Zobrazeno 1 - 10
of 1 565
pro vyhledávání: '"P. Billingham"'
Autor:
Joshua L. Katz, Yuheng Geng, Leah K. Billingham, Nishanth S. Sadagopan, Susan L. DeLay, Jay Subbiah, Tzu-yi Chia, Graysen McManus, Chao Wei, Hanxiang Wang, Hanchen Lin, Caylee Silvers, Lauren K. Boland, Si Wang, Hanxiao Wan, David Hou, Gustavo Ignacio Vázquez-Cervantes, Tarlan Arjmandi, Zainab H. Shaikh, Peng Zhang, Atique U. Ahmed, Deanna M. Tiek, Catalina Lee-Chang, Edward T. Chouchani, Jason Miska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Glioblastoma is a Grade 4 primary brain tumor defined by therapy resistance, diffuse infiltration, and near-uniform lethality. The underlying mechanisms are unknown, and no treatment has been curative. Using a recently developed creatine kin
Externí odkaz:
https://doaj.org/article/dd7a023fe4514c80a5ab446bc7743f92
We develop a shape-Newton method for solving generic free-boundary problems where one of the free-boundary conditions is governed by the Bernoulli equation. The Newton-like scheme is developed by employing shape derivatives in the weak forms, which a
Externí odkaz:
http://arxiv.org/abs/2305.14254
Autor:
Needham, D. J., Billingham, J.
In the second part of this series of papers, we address the same Cauchy problem that was considered in part 1, namely the nonlocal Fisher-KPP equation in one spatial dimension, \[ u_t = D u_{xx} + u(1-\phi*u), \] where $\phi*u$ is a spatial convoluti
Externí odkaz:
http://arxiv.org/abs/2304.10935
We study the Cauchy problem on the real line for the nonlocal Fisher-KPP equation in one spatial dimension, \[ u_t = D u_{xx} + u(1-\phi*u), \] where $\phi*u$ is a spatial convolution with the top hat kernel, $\phi(y) \equiv H\left(\frac{1}{4}-y^2\ri
Externí odkaz:
http://arxiv.org/abs/2304.10922
Autor:
Giancola, Silvio, Cioppa, Anthony, Georgieva, Julia, Billingham, Johsan, Serner, Andreas, Peek, Kerry, Ghanem, Bernard, Van Droogenbroeck, Marc
Association football is a complex and dynamic sport, with numerous actions occurring simultaneously in each game. Analyzing football videos is challenging and requires identifying subtle and diverse spatio-temporal patterns. Despite recent advances i
Externí odkaz:
http://arxiv.org/abs/2304.04220
Autor:
Belinda Davey, Wesley Billingham, Jacqueline Davis, Lisa Gibson, Nina D'Vaz, Susan Prescott, Desiree Silva, Sarah Whalan
Publikováno v:
International Journal of Population Data Science, Vol 8, Iss 6 (2024)
Introduction The ORIGINS Project ("ORIGINS") is a longitudinal, population-level birth cohort with data and biosample collections that aim to facilitate research to reduce non-communicable diseases (NCDs) and encourage 'a healthy start to life'. ORIG
Externí odkaz:
https://doaj.org/article/c049cb90a5124a2f886d39254d1e7446
Autor:
Fatima Khan, Yiyun Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R. Grant Rowe, Derek A. Wainwright, Kathleen McCortney, Leah K. Billingham, Jason Miska, Craig Horbinski, Maciej S. Lesniak, Peiwen Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glycolysis impairs macrophage migrat
Externí odkaz:
https://doaj.org/article/35dfc6866f9b4dd6a0d5a41599612d47
How do children with language disorder perceive their peer interactions? A qualitative investigation
Publikováno v:
Autism and Developmental Language Impairments, Vol 9 (2024)
Background and aims Peer interaction difficulties are often elevated amongst children with language disorders, yet the mechanisms underlying these difficulties are unclear. Previous research indicates that poor conflict management, social withdrawal,
Externí odkaz:
https://doaj.org/article/a94d8d62d02d4d68a4da233079587ad6
Autor:
Divyalakshmi Bhaskaran, Joshua Savage, Amit Patel, Fiona Collinson, Rhys Mant, Florien Boele, Lucy Brazil, Sara Meade, Peter Buckle, Siân Lax, Lucinda Billingham, Susan C. Short
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Glioblastoma (GBM) is the most common adult malignant brain tumour, with an incidence of 5 per 100,000 per year in England. Patients with tumours showing O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation represent
Externí odkaz:
https://doaj.org/article/eab0ef4f27614cabaf65f9eab32b4134
Autor:
Amit Patel, Kristian Brock, Daniel Slade, Claire Gaunt, Anthony Kong, Hisham Mehanna, Lucinda Billingham, Piers Gaunt
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background In this article we describe the methodology of the time-to-event continual reassessment method in the presence of partial orders (PO-TITE-CRM) and the process of implementing this trial design into a phase I trial in head and neck
Externí odkaz:
https://doaj.org/article/482169edd81b4cb08d5b3a47c93c2213