Zobrazeno 1 - 10
of 697
pro vyhledávání: '"P W, O'Toole"'
Autor:
Lu Yao, Hannah Devotta, Junhui Li, Nonhlanhla Lunjani, Corinna Sadlier, Aonghus Lavelle, Werner C. Albrich, Jens Walter, Paul W. O’Toole, Liam O’Mahony
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and risk of long COVID has been associated with the depletion or over-abundance of specific taxa within the gut microbiome. However, the microbial mechanisms me
Externí odkaz:
https://doaj.org/article/0c433fbe031448d99592a443e42591ca
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Irritable bowel syndrome (IBS) is a prevalent disorder of gut‐brain interaction without a reliable cure. Evidence suggests that an alteration of the gut microbiome may contribute to IBS pathogenesis, motivating the development of microbiom
Externí odkaz:
https://doaj.org/article/c7f310bd542f4080801b29a4749a9d6a
Autor:
Paul W. O'Toole
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract The human gut microbiome is a modifier of the risk for many non‐communicable diseases throughout the lifespan. In ageing, the effect of the microbiome appears to be more pronounced because of the lower physiological reserve. Microbial meta
Externí odkaz:
https://doaj.org/article/94fd97532ecf41bfa8f9a8244ba52ab5
Autor:
Liam H. Walsh, Samuel Breselge, José Guilherme Prado Martin, Mairéad Coakley, Eimear Ferguson, Aimee Stapleton, Fiona Crispie, Paul W. O'Toole, Paul D. Cotter
Publikováno v:
Journal of Microbiology & Biology Education, Vol 25, Iss 1 (2024)
ABSTRACTMicroorganisms are ubiquitous in nature and are central to human, animal, environmental, and planetary health. They play a particularly important role in the food chain and the production of high-quality, safe, and health-promoting foods, esp
Externí odkaz:
https://doaj.org/article/b1838dc1e71c43ee8bff4fbb3b976c4e
Autor:
Min Yap, Orla O'Sullivan, Paul W. O'Toole, Jeremiah J. Sheehan, Mark A. Fenelon, Paul D. Cotter
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTSeason and location have previously been shown to be associated with differences in the microbiota of raw milk, especially in milk from pasture-based systems. Here, we further advance research in this area by examining differences in the raw
Externí odkaz:
https://doaj.org/article/3425e5d76e30465397bd7860e647de21
Autor:
Rachel Mac Cann, Ellen Newman, Declan Devane, Caroline Sabin, Aoife G Cotter, Alan Landay, Paul W O'Toole, Patrick W Mallon
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0308859 (2024)
BackgroundEffective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH). However, this population is now experiencing accelerated age-related comorbidities, contributed to by chronic immune activation and inflammati
Externí odkaz:
https://doaj.org/article/0ac45470ee524e909fdb73383ef15e51
Autor:
Huimin Ye, Tarini S. Ghosh, Cara M. Hueston, Klara Vlckova, Anna V. Golubeva, Niall P. Hyland, Paul W. O’Toole
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTHuman aging is characterized by gut microbiome alteration and differential loss of gut commensal species associated with the onset of frailty. The administration of cultured commensal strains to replenish lost taxa could potentially promote h
Externí odkaz:
https://doaj.org/article/ca342f00e4ba4708bf0d6484736245cc
Autor:
Junhui Li, Tarini Shankar Ghosh, Rachel MacCann, Patrick Mallon, Colin Hill, Lorraine Draper, David Schult, Liam J. Fanning, Robert Shannon, Corinna Sadlier, Mary Horgan, Liam O’Mahony, Paul W. O’Toole
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTAlthough many recent studies have examined associations between the gut microbiome and COVID-19 disease severity in individual patient cohorts, questions remain on the robustness across international cohorts of the biomarkers they reported. H
Externí odkaz:
https://doaj.org/article/cfd8ff0c874641adacea00c18964fd43
Autor:
Peter Cronin, Siobhan McCarthy, Cian Hurley, Tarini Shankar Ghosh, Jakki C. Cooney, Ann-Marie Tobin, Michelle Murphy, Eibhlís M. O’Connor, Fergus Shanahan, Paul W. O’Toole
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThe chronic inflammatory skin disease Hidradenitis suppurativa (HS) is strongly associated with Crohn’s Disease (CD). HS and CD share clinical similarities and similar inflammatory pathways are upregulated in both conditions. Increased
Externí odkaz:
https://doaj.org/article/f6100021721f40fab2505dee5913ea94
Autor:
Liam H. Walsh, Mairéad Coakley, Aaron M. Walsh, Fiona Crispie, Paul W. O’Toole, Paul D. Cotter
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108004- (2023)
Summary: A comprehensive metagenomics-based investigation of the microorganisms present within milk kefir communities from across the globe was carried out with a view to defining the milk kefir pan-metagenome, including details relating to core and
Externí odkaz:
https://doaj.org/article/9a1044c99cbe4dbc84c8915ff0475dc6