Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P W, Baas"'
Autor:
D. T. Robson, A. C. W. Baas
Publikováno v:
Earth Surface Dynamics, Vol 12, Pp 1205-1226 (2024)
In this work, we simulate barchan swarms using the Two-Flank Agent-Based Model and investigate how changes to model parameters and environmental drivers lead to different swarm dynamics. In particular, we explore how the parameter qshift, which contr
Externí odkaz:
https://doaj.org/article/1353f6544c914102b55099bef3070344
Autor:
Dominic T. Robson, Andreas C. W. Baas
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 19, Pp n/a-n/a (2023)
Abstract We introduce a novel agent‐based model for simulating interactions between migrating barchan dunes. A new two‐flank representation of barchans allows modeling of bedform asymmetries that are intrinsic to collision dynamics but have not b
Externí odkaz:
https://doaj.org/article/7a6bf6790bf4433e9d5824363dcd5388
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Approximately 30% of the veterans who fought in the 1991 Gulf War (GW) suffer from a disease called Gulf War Illness (GWI), which encompasses a constellation of symptoms including cognitive deficits. A coalescence of evidence indicates that GWI was c
Externí odkaz:
https://doaj.org/article/c86efc5bedb04cb8bf0b05fbd4b4c1fd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Central axons have limited regenerative ability following injury. Here, the authors show that chronic activation of DRG neurons results in highly dynamic microtubules at the distal axons and enhanced axonal regrowth and synaptogenesis in the spinal c
Externí odkaz:
https://doaj.org/article/29dfd0fe65224658b1b222872c7de523
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Among the various chemicals that are commonly used as pesticides, organophosphates (OPs), and to a lesser extent, carbamates, are most frequently associated with adverse long-term neurological consequences. OPs and the carbamate, pyridostigmine, used
Externí odkaz:
https://doaj.org/article/94b176c2ce764033bd8fdacca1871263
Publikováno v:
Brain Sciences, Vol 11, Iss 8, p 1081 (2021)
Mutations of the SPAST gene that encodes the microtubule-severing enzyme called spastin are the chief cause of Hereditary Spastic Paraplegia. Growing evidence indicates that pathogenic mutations functionally compromise the spastin protein and endow i
Externí odkaz:
https://doaj.org/article/8bd00e10894342009908b7bc0b2a3d23
Autor:
Anand N. Rao, Ankita Patil, Mark M. Black, Erin M. Craig, Kenneth A. Myers, Howard T. Yeung, Peter W. Baas
Publikováno v:
Cell Reports, Vol 19, Iss 11, Pp 2210-2219 (2017)
Axonal microtubules are predominantly organized into a plus-end-out pattern. Here, we tested both experimentally and with computational modeling whether a motor-based polarity-sorting mechanism can explain this microtubule pattern. The posited mechan
Externí odkaz:
https://doaj.org/article/81c6469ff78547929630d2c2a225e1d4
Autor:
Lanfranco Leo, Wenqian Yu, Mitchell D’Rozario, Edward A. Waddell, Daniel R. Marenda, Michelle A. Baird, Michael W. Davidson, Bin Zhou, Bingro Wu, Lisa Baker, David J. Sharp, Peter W. Baas
Publikováno v:
Cell Reports, Vol 12, Iss 11, Pp 1723-1730 (2015)
Individual microtubules (MTs) in the axon consist of a stable domain that is highly acetylated and a labile domain that is not. Traditional MT-severing proteins preferentially cut the MT in the stable domain. In Drosophila, fidgetin behaves in this f
Externí odkaz:
https://doaj.org/article/b42345f0e8274bfb903db081e780ff8a
Autor:
Peter W Baas, Andrew J Matamoros
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 6, Pp 845-849 (2015)
Microtubules have been identified as a powerful target for augmenting regeneration of injured adult axons in the central nervous system. Drugs that stabilize microtubules have shown some promise, but there are concerns that abnormally stabilizing mic
Externí odkaz:
https://doaj.org/article/c68cdfd8569d498c8edecd0d8373df6f
Publikováno v:
Journal of neurocytology. 30(11)
When cultured on polylysine, rat sympathetic neurons extend modest lamellae which contain a mass of relatively short non-aligned microtubules. Microtubules display movements, but these movements do not result in any obvious alterations in the overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ecb28d14ec53f664f5351a4cf3ce603
https://pubmed.ncbi.nlm.nih.gov/12373094
https://pubmed.ncbi.nlm.nih.gov/12373094