Zobrazeno 1 - 10
of 18
pro vyhledávání: '"P V Steart"'
Publikováno v:
Neuropathology and Applied Neurobiology. 29:106-117
Accumulation of amyloid beta (Abeta) in the extracellular spaces of the cerebral cortex and in blood vessel walls as cerebral amyloid angiopathy is a characteristic of Alzheimer's disease (AD) and the ageing human brain. Studies in animals suggest th
Publikováno v:
Neuropathology and Applied Neurobiology. 21:352-361
Apoptosis is an important determinant of tumour growth which can be regulated by the bcl-2 and p53 genes. This study examines the relationship between apoptosis, growth fraction (Ki-67 immunolabelling index), and accumulation of the bcl-2 and p53 pro
Publikováno v:
Neuropathology and Applied Neurobiology. 21:121-129
Perivascular cells (PVCs) form an immunophenotypically defined population that plays an important scavenging role in the perivascular fluid drainage pathways in the rat brain; such cells may also act as antigen-presenting cells. The present study tes
Publikováno v:
Acta Neuropathologica. 85:646-652
Perivascular cells in the rat brain are an immunophenotypically defined group of cells which can be identified by their expression of the ED2 antigen. The present study investigates the role of perivascular cells as scavengers in the perivascular spa
Publikováno v:
The Journal of Pathology. 168:383-386
Many human cancers are characterized by mutations of p53, a nuclear phosphoprotein which controls elements of the cell cycle. Turnover of p53 in normal cells is rapid, and the minute quantities of protein that are usually present are not detected by
Publikováno v:
Neuropathology and Applied Neurobiology. 17:177-187
'Gliosarcomas' have long been considered to be mixed gliomas and sarcomas. The present study failed to define criteria which clearly delineate 'gliosarcomas' from glioblastoma multiforme and suggests that 'gliosarcomas' should be considered as spindl
Publikováno v:
Eye. 4:42-57
The structure of the lamina cribrosa was studied by histological and immunocytochemical techniques and by scanning and transmission electron microscopy in four eyes removed surgically and in 21 normal eyes obtained from an eye bank. Dissection of the
Publikováno v:
Neuropathology and applied neurobiology. 29(2)
Accumulation of amyloid beta (Abeta) in the extracellular spaces of the cerebral cortex and in blood vessel walls as cerebral amyloid angiopathy is a characteristic of Alzheimer's disease (AD) and the ageing human brain. Studies in animals suggest th
Publikováno v:
Neuropathology and applied neurobiology. 21(2)
The p53 tumour suppressor gene contributes to the regulation of DNA repair and the initiation of apoptosis. Mutations of this gene and nuclear accumulation of its protein product are features of a large variety of tumours. A histological spectrum of
Publikováno v:
Neuropathology and applied neurobiology. 20(2)