Revitalizing an important field in biophysics: The new frontiers of molecular crowding

Autor: Marco Cammarata, Francesco Piazza, Germán Rivas, Giorgio Schirò, Piero Andrea Temussi, Annalisa Pastore

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

Taking into account the presence of the crowded environment of a macromolecule has been an important goal of biology over the past 20 years. Molecular crowding affects the motions, stability and the kinetic behaviour of proteins. New powerful approac

Externí odkaz: https://doaj.org/article/41037760143e4de9ae89a36f2099f3ad

The anatomy of unfolding of Yfh1 is revealed by site-specific fold stability analysis measured by 2D NMR spectroscopy

Autor: Rita Puglisi, Gogulan Karunanithy, D. Flemming Hansen, Annalisa Pastore, Piero Andrea Temussi

Publikováno v: Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)

Solution NMR provides an information-rich technique to monitor the unfolding process and probe the heterogeneity of protein unfolding. Differences in unfolding dynamics of core and peripheral residues during the cold denaturation of Yfh1 are followed

Externí odkaz: https://doaj.org/article/dbcd8570f9bf4e3c8733224a6a4c24ab

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The LAGUNA design study- towards giant liquid based underground detectors for neutrino physics and astrophysics and proton decay searches

Autor: LAGUNA Collaboration, Angus, D., Ariga, A., Autiero, D., Apostu, A., Badertscher, A., Bennet, T., Bertola, G., Bertola, P. F., Besida, O., Bettini, A., Booth, C., Borne, J. L., Brancus, I., Bujakowsky, W., Campagne, J. E., Danil, G. Cata, Chipesiu, F., Chorowski, M., Cripps, J., Curioni, A., Davidson, S., Declais, Y., Drost, U., Duliu, O., Dumarchez, J., Enqvist, T., Ereditato, A., von Feilitzsch, F., Fynbo, H., Gamble, T., Galvanin, G., Gendotti, A., Gizicki, W., Goger-Neff, M., Grasslin, U., Gurney, D., Hakala, M., Hannestad, S., Haworth, M., Horikawa, S., Jipa, A., Juget, F., Kalliokoski, T., Katsanevas, S., Keen, M., Kisiel, J., Kreslo, I., Kudryastev, V., Kuusiniemi, P., Labarga, L., Lachenmaier, T., Lanfranchi, J. C., Lazanu, I., Lewke, T., Loo, K., Lightfoot, P., Lindner, M., Longhin, A., Maalampi, J., Marafini, M., Marchionni, A., Margineanu, R. M., Markiewicz, A., Marrodan-Undagoita, T., Marteau, J. E., Matikainen, R., Meindl, Q., Messina, M., Mietelski, J. W., Mitrica, B., Mordasini, A., Mosca, L., Moser, U., Nuijten, G., Oberauer, L., Oprina, A., Paling, S., Pascoli, S., Patzak, T., Pectu, M., Pilecki, Z., Piquemal, F., Potzel, W., Pytel, W., Raczynski, M., Rafflet, G., Ristaino, G., Robinson, M., Rogers, R., Roinisto, J., Romana, M., Rondio, E., Rossi, B., Rubbia, A., Sadecki, Z., Saenz, C., Saftoiu, A., Salmelainen, J., Sima, O., Slizowski, J., Slizowski, K., Sobczyk, J., Spooner, N., Stoica, S., Suhonen, J., Sulej, R., Szarska, M., Szeglowski, T., Temussi, M., Thompson, J., Thompson, L., Trzaska, W. H., Tippmann, M., Tonazzo, A., Urbanczyk, K., Vasseur, G., Williams, A., Winter, J., Wojutszewska, K., Wurm, M., Zalewska, A., Zampaolo, M., Zito, M.

The feasibility of a next generation neutrino observatory in Europe is being considered within the LAGUNA design study. To accommodate giant neutrino detectors and shield them from cosmic rays, a new very large underground infrastructure is required.

Externí odkaz: http://arxiv.org/abs/1001.0077

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