Zobrazeno 1 - 10
of 188
pro vyhledávání: '"P-S Low"'
Autor:
Patrick Bou-Samra, MD, Austin Chang, BA, Emily Guo, BA, Feredun Azari, MD, Gregory Kennedy, MD, Azra Din, MPH, Taine Pechet, MD, Doraid Jarrar, MD, John Kucharczuk, MD, Jarrod Predina, MD, James Delikatny, PhD, Philip S. Low, PhD, Sunil Singhal, MD
Publikováno v:
Annals of Thoracic Surgery Short Reports, Vol 2, Iss 3, Pp 432-437 (2024)
Background: Intraoperative molecular imaging (IMI) uses a cancer-targeted fluorescent agent injected into patients to localize tumor nodules. Pafolacianine is a folate receptor (FR)–targeted near-infrared fluorescent probe. Almost 10% of patients h
Externí odkaz:
https://doaj.org/article/4dd803d4e4eb4522b467f59e997dc021
Autor:
Nick Sevdalis, Andrew Walker, Natasha Curran, Louise M Goff, Joseph T S Low, Sally Irwin, Sophie Lowry, Oliver Brady
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Objectives To assess the feasibility and acceptability of delivering Healthy Eating and Active Lifestyles for Diabetes (HEAL-D) Online.Intervention HEAL-D Online—a 7-week culturally tailored type 2 diabetes educational programme delivered using onl
Externí odkaz:
https://doaj.org/article/118b18178c5340ba8846d7ad1c4f2bdb
Autor:
Ahmed M. Abdelaal, Ikjot S. Sohal, Shreyas G. Iyer, Kasireddy Sudarshan, Esteban A. Orellana, Kenan E. Ozcan, Andrea P. dos Santos, Philip S. Low, Andrea L. Kasinski
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102193- (2024)
Use of tumor-suppressive microRNAs (miRNAs) as anti-cancer agents is hindered by the lack of effective delivery vehicles, entrapment of the miRNA within endocytic compartments, and rapid degradation of miRNA by nucleases. To address these issues, we
Externí odkaz:
https://doaj.org/article/c4e68e8c068a410f86d873750e696cff
Autor:
Yun Chang, Gyuhyung Jin, Weichuan Luo, Qian Luo, Juhyung Jung, Sydney N. Hummel, Sandra Torregrosa-Allen, Bennett D. Elzey, Philip S. Low, Xiaojun Lance Lian, Xiaoping Bao
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 168-180 (2023)
Adoptive chimeric antigen receptor (CAR)-engineered natural killer (NK) cells have shown promise in treating various cancers. However, limited immunological memory and access to sufficient numbers of allogenic donor cells have hindered their broader
Externí odkaz:
https://doaj.org/article/132da242ecf24ecdaf6268b9a29f76ac
Autor:
Fenghua Zhang, Bo Huang, Sagar M. Utturkar, Weichuan Luo, Gregory Cresswell, Seth A. Herr, Suilan Zheng, John V. Napoleon, Rina Jiang, Boning Zhang, Muyi Liu, Nadia Lanman, Madduri Srinivasarao, Timothy L. Ratliff, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Folate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and myeloid-deri
Externí odkaz:
https://doaj.org/article/6dc8dbece4744d66b4109cdad3fb1700
Autor:
Rami Alfar, John V. Napoleon, Imrul Shahriar, Richard Finnell, Cole Walchle, Austin Johnson, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Folate receptor delta (FRδ) has been used as a biomarker for regulatory T cells (Tregs), because its expression is limited to Tregs and ovum. Although FRδ is unable to bind folate, we have used molecular docking software to identify a folate congen
Externí odkaz:
https://doaj.org/article/91df2ad8c7494fd8a1ab5e850d97e190
Autor:
Jeffery J. Nielsen, Stewart A. Low, Christopher Chen, Xinlan Li, Ephraim Mbachu, Lina Trigg, Siyuan Sun, Madeline Tremby, Rahul Hadap, Philip S. Low
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 612 (2024)
Spinal fusions are performed to treat congenital skeletal malformations, spondylosis, degenerative disk diseases, and other pathologies of the vertebrae that can be resolved by reducing motion between neighboring vertebrae. Unfortunately, up to 100,0
Externí odkaz:
https://doaj.org/article/a3b7071675f74c859133e0f99b3529a4
Autor:
Maxwell W. G. Miner, Heidi Liljenbäck, Jenni Virta, Salli Kärnä, Riikka Viitanen, Petri Elo, Maria Gardberg, Jarmo Teuho, Piritta Saipa, Johan Rajander, Hasan Mansour A Mansour, Nathan A. Cleveland, Philip S. Low, Xiang-Guo Li, Anne Roivainen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNon-invasive imaging techniques such as positron emission tomography (PET) are extremely important for cancer detection and characterization especially for difficult to biopsy or extremely delicate organs such as the brain. The folate ana
Externí odkaz:
https://doaj.org/article/9d40fb1ffac1438f88d17102de90bf4e
Autor:
Yingwen Hu, Danyang Chen, John V. Napoleon, Madduri Srinivasarao, Sunil Singhal, Cagri A. Savran, Philip S. Low
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Retrieval of circulating tumor cells (CTC) has proven valuable for assessing a patient's cancer burden, evaluating response to therapy, and analyzing which drug might treat a cancer best. Although most isolation methods retrieve CTCs based o
Externí odkaz:
https://doaj.org/article/94820e1958bd4c72822ccd227b145a1c
Autor:
Gregory T. Kennedy, Feredun S. Azari, Elizabeth Bernstein, Bilal Nadeem, Ashley Chang, Alix Segil, Sean Carlin, Neil T. Sullivan, Emmanuel Encarnado, Charuhas Desphande, Sumith Kularatne, Pravin Gagare, Mini Thomas, John C. Kucharczuk, Gaetan Christien, Francois Lacombe, Kaela Leonard, Philip S. Low, Aline Criton, Sunil Singhal
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Radiography identifies suspicious lung nodules that are not always easy to diagnose via biopsy. Here, the authors utilize a fluorescent dye that targets the folate receptor and show using needle based endomicroscopy that it can be used to identify ca
Externí odkaz:
https://doaj.org/article/2265f9b6134146e6a3286c12a2c662bd