Zobrazeno 1 - 10
of 59
pro vyhledávání: '"P. M. Brophy"'
A dominance of Mu class glutathione transferases within the equine tapeworm Anoplocephala perfoliata
Autor:
Holly M. Northcote, Boontarikaan Wititkornkul, David J. Cutress, Nathan D. Allen, Peter M. Brophy, Ruth E. Wonfor, Russell M. Morphew
Publikováno v:
Parasitology, Vol 151, Pp 282-294 (2024)
The most common equine tapeworm, Anoplocephala perfoliata, has often been neglected amongst molecular investigations and has been faced with limited treatment options. However, the recent release of a transcriptome dataset has now provided opportunit
Externí odkaz:
https://doaj.org/article/2329217313744948bb9ad246c58ff837
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on cardiovascular and renal outcomes has not been systematically reviewed across baseline kidney function groups. We conducted a systematic review and meta-analysis of randomi
Externí odkaz:
https://doaj.org/article/399210e51d194ef9aefcb20d0271ab51
Autor:
Linda Papa, Gretchen M. Brophy, Wilmer Alvarez, Robert Hirschl, Marshall Cress, Kurt Weber, Philip Giordano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-terminal hydrolase (UCH-L1) have been FDA-approved for clinical use in mild and moderate traumatic brain injury (TBI). Understanding sex differences in their diagnostic accuracy over tim
Externí odkaz:
https://doaj.org/article/60db9656835e40c78fe504024ead5243
Autor:
Rhys Aled Jones, Chelsea N. Davis, Justyna Nalepa‐Grajcar, Hayley Woodruff, Hefin Wyn Williams, Peter M. Brophy, Emma Jones
Publikováno v:
Environmental DNA, Vol 6, Iss 1, Pp n/a-n/a (2024)
Abstract Environmental DNA (eDNA) is a powerful tool for identifying the spatial and temporal presence and density of species in a range of aquatic habitats. The analysis of eDNA has a wide range of application, one of which may be to inform of Fasci
Externí odkaz:
https://doaj.org/article/1cfce0402615443a84c811a6589795d6
Autor:
James M. Brophy, MD, PhD
Publikováno v:
CJC Open, Vol 5, Iss 5, Pp 401- (2023)
Externí odkaz:
https://doaj.org/article/c04f77675e88415cbdd4d5a3a21a63de
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 24 (2022)
Background Recent studies have reported that dihydropyridine calcium channel blockers (dCCBs) may increase the risk of pancreatic cancer, but these studies had methodological limitations. We thus aimed to determine whether dCCBs are associated with a
Externí odkaz:
https://doaj.org/article/cd3f7a04db884b14b61318b24cd6578a
Autor:
Stéphane Rinfret, MD, SM, Israth Jahan, BSc, Kevin McKenzie, Nandini Dendukuri, PhD, Kevin R. Bainey, MD, MSc, Samer Mansour, MD, Madhu Natarajan, MD, Luiz F. Ybarra, MD, PhD, MBA, Aun-Yeong Chong, BSc, MBBS, MD, MRCP, Simon Bérubé, MD, Robert Breton, MD, Michael J. Curtis, MD, Josep Rodés-Cabau, MD, Amlani Shy (Shoaib), MD, Alireza Bagherli, MD, Warren Ball, MD, Alan Barolet, MD, PhD, Hussein K. Beydoun, MD, Neil Brass, MD, Albert W. Chan, MD, MSc, Franco Colizza, MD, Christian Constance, MD, Neil P. Fam, MD, MSc, François Gobeil, MD, Tinouch Haghighat, MD, Steven Hodge, MD, Dominique Joyal, MD, Hahn Hoe Kim, MD, CM, Sohrab Lutchmedial, MD, Andrea MacDougall, MD, Paul Malik, MD, Steve Miner, MD, Kunal Minhas, BSc, MD, Jason Orvold, MD, Donald Palisaitis, MD, Brendan Parfrey, MD, Jean-Michel Potvin, MD, Geoffrey Puley, MD, Sam Radhakrishnan, MD, Marco Spaziano, MD, Jean-François Tanguay, MD, Ram Vijayaraghaban, MD, John G. Webb, MD, Rodney H. Zimmermann, MD, David A. Wood, James M. Brophy, MD, PhD
Publikováno v:
CJC Open, Vol 3, Iss 9, Pp 1125-1131 (2021)
Background: As a result of the COVID-19 pandemic first wave, reductions in ST-elevation myocardial infarction (STEMI) invasive care, ranging from 23% to 76%, have been reported from various countries. Whether this change had any impact on coronary an
Externí odkaz:
https://doaj.org/article/a8bf8c71b9a14374baffa5709e52ace1
Autor:
Todd C. Lee, Emily G. McDonald, Guillaume Butler-Laporte, Luke B. Harrison, Matthew P. Cheng, James M. Brophy
Publikováno v:
International Journal of Infectious Diseases, Vol 104, Iss , Pp 671-676 (2021)
Background: The global death toll from coronavirus disease 2019 (COVID-19) has exceeded 2 million, and treatments to decrease mortality are needed urgently. Objectives: To examine the probabilities of a clinically meaningful reduction in mortality fo
Externí odkaz:
https://doaj.org/article/8b0e6d16663944b2a5a4838efaf6dc20
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/e44b02d5eede4c53b63a1c65b3eaa827
Autor:
Jamie E. Meegan, Padmini Komalavilas, Joyce Cheung‐Flynn, Tsz Wing Yim, Nathan D. Putz, Jordan J. Jesse, Kyle D. Smith, Tatiana N. Sidorova, Han Noo Ri Lee, Toria Tomasek, Ciara M. Shaver, Lorraine B. Ware, Colleen M. Brophy, Julie A. Bastarache
Publikováno v:
Physiological Reports, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Sepsis is a devastating disease with high morbidity and mortality and no specific treatments. The pathophysiology of sepsis involves a hyperinflammatory response and release of damage‐associated molecular patterns (DAMPs), including adenos
Externí odkaz:
https://doaj.org/article/c442a96d140a4867a2a4fce0591bff3d