Zobrazeno 1 - 10
of 393
pro vyhledávání: '"P. A. Konstantinopoulos"'
Autor:
I.-M. Launonen, N. Lyytikäinen, J. Casado, E. A. Anttila, A. Szabó, U.-M. Haltia, C. A. Jacobson, J. R. Lin, Z. Maliga, B. E. Howitt, K. C. Strickland, S. Santagata, K. Elias, A. D. D’Andrea, P. A. Konstantinopoulos, P. K. Sorger, A. Färkkilä
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The tumour microenvironment has not been fully characterised in high-grade serous ovarian cancers (HGSOC). Here, the authors use highly multiplexed imaging to analyse the HGSOC immune microenvironment at spatial and single-cell resolution, with clini
Externí odkaz:
https://doaj.org/article/3966d5c8320e4681ae12f840eb20d887
Autor:
Dudouet, J., Colombi, G., Tello, D. Reygadas, Michelagnoli, C., Dao, D. D., Nowacki, F., Abushawish, M., Clément, E., Costache, C., Duchêne, G., Kandzia, F., Lemasson, A., Marginean, N., Marginean, R., Mihai, C., Pascu, S., Rejmund, M., Rezynkina, K., Stezowski, O., Turturica, A., Ujeniuc, S., Astier, A., de Angelis, G., de France, G., Delafosse, C., Deloncle, I., Gadea, A., Gottardo, A., Jones, P., Konstantinopoulos, T., Kuti, I., Blanc, F. Le, Lenzi, S. M., Lozeva, R., Million, B., Pérez-Vidal, R. M., Petrache, C. M., Ralet, D., Redon, N., Schmitt, C., Sohler, D., Verney, D.
The first systematic experimental study of the neutron-rich Br isotopes with two complementary state-of-the-art techniques is presented. These isotopes have been populated in the fission process at two different facilities, GANIL and ILL. New spectro
Externí odkaz:
http://arxiv.org/abs/2405.15601
Autor:
Yajie Sun, Jeffrey Patterson-Fortin, Sen Han, Zhe Li, Zuzanna Nowicka, Yuna Hirohashi, Susan Kilgas, Jae Kyo Yi, Alexander Spektor, Wojciech Fendler, Panagiotis A. Konstantinopoulos, Dipanjan Chowdhury
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract 53BP1 nucleates the anti-end resection machinery at DNA double-strand breaks, thereby countering BRCA1 activity. Loss of 53BP1 leads to DNA end processing and homologous recombination in BRCA1-deficient cells. Consequently, BRCA1-mutant tumo
Externí odkaz:
https://doaj.org/article/d04a618cd1684767a7029059b0c86b6d
Autor:
Rezynkina, K., Dao, D. D., Duchene, G., Dudouet, J., Nowacki, F., Clement, E., Lemasson, A., Andreoiu, C., Astier, A., de Angelis, G., de France, G., Delafosse, C., Deloncle, I., Didierjean, F., Dombradi, Z., Ducoin, C., Gadea, A., Gottardo, A., Guinet, D., Jacquot, B., Jones, P., Konstantinopoulos, T., Kuti, I., Korichi, A., Lenzi, S. M., Li, G., Blanc, F. Le, Lizarazo, C., Lozeva, R., Maquart, G., Million, B., Michelagnoli, C., Napoli, D. R., Navin, A., Perez-Vidal, R. M., Petrache, C. M., Pietralla, N., Ralet, D., Ramdhane, M., Rejmund, M., Stezowski, O., Schmitt, C., Sohler, D., Verney, D.
The structure of $^{83}$As, $^{85}$As and $^{87}$As have been studied in fusion-fission reaction $^{238}$U+$^9$Be. Fission fragments were identified in mass and atomic number using the VAMOS++ spectrometer and the coincident $\gamma$-rays were detect
Externí odkaz:
http://arxiv.org/abs/2203.10108
Autor:
Panagiotis A. Konstantinopoulos, Niya Xiong, Carolyn Krasner, Joyce F. Liu, Hannah Sawyer, Madeline Polak, Hope Needham, Megan Geddes, Lani Koppermann, Meghan Shea, Cesar Castro, Su-Chun Cheng, Ursula A. Matulonis, Elizabeth K. Lee
Publikováno v:
Gynecologic Oncology Reports, Vol 52, Iss , Pp 101348- (2024)
Several lines of preclinical evidence indicate that combining PI3K and CDK4/6 inhibitors may further enhance the efficacy of hormonal therapy by overcoming de novo and acquired resistance to PI3K and CDK4/6 blockade. We evaluated the combination of a
Externí odkaz:
https://doaj.org/article/a58a03d3330d4b9d9bd8d84d99a74acc
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundPatients with platinum-resistant recurrent high grade serous ovarian carcinoma have poor outcomes and limited treatment options.Case presentationWe present a case of a 48-year-old woman with platinum-resistant high grade serous ovarian carc
Externí odkaz:
https://doaj.org/article/f11e3fa3b6a247dcb107112f535477c8
Publikováno v:
Knowledge, Vol 3, Iss 4, Pp 525-542 (2023)
Cooperation is an important aspect of open innovation (OI) facilitated by information and communication technology (ICT). Cooperation may have two distinct forms, namely dialectic or dialogic, and it has already been argued that dialogic cooperation
Externí odkaz:
https://doaj.org/article/31c2d6d0405b437bb49b895279ee00c1
Autor:
Kevin Elias, Urszula Smyczynska, Konrad Stawiski, Zuzanna Nowicka, James Webber, Jakub Kaplan, Charles Landen, Jan Lubinski, Asima Mukhopadhyay, Dona Chakraborty, Denise C. Connolly, Heather Symecko, Susan M. Domchek, Judy E. Garber, Panagiotis Konstantinopoulos, Wojciech Fendler, Dipanjan Chowdhury
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Identifying germline BRCA1/2 mutation carriers is vital for reducing their risk of breast and ovarian cancer. To derive a serum miRNA-based diagnostic test we used samples from 653 healthy women from six international cohorts, including 350
Externí odkaz:
https://doaj.org/article/a02df781daaa4b0c894cbc2fcadb377a
Autor:
Sara M Tolaney, James Lindsay, Michael Manos, Biagio Ricciuti, Anita Giobbie-Hurder, Scott J Rodig, Joao V Alessi, Mark M Awad, Sandro Santagata, Bruce E Johnson, Glenn J Hanna, Elio Adib, Jason Weirather, Xinan Wang, Bijaya Sharma, Kathleen Pfaff, Kristen D Felt, William Lotter, Panagiotis Konstantinopoulos, Madison Turner, Federica Pecci, Emma L Welsh, Stephanie M Jones, Jennifer O Altreuter, Ian D Dryg, Alessandro Di Federico, Malini M Gandhi, Sabrina J Chan, Marta Holovatska, Melissa E Hughes, O’Meara Tess A, Neal I Lindeman, Jennifer Curtis, Peter K Sorger, Ethan Cerami, Lynette M Sholl, Jonathan A Novak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/02ccda4c59ce49c1ba7f9100a145659a
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