Zobrazeno 1 - 10
of 69
pro vyhledávání: '"P W, Cook"'
Autor:
Abdullah A. Al-Omari, Katherine W. Cook, Peter Symonds, Anne Skinner, Alissa Wright, Yaling Zhu, Vincent L. Coble, Omar J. Mohammed, Ruhul H. Choudhury, Nazim Uddin, Priscilla Ranglani, Adrian Parry, Sally E. Adams, Geoffrey M. Lynn, Lindy G. Durrant, Victoria A. Brentville
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Stresses within the tumour microenvironment can mediate post-translational modifications of self-proteins. Homocitrullination is the conversion of lysine to homocitrulline which generates neoepitopes and bypasses self-tolerance. In this stud
Externí odkaz:
https://doaj.org/article/23239a3c715b458689ed217f6fc0ec62
Autor:
Julia Bajsert, Valérie De Glas, Emilie Faway, Catherine Lambert de Rouvroit, Miguel Pérez-Aso, Paul W. Cook, Yves Poumay
Publikováno v:
JID Innovations, Vol 4, Iss 5, Pp 100298- (2024)
The Reconstructed Human Epidermis (RHE) model derived from epidermal keratinocytes offers an ethical and scientific alternative to animal experimentation, particularly in cutaneous toxicology and dermatological research, where the elimination of anim
Externí odkaz:
https://doaj.org/article/3c1eae6cb5be494cb4e0d23859db43a7
Autor:
Jeremy W. Prokop, Sheryl Alberta, Martin Witteveen-Lane, Samantha Pell, Hosam A. Farag, Disha Bhargava, Robert M. Vaughan, Austin Frisch, Jacob Bauss, Humza Bhatti, Sanjana Arora, Charitha Subrahmanya, David Pearson, Austin Goodyke, Mason Westgate, Taylor W. Cook, Jackson T. Mitchell, Jacob Zieba, Matthew D. Sims, Adam Underwood, Habiba Hassouna, Surender Rajasekaran, Maximiliano A. Tamae Kakazu, Dave Chesla, Rosemary Olivero, Adam J. Caulfield
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1863 (2024)
As of 2024, SARS-CoV-2 continues to propagate and drift as an endemic virus, impacting healthcare for years. The largest sequencing initiative for any species was initiated to combat the virus, tracking changes over time at a full virus base-pair res
Externí odkaz:
https://doaj.org/article/985421ef6f7e4d43a817c091c93598f7
Autor:
Krista Hammaker, Nathaniel Weathington, Joseph Maroon, Lawton W. Tang, Brian Donohue, Rachel Yehuda, Kenneth M. Ford, Myro Figura, Ben Kelmendi, Belinda Tan, Matthew W. Cook, Steven D. Factor, Laura Lagano, Henry Patrick Driscoll, Adam S. Howe, EunBit G. Cho, David M. Rabin
Publikováno v:
Harm Reduction Journal, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background The opioid crisis continues in full force, as physicians and caregivers are desperate for resources to help patients with opioid use and chronic pain disorders find safer and more accessible non-opioid tools. Main body The purpose
Externí odkaz:
https://doaj.org/article/6498c0fadc174fdc9c9bc45fa9de73be
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/37d3967b32554166ad9f8807d0eb6ce4
Publikováno v:
Heritage, Vol 6, Iss 2, Pp 928-945 (2023)
This study presents preliminary results from recent bathymetric LiDAR-guided surveys of submerged archaeological landscapes in the Apalachee Bay off the coast of Florida. We show how bathymetric LiDAR can re-identify previously recorded archaeologica
Externí odkaz:
https://doaj.org/article/3ddb51bfd9bb43448511efb76ebf954d
Autor:
Lei Zhu, Brandon Tan, Selina S. Dwight, Brendan Beahm, Matt Wilsey, Brett E. Crawford, Becky Schweighardt, Jennifer W. Cook, Thomas Wechsler, William F. Mueller
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 259-271 (2022)
N-glycanase 1 (NGLY1) Deficiency is a progressive, ultra-rare, autosomal recessive disorder with no approved therapy and five core clinical features: severe global developmental delay, hyperkinetic movement disorder, elevated liver transaminases, ala
Externí odkaz:
https://doaj.org/article/fc8806dc850d435e8186ae57cbee6eca
Autor:
Ian Pike, Victoria A Brentville, Peter Symonds, Katherine W Cook, Lindy G Durrant, Sabaria Shah, Samantha J Paston, Juliane Weißer, Anne Skinner, Abdullah Al Omari
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Post-translational modification of proteins has the potential to alter the ability of T cells to recognize major histocompatibility complex (MHC) class -I and class-II restricted antigens, thereby resulting in altered immune responses. One
Externí odkaz:
https://doaj.org/article/342d5a87314b4e2e86c9b1772995e11a
Autor:
Jeffrey M. Noble, Le Chang, Dan Chen, Binglin Wang, Raymond N. Dominey, Daniel W. Cook, Justina M. Burns, Rodger W. Stringham, Flavio S. P. Cardoso, David R. Snead
Publikováno v:
SynOpen, Vol 06, Iss 04, Pp 258-262 (2022)
An efficient method to prepare enantiopure (S)-glycidyl pivalate from (R)-epichlorohydrin and pivalic acid is reported. This work provides an alternative to the synthesis of this important building block from readily available and inexpensive materia
Externí odkaz:
https://doaj.org/article/bb4ad47317344ca795564b12813552d3
Autor:
Kristine A. Lacek, Benjamin L. Rambo-Martin, Dhwani Batra, Xiao-yu Zheng, Norman Hassell, Hitoshi Sakaguchi, Thomas Peacock, Natalie Groves, Matthew Keller, Malania M. Wilson, Mili Sheth, Morgan L. Davis, Mark Borroughs, Jonathan Gerhart, Samuel S. Shepard, Peter W. Cook, Justin Lee, David E. Wentworth, John R. Barnes, Rebecca Kondor, Clinton R. Paden
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1442-1445 (2022)
To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta–Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and va
Externí odkaz:
https://doaj.org/article/5e8324ff95a14c0798f9d40af5b9161c