Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1

Autor: Ilaria De Simone, Constance C. F. M. J. Baaten, Martine Jandrot-Perrus, Jonathan M. Gibbins, Hugo ten Cate, Johan W. M. Heemskerk, Chris I. Jones, Paola E. J. van der Meijden

Publikováno v: International journal of molecular sciences 23(18), 10203 (2022). doi:10.3390/ijms231810203 special issue: "Special Issue "Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation 2.0" / Special Issue Editors: Dr. Kerstin Jurk, Guest Editor; Dr. Marijke J.E. Kuijpers, Guest Editor; Prof. Dr. Johan W. M. Heemskerk, Guest Editor"
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10203
International journal of molecular sciences, 23(18):10203. Multidisciplinary Digital Publishing Institute (MDPI)

International journal of molecular sciences 23(18), 10203 (2022). doi:10.3390/ijms231810203 special issue: "Special Issue "Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation 2.0" / Special Issue Editors: Dr. Kerstin Jurk, Guest E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6f435355a06d55d0ea586c2d31dad1

Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity

Autor: Pepin, Marion, Mezouar, Soraya, Pegon, Julie, Muczynski, Vincent, Adam, Frédéric, Bianchini, Elsa P, Bazaa, Amine, Proulle, Valerie, Rupin, Alain, Paysant, Jerome, Panicot-Dubois, Laurence, Christophe, Olivier D., Dubois, Christophe, Lenting, Peter J, Denis, Cécile V

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.37953. ⟨10.1038/srep37953⟩
Scientific Reports, 2016, 6 (1), pp.37953. ⟨10.1038/srep37953⟩

International audience; Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b0ddd5764163b44fce0bc2bdd8f26d60
https://pubmed.ncbi.nlm.nih.gov/27892504

Platelets modulate the immune response following trauma by interaction with CD4+ T regulatory cells in a mouse model

Autor: Friederike Hefele, Stefan Huber-Wagner, Christian B. Bergmann, Marina Unger, Marc Hanschen, Martijn van Griensven, Peter Biberthaler

Publikováno v: Immunologic Research, 64(2), 508-517. Humana Press, Inc.

CD4+ T regulatory cells (Tregs) play a pivotal role in the anti-inflammatory immune response following trauma. The mechanisms of CD4+ Treg activation are mostly unknown. Here, we hypothesize that platelets regulate CD4+ Treg activation following trau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95fc0edc2f5445800c88f14c5a48cf4
https://pubmed.ncbi.nlm.nih.gov/26471021

Physical activity limits pulmonary endothelial activation in sickle cell SAD mice

Autor: Camille Faes, Aymen Romdhani, Vanessa Bourgeaux, Emmanuelle Charrin, Cyril Martin, Aymeric Douillard, Amine Bessaad, Geneviève De Souza, Emeline Aufradet, Erica N. Chirico, Vincent Pialoux, Emmanuelle Canet-Soulas

Publikováno v: Blood
Blood, American Society of Hematology, 2014, 123 (17), pp.2745-7. ⟨10.1182/blood-2013-10-534982⟩

To the editor: Vaso-occlusion (VOC) in sickle cell disease (SCD) results from many pathophysiological mechanisms including sickling of red blood cells, hemolysis, inflammation, vascular adhesion, and reduced nitric oxide (NO) bioavailability.[1][1] A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc984cad1606d7b75b6154d144fd861e
https://pubmed.ncbi.nlm.nih.gov/24764563