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Akademický článek

Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response.

Autor: Thomas H P M Habets, Tammy Oth, Ans W Houben, Mirelle J A J Huijskens, Birgit L M G Senden-Gijsbers, Melanie C A Schnijderberg, Boudewijn Brans, Ludwig J Dubois, Philippe Lambin, Marijke De Saint-Hubert, Wilfred T V Germeraad, Marcel G J Tilanus, Felix M Mottaghy, Gerard M J Bos, Joris Vanderlocht

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159515 (2016)

Accumulating evidence indicates that fractionated radiotherapy (RT) can result in distant non-irradiated (abscopal) tumour regression. Although preclinical studies indicate the importance of T cells in this infrequent phenomenon, these studies do not

Externí odkaz: https://doaj.org/article/19bc78f882ea4f7caa6a85b3c6b4f0fd

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A 1-year comparison of the efficacy and clinical tolerance in postmenopausal women of two hormone replacement therapies containing estradiol in combination with either norgestrel or trimegestone

Autor: J H, Meuwissen, L, Beijers-De Bie, T, Vihtamaki, R, Tuimala, N, Siseles, C, Magaril, H S, The, P W, Houben, M, Murga, D, Spielmann, T J, De Villiers

Publikováno v: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 15(5)

This double-blind, randomized, multi-center study compared the efficacy and clinical tolerance of a combined formulation containing 2 mg estradiol (E2) and 0.5 mg trimegestone (TMG) with a standard hormone replacement therapy containing estradiol val

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2794102bad915806bbc8b4ce799dfb41
https://pubmed.ncbi.nlm.nih.gov/11727357

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Ki-67 immunoquantitation in cervical intraepithelial neoplasia (CIN): a sensitive marker for grading

Autor: A J, Kruse, J P, Baak, P C, de Bruin, M, Jiwa, W P, Snijders, P J, Boodt, G, Fons, P W, Houben, H S, The

Publikováno v: The Journal of pathology. 193(1)

The aim of this study was to assess the value of Ki-67 immunoquantitation with a computerized image analysis system for grading support in cervical intraepithelial neoplasia (CIN). Sixty-five 'blind' consensus biopsies (23 CIN 1, 22 CIN 2, and 20 CIN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c508a5f805f7ed2b4bc2d27d20a5854
https://pubmed.ncbi.nlm.nih.gov/11169515

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The Differential Regulation of the Intranuclear Progestin in Mouse Kidney and Prostate-Seminal Vesicles

Autor: P W Houben, L P Bullock

Publikováno v: Endocrine Research. 13:1-14

This study was designed to confirm the identity of the enzyme involved in the appearance of a nuclear metabolite of 6a-methyl progesterone (6MP) in mouse kidney but not in prostate-seminal vesicle. 6MP and progesterone competed for metabolism by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c6c22a794930717df3350d3915a934
https://doi.org/10.1080/07435808709023658

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Differences in the androgen response between two mouse species

Autor: P W, Houben, L P, Bullock, T O, Fox

Publikováno v: Biochemical genetics. 24(11-12)

Renal weight and beta-glucuronidase activity are two of several well-characterized androgen-responsive parameters in Mus musculus. A similar sexual dimorphism was not reported for a second mouse species, Mus caroli, however. Since this was not associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e4d093a7ad75c685178920afcee9e7d0
https://pubmed.ncbi.nlm.nih.gov/3800866

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