Zobrazeno 1 - 10
of 2 796
pro vyhledávání: '"P. A. Furth"'
Autor:
Simon Isaiah, Johan A. Westerhuis, Du Toit Loots, Regan Solomons, Marceline Tutu van Furth, Sabine van Elsland, Martijn van der Kuip, Shayne Mason
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tuberculous meningitis (TBM)—the extrapulmonary form of tuberculosis, is the most severe complication associated with tuberculosis, particularly in infants and children. The gold standard for the diagnosis of TBM requires cerebrospinal flu
Externí odkaz:
https://doaj.org/article/a0c54fb8cb6043c483012741dd11ab40
Autor:
Stephanie Bela Andela, Holger Amthauer, Christian Furth, Julian M. Rogasch, Marcus Beck, Felix Mehrhof, Pirus Ghadjar, Jörg van den Hoff, Tobias Klatte, Rana Tahbaz, Daniel Zips, Frank Hofheinz, Sebastian Zschaeck
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background PSMA-PET is increasingly used for staging prostate cancer (PCA) patients. However, it is not clear if quantitative imaging parameters of positron emission tomography (PET) have an impact on disease progression and are thus importa
Externí odkaz:
https://doaj.org/article/2cd9702345744663b11a692d8b95dabe
Protocol for unified metabolomics and proteomics analysis of formalin-fixed paraffin-embedded tissue
Autor:
Abisola R. Isaiah, Laneke Luies, Du Toit Loots, Aurelia A. Williams, Maré Vlok, Novel N. Chegou, Marceline Tutu van Furth, Martijn van der Kuip, Shayne Mason
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103442- (2024)
Summary: The use of archival formalin-fixed paraffin-embedded (FFPE) tissue samples for biochemical analyses is problematic because of the formation of a Schiff base, leading to low protein and metabolite yields during analytical extractions. Here, w
Externí odkaz:
https://doaj.org/article/b5efd3dadc0a4c91a1f0aa465e0dfaa6
Autor:
Hyeon Hwa Kim, Hye Kyung Lee, Lothar Hennighausen, Priscilla A. Furth, Heungsup Sung, Jin Won Huh
Publikováno v:
Vaccine: X, Vol 20, Iss , Pp 100565- (2024)
The widespread administration of an additional dose of the SARS-CoV-2 vaccine has been promoted across adult populations, demonstrating a robust immune response against COVID-19. Longitudinal studies provide crucial data on the durability of immune r
Externí odkaz:
https://doaj.org/article/176f010e6b804221b7174459c8b0aafd
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
There is compelling evidence that a dysregulated immune inflammatory response in neuroinfectious diseases results in modifications in metabolic processes and altered metabolites, directly or indirectly influencing lipid metabolism within the central
Externí odkaz:
https://doaj.org/article/b2ec0dc498114e99aaee3b2ad2e96900
Autor:
Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander Plotnikov, Haim Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth, Efrat Shema
Publikováno v:
eLife, Vol 13 (2024)
Diffuse midline gliomas (DMGs) are aggressive and fatal pediatric tumors of the central nervous system that are highly resistant to treatments. Lysine to methionine substitution of residue 27 on histone H3 (H3-K27M) is a driver mutation in DMGs, resh
Externí odkaz:
https://doaj.org/article/d63328b5980f4190895f7d76cb98e2cf
Autor:
Simon Isaiah, Du Toit Loots, A. Marceline Tutu van Furth, Elmarie Davoren, Sabine van Elsland, Regan Solomons, Martijn van der Kuip, Shayne Mason
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background The pathogenesis of tuberculous meningitis (TBM) involves infection by Mycobacterium tuberculosis in the meninges and brain. However, recent studies have shown that the immune response and inflammatory processes triggered by TBM c
Externí odkaz:
https://doaj.org/article/bc5b9b1cf72d40c79a6c7449872fb43c
Autor:
Markus Hoffmann, Lina-Liv Willruth, Alexander Dietrich, Hye Kyung Lee, Ludwig Knabl, Nico Trummer, Jan Baumbach, Priscilla A. Furth, Lothar Hennighausen, Markus List
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in biomedical research but is still rarely used in clinical practice. In this study, we propose that RNA-seq should be considered a diagnostic tool, as it
Externí odkaz:
https://doaj.org/article/8467cfc803f64d2c807e7f55678a08f9
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-5 (2024)
Abstract Objective The diagnosis of neurosarcoidosis (NS) remains challenging due to the difficulty to obtain central nervous system (CNS) biopsies. Various diagnostic parameters are considered for the definition of possible, probable and definite NS
Externí odkaz:
https://doaj.org/article/4c303cde110e44fb923233b684a67fcd
Autor:
Kaishu Mason, Anuja Sathe, Paul R. Hess, Jiazhen Rong, Chi-Yun Wu, Emma Furth, Katalin Susztak, Jonathan Levinsohn, Hanlee P. Ji, Nancy Zhang
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-33 (2024)
Abstract Existing methods for analysis of spatial transcriptomic data focus on delineating the global gene expression variations of cell types across the tissue, rather than local gene expression changes driven by cell-cell interactions. We propose a
Externí odkaz:
https://doaj.org/article/584d5b43dfac4a9b8622ba36a4824e07