Zobrazeno 1 - 4
of 4
pro vyhledávání: '"P-Glycoprotein/genetics"'
Autor:
Alain Malafosse, Gilles Bertschy, Nader Perroud, Rudolf Uher, Guido Bondolfi, Jean-Michel Aubry, Markus Kosel, Marianne Gex-Fabry
Publikováno v:
Pharmacogenomics, Vol. 12, No 3 (2011) pp. 365-77
Aims: This study investigated clinical and genetic predictors of increasing suicidal ideation during antidepressant treatment. Materials & methods: A total of 131 depressed outpatients were allocated to four antidepressants (paroxetine, venlafaxine,
Autor:
Beatrice Oneda, Nicola Gérard Gervasoni, Marianne Gex-Fabry, Gilles Bertschy, Guido Bondolfi, Jean-Michel Aubry, Chin B. Eap
Publikováno v:
Therapeutic Drug Monitoring, Vol. 30, No 4 (2008) pp. 474-82
Paroxetine is characterized by large interindividual pharmacokinetic variability and heterogeneous response patterns. The present study investigates plasma concentration and therapeutic response to paroxetine for the influence of age, sex, and CYP2D6
Autor:
Jean-François Ghersi-Egea, J. Donald Ostrow, Nathalie Strazielle, Claudio Tiribelli, Charlotte Schmitt, Silvia Gazzin, Michelle Fèvre-Montange
Publikováno v:
The Journal of comparative neurology. 510(5)
Cerebral homeostasis results from the presence of the protective blood-brain and blood-cerebrospinal fluid barriers located respectively at the brain capillary endothelium and the choroid plexus epithelium. ABCb1 (Pgp) and ABCc1 (Mrp1) transporters a
Autor:
Arnaud G, L'Huillier, Kuntheavy, Ing Lorenzini, Pierre-Alex, Crisinel, Michela C, Rebsamen, Joel, Fluss, Christian M, Korff, Remy P, Barbe, Claire-Anne, Siegrist, Pierre, Dayer, Klara M, Posfay-Barbe, Jules A, Desmeules, Barbara, Wildhaber
Publikováno v:
Pharmacogenomics, Vol. 12, No 10 (2011) pp. 1493-501
Aims: To examine the safety profile of oseltamivir in children and evaluate the impact of P-glycoprotein polymorphisms on the incidence of neuropsychiatric adverse events (NPAE) in oseltamivir-treated children. Subjects & methods: This prospective co