Výsledky vyhledávání

Akademický článek

Molecular profiling of microinvasive breast cancer microenvironment progression

Autor: F. Lessi, C. Scatena, P. Aretini, M. Menicagli, S. Franceschi, A. G. Naccarato, C. M. Mazzanti

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)

Abstract Background Tumors develop by progression through a series of stages. Every cell of the tumor microenvironment is constantly changing in the flow of the cancer progression. It has become clear in recent years that stroma is essential for tumo

Externí odkaz: https://doaj.org/article/3d4ac91af38c40cc93c4dd85d7fdbc91

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Whole-exome sequencing to identify causative variants in juvenile sudden cardiac death

Autor: Martina Modena, Alberto Giannoni, Alberto Aimo, Paolo Aretini, Nicoletta Botto, Simona Vittorini, Andrea Scatena, Diana Bonuccelli, Marco Di Paolo, Michele Emdin

Publikováno v: Human Genomics, Vol 18, Iss 1, Pp 1-18 (2024)

Abstract Background Juvenile sudden cardiac death (SCD) remains unexplained in approximately 40% of cases, leading to a significant emotional burden for the victims’ families and society. Comprehensive investigations are essential to uncover its el

Externí odkaz: https://doaj.org/article/cc80cff76de340ce8860c84178dcae7f

Zobrazit plný text záznamu

Akademický článek

Comparative analysis of genetic variants in pleural fluids and solid tissue biopsies of pleural mesothelioma patients: Implications for molecular heterogeneity assessment

Autor: Roberto Silvestri, Filomena Rea, Marianna Vitiello, Gabriele Moretti, Vittorio Aprile, Marco Lucchi, Paolo Aretini, Chiara Maria Mazzanti, Stefano Landi, Federica Gemignani

Publikováno v: Heliyon, Vol 10, Iss 11, Pp e32152- (2024)

Objectives: This study aims to determine whether the sequencing of DNA extracted from pleural fluids (PFs) of Pleural Mesothelioma (PM) patients accurately represents the genetic information obtained from the solid tissue counterpart biopsies with pa

Externí odkaz: https://doaj.org/article/4e2a57cd4d2047b8b378ebb94f5af9b0

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Exploring Regorafenib Responsiveness and Uncovering Molecular Mechanisms in Recurrent Glioblastoma Tumors through Longitudinal In Vitro Sampling

Autor: Mariangela Morelli, Francesca Lessi, Sara Franceschi, Gianmarco Ferri, Manuel Giacomarra, Michele Menicagli, Carlo Gambacciani, Francesco Pieri, Francesco Pasqualetti, Nicola Montemurro, Paolo Aretini, Orazio Santo Santonocito, Anna Luisa Di Stefano, Chiara Maria Mazzanti

Publikováno v: Cells, Vol 13, Iss 6, p 487 (2024)

Glioblastoma, a deadly brain tumor, shows limited response to standard therapies like temozolomide (TMZ). Recent findings from the REGOMA trial underscore a significant survival improvement offered by Regorafenib (REGO) in recurrent glioblastoma. Our

Externí odkaz: https://doaj.org/article/cb05bb8548ac4d87af3236dc9cdad224

Zobrazit plný text záznamu

Plný text ve formátu HTML