Zobrazeno 1 - 4
of 4
pro vyhledávání: '"P V, Newcomb"'
Publikováno v:
International journal of cancer. 88(3)
Neoplastic transformation is characterised by an imbalance in favour of cell growth over programmed cell death (apoptosis). The tumour-suppressor gene p53, responsible for maintaining cell-cycle control, is mutated in the majority of human cancers. L
Publikováno v:
International journal of cancer. 88(3)
Variability in response to chemotherapy is poorly understood. Paclitaxel-induced apoptosis was assessed in human Hs578T breast cancer cells, using the MTT assay, cell counting, morphological features and flow cytometry. Pre-dosing cells with non-glyc
Publikováno v:
Journal of cellular biochemistry. 75(4)
We have demonstrated previously that insulin-like growth factor binding protein (IGFBP)-3 alone has little growth inhibitory effect on Hs578T human breast cancer cells, but that it can dramatically accentuate the apoptotic response to the physiologic
An immunohistochemical and prognostic evaluation of cathepsin D expression in 105 bladder carcinomas
Publikováno v:
The Journal of urology. 154(1)
Cathepsin D is a widely expressed aspartyl lysosomal protease. Clinical studies in several tumor types have shown a strong correlation between cathepsin D expression and tumor progression. In breast carcinoma, its expression is an independent prognos