Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P. B. Mullan"'
Autor:
Charlotte Zoe Angel, Shannon Beattie, Ezanee Azlina Mohamad Hanif, Micheal P. Ryan, Francisco D. C. Guerra Liberal, Shu-Dong Zhang, Scott Monteith, Niamh E. Buckley, Emma Parker, Shannon Haynes, Alexander J. McIntyre, Paula Haddock, Madina Sharifova, Cristina M. Branco, Paul B. Mullan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Summary In our study, we focused on a particular subtype of aggressive breast cancer called Triple-Negative Breast Cancer (TNBC). We investigated a complex series of events that contribute to poor outcomes in this disease and uncovered a crucial sign
Externí odkaz:
https://doaj.org/article/50a9cdbafd634451b85b457b222534e5
Autor:
James P. Beirne, Alan Gilmore, Caitríona E. McInerney, Aideen Roddy, W. Glenn McCluggage, Ian J.G. Harley, M. Abdullah Alvi, Kevin M. Prise, Darragh G. McArt, Paul B. Mullan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3359-3371 (2022)
Introduction: Cancers presenting at advanced stages inherently have poor prognosis. High grade serous carcinoma (HGSC) is the most common and aggressive form of tubo-ovarian cancer. Clinical tests to accurately diagnose and monitor this condition are
Externí odkaz:
https://doaj.org/article/1c8bf9d25c064531ac26941f78c36845
Autor:
Paul B. Mullan, Victoria Bingham, Paula Haddock, Gareth W. Irwin, Elaine Kay, Stephen McQuaid, Niamh E. Buckley
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Triple Negative breast cancer (TNBC) is a poor outcome subgroup of breast cancer defined based on the absence of expression of ERα and PR and HER2 amplification. These hard to treat cancers lack targeted treatment options and are
Externí odkaz:
https://doaj.org/article/4531eab64b0f409585612c4bdac7b40f
Publikováno v:
MedEdPORTAL, Vol 16 (2020)
Introduction The majority of older adults with advanced dementia (AD) develop difficulties with eating and swallowing, often prompting concerns about nutrition and quality of life. Employing a palliative approach requires providers to attain skills i
Externí odkaz:
https://doaj.org/article/3e4dced757aa4a18af7420b66b8f2792
Autor:
Catherine Knowlson, Paula Haddock, Victoria Bingham, Stephen McQuaid, Paul B. Mullan, Niamh E. Buckley
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Triple negative breast cancer (TNBC) is the subset of breast cancer associated with the poorest outcome, and currently lacks targeted treatments. Standard of care (SoC) chemotherapy often consists of DNA damaging chemotherapies ± taxanes
Externí odkaz:
https://doaj.org/article/ab780ea7438942eeac9c9a303770bbce
Autor:
Thomas G. Saba, Marc B. Hershenson, Manuel Arteta, Ixsy A. Ramirez, Patricia B. Mullan, Sonal T. Owens
Publikováno v:
Medical Education Online, Vol 20, Iss 0, Pp 1-5 (2015)
Objective: Our objective was to evaluate the educational value of introducing pre-clinical medical students to pediatric patients and their families in a subspecialty clinic setting. Methods: First- and second-year medical students at the University
Externí odkaz:
https://doaj.org/article/75ae4c3a2f794ea591e80ce1c6c6acaa
Publikováno v:
Geoscientific Model Development, Vol 7, Iss 5, Pp 2359-2391 (2014)
We adapt and integrate the Biome-BGC and Land Use in Rural New Zealand models to simulate pastoral agriculture and to make land-use change, intensification of agricultural activity and climate change scenario projections of New Zealand's pasture prod
Externí odkaz:
https://doaj.org/article/7cb89a4149be44bead4b886ecca822bb
Autor:
Maya Subbarao Iyer, Patricia B. Mullan, Sally A. Santen, Athina Sikavitsas, Jennifer G. Christner
Publikováno v:
Western Journal of Emergency Medicine, Vol 15, Iss 4, Pp 1-6 (2014)
INTRODUCTION: The Pediatric Emergency Department (PED) provides medical students with learning in a high-volume, fast-paced environment; characteristics that can be stressful for new students. Shadowing can improve transitioning, yet this alone does
Externí odkaz:
https://doaj.org/article/dbd8c7b9c25149a395f66217314be469
Autor:
Win Boon, Jennifer McAllister, Mohammad A. Attar, Rachel L. Chapman, Patricia B. Mullan, Hilary M. Haftel
Publikováno v:
International Journal of Pediatrics, Vol 2014 (2014)
Objective. Accurate heart rate (HR) determination during neonatal resuscitation (NR) informs subsequent NR actions. This study’s objective was to evaluate HR determination timeliness, communication, and accuracy during high fidelity NR simulations
Externí odkaz:
https://doaj.org/article/dd8e5604753c43618fa800e874b72576
Autor:
P. B. Mullan, S. McWilliams, J. Quinn, H. Andrews, P. Gilmore, N. McCabe, S. McKenna, D. P. Harkin
Publikováno v:
Biochemical Society Transactions. 29:678-683
The introduction of microarray technology to the scientific and medical communities has dramatically changed the way in which we now address basic biomedical questions. Expression profiling using microarrays facilitates an experimental approach where