Zobrazeno 1 - 10
of 100
pro vyhledávání: '"P. Andy Li"'
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 467 (2024)
B355252 is a small molecular compound known for potentiating neural growth factor and protecting against neuronal cell death induced by glutamate in vitro and cerebral ischemia in vivo. However, its other biological functions remain unclear. This stu
Externí odkaz:
https://doaj.org/article/96251638ddd345e7b61efb5c8fec5e8f
Autor:
Fang Wang MM, Wenjun Wang MD, Xiaoting Wu MM, Cui Tang MM, Fang Du MD, Zhiguo Lu MM, Zhuoyang Zhang BS, Hui Xu MM, Xiangmei Cao MD, P. Andy Li MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Among all malignancies worldwide, gastric cancer is the fifth most common cancer with the third highest mortality rate. One of the main reasons for the low survival rate is the recurrence and metastasis that occurs in many patients after surgery. Num
Externí odkaz:
https://doaj.org/article/0186d323addb40c593dfae225af5883c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Tumor necrosis factor-α-induced protein 8 (TNFAIP8) is a member of the TIPE/TNFAIP8 family which regulates tumor growth and survival. Our goal is to delineate the detailed oncogenic role of TNFAIP8 in skin cancer development and progression
Externí odkaz:
https://doaj.org/article/710c00f389104119aaf99dc155064fa1
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 610 (2023)
Neuroprotective drugs to protect the brain against cerebral ischemia and reperfusion (I/R) injury are urgently needed. Mammalian cell-produced recombinant human erythropoietin (rhuEPOM) has been demonstrated to have excellent neuroprotective function
Externí odkaz:
https://doaj.org/article/bd627d199349486982072b72704b4b42
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/4c9c8cbcc0194653b0003b93b0b8c283
Autor:
Farooqahmed S. Kittur, Yuan Lin, Elena Arthur, Chiu-Yueh Hung, P. Andy Li, David C. Sane, Jiahua Xie
Publikováno v:
Biochemistry and Biophysics Reports, Vol 17, Iss , Pp 157-168 (2019)
Background: Recombinant human erythropoietin (rhuEPO) and asialoerythropoietin (asialo-rhuEPO) are cardioprotective. However, the protective effects of rhuEPO could not be translated into clinical practice because of its hematopoiesis-associated side
Externí odkaz:
https://doaj.org/article/171dd6714c884032ab0f1927a967064a
Publikováno v:
BMC Neuroscience, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Cobalt chloride (CoCl2) induces chemical hypoxia through activation of hypoxia-inducible factor-1 alpha (HIF-1α). Mammalian target of rapamycin (mTOR) is a multifaceted protein capable of regulating cell growth, angiogenesis, met
Externí odkaz:
https://doaj.org/article/4034e869ff404f8a9803118b3752dd1e
Autor:
Hua Li, Farooqahmed S. Kittur, Chiu-Yueh Hung, P. Andy Li, Xinghong Ge, David C. Sane, Jiahua Xie
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Understanding proteomic changes in the ischemic penumbra are crucial to rescue those salvageable cells and reduce the damage of an ischemic stroke. Since the penumbra region is dynamic with heterogeneous cells/tissues, tissue sampling from animal mod
Externí odkaz:
https://doaj.org/article/bec1b1a97f8c4877a7fb470f4d23f56d
Autor:
Pierre J. Magistretti, Fred H. Geisler, Jay S. Schneider, P. Andy Li, Hubert Fiumelli, Simonetta Sipione
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative functions. Clinical development of ganglioside replacement therapy for several neurodegener
Externí odkaz:
https://doaj.org/article/3dcb4a510a374c26b61701b71af8366a
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 3, Pp 270-276 (2011)
Mitochondrial dysfunction plays an important role in mediating ischemic brain damage. Immp2l is an inner mitochondrial membrane peptidase that processes mitochondrial protein cytochrome c1 (Cyc1). Homozygous mutation of Immp2l (Immp2lTg(Tyr)979Ove or
Externí odkaz:
https://doaj.org/article/73157438150a4f1c9253fdcc23574f13