Zobrazeno 1 - 10
of 971
pro vyhledávání: '"P. A. Northcott"'
Autor:
Quynh T. Tran, Alex Breuer, Tong Lin, Ruth Tatevossian, Sariah J. Allen, Michael Clay, Larissa V. Furtado, Mark Chen, Dale Hedges, Tylman Michael, Giles Robinson, Paul Northcott, Amar Gajjar, Elizabeth Azzato, Sheila Shurtleff, David W. Ellison, Stanley Pounds, Brent A. Orr
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract As part of the advancement in therapeutic decision-making for brain tumor patients at St. Jude Children’s Research Hospital (SJCRH), we developed three robust classifiers, a deep learning neural network (NN), k-nearest neighbor (kNN), and
Externí odkaz:
https://doaj.org/article/04b24c66871347abb0fb60d227703a96
Publikováno v:
Discover Psychology, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background and aim Following a stroke, around a quarter of people will have aphasia, a language disability. Aphasia can have a devastating long-term impact on a person’s psychological wellbeing, yet their language difficulties make it chal
Externí odkaz:
https://doaj.org/article/b81d4ba8c1c046e490cb2f4419da832a
Autor:
Christin Schmidt, Sarah Cohen, Brian L. Gudenas, Sarah Husain, Annika Carlson, Samantha Westelman, Linyu Wang, Joanna J. Phillips, Paul A. Northcott, William A. Weiss, Bjoern Schwer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract SNCAIP duplication may promote Group 4 medulloblastoma via induction of PRDM6, a poorly characterized member of the PRDF1 and RIZ1 homology domain-containing (PRDM) family of transcription factors. Here, we investigated the function of PRDM6
Externí odkaz:
https://doaj.org/article/f24a13935b9e45c388a2ca2c8a1ffbb3
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Estrogens are a growing problem in wastewater discharges because they are continuously entering the environment and are biologically active at extremely low concentrations. Their effects on wildlife were first identified several decades before, but t
Externí odkaz:
https://doaj.org/article/c01c4456de634f02aee11a2e52cc0bb6
Loss of Elp1 in cerebellar granule cell progenitors models ataxia phenotype of Familial Dysautonomia
Autor:
Frederik Arnskötter, Patricia Benites Goncalves da Silva, Mackenna E. Schouw, Chiara Lukasch, Luca Bianchini, Laura Sieber, Jesus Garcia-Lopez, Shiekh Tanveer Ahmad, Yiran Li, Hong Lin, Piyush Joshi, Lisa Spänig, Magdalena Radoš, Mykola Roiuk, Mari Sepp, Marc Zuckermann, Paul A. Northcott, Annarita Patrizi, Lena M. Kutscher
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106600- (2024)
Familial Dysautonomia (FD) is an autosomal recessive disorder caused by a splice site mutation in the gene ELP1, which disproportionally affects neurons. While classically characterized by deficits in sensory and autonomic neurons, neuronal defects i
Externí odkaz:
https://doaj.org/article/27595f3c5f8c4217868b4b0677549c70
Autor:
Lada Leyens, Carrie A. Northcott, Lesley Maloney, Marie McCarthy, Nona Dokuzova, Thomas Pfister
Publikováno v:
Digital Biomarkers, Vol 8, Iss 1, Pp 1-12 (2024)
Background: Developments in the field of digital measures and digitally derived endpoints demand greater attention on globally aligned approaches to enhance digital measure acceptance by regulatory authorities and health technology assessment (HTA) b
Externí odkaz:
https://doaj.org/article/d92f357312f34ba0a4cab59b8cee2cb1
Autor:
Louis A. Tremblay, James M. Ataria, Ian Challenger, Jacqui Horswell, Virginia Baker, E. R. Lisa Langer, Alan Leckie, Olivier Champeau, Alma Siggins, Grant L. Northcott
Publikováno v:
Pollutants, Vol 3, Iss 4, Pp 494-506 (2023)
Anthropogenic chemicals are fundamental for maintaining our standard of living in modern society. Unfortunately, some chemicals are persistent and can enter waste streams and, ultimately, the environment. Commonly used household products, including p
Externí odkaz:
https://doaj.org/article/df37e421c36a4bf1b8e10eb5da5c7be3
Autor:
Cheryl Forchuk, Sarah Benbow, Jeffrey Reiss, Sherri Lawson, Sandra Northcott, Rebecca Vann, Dan Catunto, Melissa Jeffrey, Richard Booth, Anne Peters
Publikováno v:
International Journal on Homelessness, Vol 3, Iss 3, Pp 198-213 (2023)
The “No Fixed Address” version 2 (NFAv.2) project tested the efficacy of a potential best practice program that aimed to prevent discharge from hospital into homelessness. Forchuk and colleagues developed a system that streamlined housing and soc
Externí odkaz:
https://doaj.org/article/5262c89b31ea498d8a60ae538283861d
Autor:
Max J. van Essen, Elizabeth J. Apsley, Joey Riepsaame, Ruijie Xu, Paul A. Northcott, Sally A. Cowley, John Jacob, Esther B. E. Becker
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/6dd8bd19ab6c4c6d90c14eaf46139909
Autor:
Kolokolova, Antonina, Billard, Mitchell, Bishop, Robert, Elsisy, Moustafa, Northcott, Zachary, Graves, Laura, Nagisetty, Vineel, Patey, Heather
In this paper we present a method for algorithmic melody generation using a generative adversarial network without recurrent components. Music generation has been successfully done using recurrent neural networks, where the model learns sequence info
Externí odkaz:
http://arxiv.org/abs/2010.15772
