It is easily deployed and widely supported with many pooled CRISPR libraries available commercially. How
Externí odkaz:
https://doaj.org/article/574ca2d4911c473bb792ac54e36683cb
Autor:
Zachary Van Roy, Prabakar Arumugam, Blake P. Bertrand, Dhananjay D. Shinde, Vinai C. Thomas, Tammy Kielian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Infection is a devastating post-surgical complication, often requiring additional procedures and prolonged antibiotic therapy. This is especially relevant for craniotomy and prosthetic joint infections (PJI), both of which are characterized
Externí odkaz:
https://doaj.org/article/b9cb3c1ff84d4d3fa443a10ad71a822a
Autor:
Jenna M. Schulz, Trevor B. Birmingham, Holly T. Philpott, C. Thomas Appleton, Hayden F. Atkinson, J. Robert Giffin, Frank Beier
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Mechanobiological mechanisms of osteoarthritis (OA) are unclear. Our objectives were to explore: 1) changes in knee joint physiology using a large panel of synovial fluid biomarkers from before to one year after high tibial osteot
Externí odkaz:
https://doaj.org/article/8c23195c0cdf4b74b9cc97da6115444d
Autor:
Yiyuan Li, Gregg W. C. Thomas, Stephen Richards, Robert M. Waterhouse, Xin Zhou, Michael E. Pfrender
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Mitochondrial genes and nuclear genes cooperate closely to maintain the functions of mitochondria, especially in the oxidative phosphorylation (OXPHOS) pathway. However, mitochondrial genes among arthropod lineages have dramatic e
Externí odkaz:
https://doaj.org/article/084615316c774349b0836ac9dda48c96
Autor:
Catherine C. Thomas, Michael C. Schwalbe, Macario Garcia, Geoffrey L. Cohen, Hazel Rose Markus
Publikováno v:
RSF: The Russell Sage Foundation Journal of the Social Sciences, Vol 10, Iss 4, Pp 60-83 (2024)
We investigate the contrasting realities of the pandemic on psychosocial experiences and ways of coping among American Voices Project respondent surveys (N = 720) and interviews (N = 172). Despite similar levels of distress early in the pandemic, by
Externí odkaz:
https://doaj.org/article/a806da2df65045fab42433bf67bcec07
Autor:
James C. Thomas, Gavin D. Lukasik, Felix A. Rodriguez, Waruna D. Kulatilaka, Eric L. Petersen
Publikováno v:
FirePhysChem, Vol 4, Iss 3, Pp 252-263 (2024)
Metal fuels, such as aluminum (Al) and iron (Fe), can be added to composite solid propellants to improve their performance, such as specific impulse, density, and burning rate. In comparison to aluminum, iron can theoretically provide improved densit
Externí odkaz:
https://doaj.org/article/ee68be5c35e3431f850e8431f370c71f
Autor:
Vaishnavi Prabhakar, N. Rajvikram, Umamaheshwari Ramachandran, R. Saravanan, Abraham Anandapandian Ponsekar, Davis C. Thomas
Publikováno v:
The Journal of Indian Prosthodontic Society, Vol 24, Iss 3, Pp 284-291 (2024)
Aim: Temporomandibular disorders (TMD) comprise ailments involving the jaw joint (temporomandibular joint) and its associated anatomical structures. The complexity involved in TMD is primarily due to its broad spectrum of conditions, clinical signs a
Externí odkaz:
https://doaj.org/article/5a89360287c2458a9c3d6edb4bb66ed1
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract A major challenge in Parkinson’s disease is the variability in symptoms and rates of progression, underpinned by heterogeneity of pathological processes. Biomarkers are urgently needed for accurate diagnosis, patient stratification, monito
Externí odkaz:
https://doaj.org/article/56d26ae0f17c4578a79ad029f1f39b87
Autor:
Hyunseung Jung, Igal Brener, Sadhvikas J. Addamane, Ting Shan Luk, C. Thomas Harris, Ganapathi Subramania, Oleg Mitrofanov
Publikováno v:
Advanced Photonics Research, Vol 5, Iss 12, Pp n/a-n/a (2024)
Metasurfaces have opened doors to combining multiple photonic functionalities in a single compact device. In particular, the ability to generate short terahertz (THz) pulses with precise wavefront engineering in a single THz metasurface redefined the
Externí odkaz:
https://doaj.org/article/1fe64cd8840246beb2b23411145b3120
Autor:
Alissa J. Cooper, MD, Natasha Rekhtman, MD, PhD, Marina K. Baine, MD, PhD, Marie C. Thomas, DNP, FNP-C, Alia C. Lynch, PharmD, BCOP, Ryan D. Gentzler, MD, MS
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100750- (2024)
Tarlatamab, a DLL3-targeting bispecific T-cell engager, has rapidly assumed the role of a new standard of care in the later-line treatment of extensive-stage SCLC. Little is known about the efficacy of tarlatamab in other histologies such as DLL3-exp
Externí odkaz:
https://doaj.org/article/a8288d90bce449ed811d1abf0dde896c