Zobrazeno 1 - 10
of 264
pro vyhledávání: '"P. Beusch"'
Autor:
Samrat Sahu, Benjamin Emenike, Christian Michel Beusch, Pritha Bagchi, David Ezra Gordon, Monika Raj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Methionine plays a critical role in various biological and cell regulatory processes, making its chemoproteomic profiling indispensable for exploring its functions and potential in protein therapeutics. Building on the principle of rapid oxi
Externí odkaz:
https://doaj.org/article/9367a00a29de43b7a5a1b24bbc7b30e5
Autor:
Ahmed Moursy, Antoine Cléry, Stefan Gerhardy, Katharina M. Betz, Sanjana Rao, Jarosław Mazur, Sébastien Campagne, Irene Beusch, Malgorzata M. Duszczyk, Mark D. Robinson, Vikram Govind Panse, Frédéric H.-T. Allain
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The conserved SR-like protein Npl3 promotes splicing of diverse pre-mRNAs. However, the RNA sequence(s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 during the splicing reaction remain elusive. Here, we developed a split-iC
Externí odkaz:
https://doaj.org/article/4a88fb1ca6af451d9d41da0376069163
Autor:
Shane C. Wright, Aikaterini Motso, Stefania Koutsilieri, Christian M. Beusch, Pierre Sabatier, Alessandro Berghella, Élodie Blondel-Tepaz, Kimberley Mangenot, Ioannis Pittarokoilis, Despoina-Christina Sismanoglou, Christian Le Gouill, Jesper V. Olsen, Roman A. Zubarev, Nevin A. Lambert, Alexander S. Hauser, Michel Bouvier, Volker M. Lauschke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract G protein-coupled receptors are important drug targets that engage and activate signaling transducers in multiple cellular compartments. Delineating therapeutic signaling from signaling associated with adverse events is an important step tow
Externí odkaz:
https://doaj.org/article/87f6a5fc98af40a19909134b0c703db6
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis
Autor:
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian M. Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M. Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I. Svensson, Hans Ulrich Scherer, René E. M. Toes, Inger Gjertsson, Olov Ekwall, Roman A. Zubarev, Rikard Holmdahl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Although elevated levels of anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA), the in vivo functions of these antibodies remain unclear. Here, we have expressed monoclonal ACPAs derived from patients w
Externí odkaz:
https://doaj.org/article/7b376f73d800450f955918dee2fa82ac
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Beate Brandl, Coline Czech, Susanne I. Wudy, Anja Beusch, Hans Hauner, Thomas Skurk, Roman Lang
Publikováno v:
Beverages, Vol 10, Iss 1, p 12 (2024)
Health-related nutritional human studies rely on the validity of dietary data provided by study participants. Reliable biomarkers for food intake help objectify data collected by food frequency questionnaires. They facilitate the monitoring of compli
Externí odkaz:
https://doaj.org/article/d1d93626efa64d4b8e1c4babe2992787
Publikováno v:
Earth System Dynamics, Vol 13, Pp 851-877 (2022)
The degree of trust placed in climate model projections is commensurate with how well their uncertainty can be quantified, particularly at timescales relevant to climate policy makers. On inter-annual to decadal timescales, model projection uncertain
Externí odkaz:
https://doaj.org/article/810d322c47394e4ba3aae8dcfbf5c373
Publikováno v:
Geoscientific Model Development, Vol 15, Pp 2085-2103 (2022)
Producing targeted climate information at the local scale, including major sources of climate change projection uncertainty for diverse emissions scenarios, is essential to support climate change mitigation and adaptation efforts. Here, we present th
Externí odkaz:
https://doaj.org/article/05f95298bf60470b8d6776b9f6b8240f