Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes

Autor: Eline M.P. Cremers, Theresia M. Westers, Canan Alhan, Claudia Cali, Heleen A. Visser-Wisselaar, Dana A. Chitu, Vincent H.J. van der Velden, Jeroen G. te Marvelde, Saskia K. Klein, Petra Muus, Edo Vellenga, Georgina E. de Greef, Marie-Cecile C.J.C. Legdeur, Pierre W. Wijermans, Marian J.P.L. Stevens-Kroef, Pedro da Silva-Coelho, Joop H. Jansen, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht

Publikováno v: Haematologica, Vol 102, Iss 2 (2017)

Flow cytometric analysis is a recommended tool in the diagnosis of myelodysplastic syndromes. Current flow cytometric approaches evaluate the (im)mature myelo-/monocytic lineage with a median sensitivity and specificity of ~71% and ~93%, respectively

Externí odkaz: https://doaj.org/article/ce60285c497d4c0a8b8092e8a4f0c35f

Extended follow up of high-dose melphalan and autologous stem cell transplantation after vincristine, doxorubicin, dexamethasone induction in amyloid light chain amyloidosis of the prospective phase II HOVON-41 study by the Dutch-Belgian Co-operative Trial Group for Hematology Oncology

Autor: Bouke P.C. Hazenberg, Alexandra Croockewit, Bronno van der Holt, Sonja Zweegman, Gerard M.J. Bos, Michel Delforge, Reinier A.P. Raymakers, Pieter Sonneveld, Edo Vellenga, Pierre W. Wijermans, Peter A. von dem Borne, Marinus H. van Oers, Okke de Weerdt, Fokje M. Spoelstra, Henk M. Lokhorst, for the Dutch-Belgian Cooperative Trial Group for Hematology Oncology (HOVON)

Publikováno v: Haematologica, Vol 100, Iss 5 (2015)

In a prospective multicenter phase II study, we evaluated the effect of three courses of vincristine, doxorubicin and dexamethasone followed by high-dose melphalan and autologous stem cell transplantation on an intention-to-treat basis. Sixty-nine ne

Externí odkaz: https://doaj.org/article/0df65f42af02439991a4cbb41a0d44b5

Efficacy of escalated imatinib combined with cytarabine in newly diagnosed patients with chronic myeloid leukemia

Autor: Wendy Deenik, Jeroen J.W.M. Janssen, Bronno van der Holt, Gregor E.G. Verhoef, Willem M. Smit, Marie José Kersten, Simon M.G.J. Daenen, Leo F. Verdonck, Augustin Ferrant, Anton V.M.B. Schattenberg, Pieter Sonneveld, Marinus van Marwijk Kooy, Shulamit Wittebol, Roelof Willemze, Pierre W. Wijermans, H. Berna Beverloo, Bob Löwenberg, Peter J.M. Valk, Gert J. Ossenkoppele, Jan J. Cornelissen

Publikováno v: Haematologica, Vol 95, Iss 6 (2010)

Background In order to improve the molecular response rate and prevent resistance to treatment, combination therapy with different dosages of imatinib and cytarabine was studied in newly diagnosed patients with chronic myeloid leukemia in the HOVON-5

Externí odkaz: https://doaj.org/article/52ff014faa724e5c9930e7aea97fd445

Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study

Autor: C.A. Uyl-de Groot, Z. Erjavec, E. (Vera) J. M. Mattijssen, Gerard Vreugdenhil, Kim M. Holtzer-Goor, Eduardus F. M. Posthuma, Simon Daenen, Peter C. Huijgens, P. W. Wijermans, W. G. Peters, H. Visser, M. R. Schaafsma, P. Joosten, S. Wittebol, M. H. J. Van Oers, K. G. van der Hem

Publikováno v: Quality of Life Research, 24(12), 2895-2906. Springer Netherlands
Quality of Life Research, 24(12), 2895-2906. SPRINGER
Holtzer-Goor, K M, Schaafsma, M R, Joosten, P, Posthuma, E F M, Wittebol, S, Huijgens, P C, Mattijssen, E J M, Vreugdenhil, G, Visser, H, Peters, W G, Erjavec, Z, Wijermans, P W, Daenen, S M G J, van der Hem, K G, van Oers, M H J & Uyl-de Groot, C A 2015, ' Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study ', Quality of Life Research, vol. 24, no. 12, pp. 2895-2906 . https://doi.org/10.1007/s11136-015-1039-y
Quality of Life Research, 24(12), 2895-2906. Springer, Cham
Quality of Life Research
Quality of life research, 24(12), 2895-2906. Springer Netherlands

Purpose To describe the health-related quality of life (HRQoL) of an unselected population of patients with chronic lymphocytic leukaemia (CLL) including untreated patients. Methods HRQoL was measured by the EORTC QLQ-C30 including the CLL16 module,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7058cbb1613db4d1a60c05ddf2daf4
https://doi.org/10.1007/s11136-015-1039-y

Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40

Autor: Vera Mattijssen, Anita W. Rijneveld, Bart J. Biemond, P. W. Wijermans, Hilde Demuynck, F. M. Spoelstra, M. C. J. C. Legdeur, Roelof Willemze, O. de Weerdt, B. van der Holt, S. Wittebol, Johan Maertens, P. Muus, Simon Daenen, Jan J. Cornelissen, A. W. Dekker, Gert J. Ossenkoppele

Publikováno v: Leukemia, 25, 1697-703
Rijneveld, A W, van der Holt, B, Daenen, S M G J, Biemond, B J, de Weerdt, O, Muus, P, Maertens, J, Mattijssen, V, Demuynck, H, Legdeur, M C J C, Wijermans, P W, Wittebol, S, Spoelstra, F M, Dekker, A W, Ossenkoppele, G J, Willemze, R & Cornelissen, J J 2011, ' Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40 ', Leukemia, vol. 25, no. 11, pp. 1697-1703 . https://doi.org/10.1038/leu.2011.141
Leukemia, 25(11), 1697-1703. Nature Publishing Group
Leukemia, 25, 11, pp. 1697-703

Event-free survival (EFS) at 5 years in pediatric acute lymphoblastic leukemia (ALL) is 480%. Outcome in adult ALL is still unsatisfactory, which is due to less cumulative dosing of chemotherapy and less strict adherence to timing of successive cycle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ee4ad615727f0bde616a19c364d3e2
https://doi.org/10.1038/leu.2011.141