Optimization and evaluation of nebivolol hydrochloride loaded transferosomes using Box-Behnken experimental design

Autor: P V Shelke, Punit R Rachh, Someshwar Mankar, Saurin Amin, Deepak Jain

Publikováno v: Journal of Applied Pharmaceutical Research, Vol 12, Iss 4, Pp 124-138 (2024)

Background: This study optimizes and evaluates transferosomes containing Nebivolol Hydrochloride to enhance the drug's bioavailability and therapeutic efficacy. Ultra-deformable vesicles called transferosomes help to increase drug administration via

Externí odkaz: https://doaj.org/article/5f43b1dd52684497b0b12fe945b3e38c

Assessment of bleeding events in patients receiving DOACs with or without statins to treat venous thromboembolism: insights from the RIETE registry

Autor: Dominique Farge-bancel, R Marqués, M Ortiz, Paolo Prandoni, J Roa, Manuel Monreal, F Couturaud, J Gutierrez, J Pagan, Peter Verhamme, A Aujayeb, Laurent Bertoletti, P Verhamme, M Monreal, S Fonseca, S Pinto, S Soler, A Lorenzo, R Lecumberri, R Otero, P DI MICCO, F Rivera-Cívico, A Molino, P Suchon, C Grange, JA Caprini, J Osorio, Henri Bounameaux, R Valle, F Negro, A Tufano, Remedios Otero, Aitor Ballaz, G Kenet, I Francisco, F Uresandi, G Barillari, Marijan Bosevski, F García-Bragado, E Grau, D Jiménez, A Maestre, A Visonà, J Criado, R Chopard, I Weinberg, M Lumbierres, B Leclercq, H Bounameaux, Farid Rashidi, Abílio Reis, Lucia Mazzolai, P Llamas, MJ Núñez-Fernández, F Dentali, O Espitia, C Siniscalchi, Rosaria Del Giorno, Sanjiv Keller, Carmine Siniscalchi, Luciano Lopez-Jimenez, Ana Cristina Montenegro, Benjamin Brenner, Raquel Barb, Pierpaolo Di Micco, Sebastian Schellong, Inna Tzoran, Radovan Malý, Joseph A. Caprini, Hanh My Bui, MD Adarraga, A Alberich-Conesa, J Aibar, A Alda-Lozano, J Alfonso, C Amado, M Angelina-García, JI Arcelus, A Ballaz, R Barba, C Barbagelata, M Barrón, B Barrón-Andrés, F Beddar-Chaib, A Blanco-Molina, JC Caballero, J Carrillo-Alonso, G Castellanos, L Chasco, C De Ancos, J Del Toro, P Demelo-Rodríguez, C De Juana-Izquierdo, MC Díaz-Pedroche, JA Díaz-Peromingo, A Dubois-Silva, JC Escribano, C Falgá, AI Farfán-Sedano, C Fernández-Aracil, C Fernández-Capitán, B Fernández-Jiménez, JL Fernández-Reyes, MA Fidalgo, C Gabara, F Galeano-Valle, C García-González, A García-Ortega, O Gavín-Sebastián, MA Gil-De Gómez, A Gil-Díaz, C Gómez-Cuervo, A González-Munera, L Guirado, L Hernández-Blasco, L Jara-Palomares, MJ Jaras, I Jou, MD Joya, JL Lobo, L López-Jiménez, P López-Miguel, H López-Brull, JJ López-Núñez, A López-Ruiz, JB LópezSáez, O Madridano, PJ Marchena, M Marcos, M Martín del Pozo, F Martín-Martos, R Martínez-Prado, JM Maza, E Mena, MI Mercado, J Moisés, MV Morales, MS Navas, JA Nieto, M Olid, L Ordieres-Ortega, S Otálora, N Pacheco-Gómez, AC Palomeque, E Paredes, P Parra-Caballero, P Parra-Rosado, JM Pedrajas, C Pérez-Ductor, M Pérez-Pinar, MA Pérez-Jacoiste, ML Peris, ML Pesce, JA Porras, R Puchades, A Rodríguez-Cobo, M Romero-Brugera, P Ruiz-Artacho, N Ruiz-Giménez, J Ruiz-Ruiz, G Salgueiro, T Sancho, V Sendín, P Sigüenza, A Steinherr, S Suárez-Fernández, R Tirado, A TorrentsVilar, MI Torres, J Trujillo-Santos, JF Varona, A Villalobos, P Villares, C Ay, S Nopp, I Pabinger, C Van Edom, A Verstraete, Yoo HHB, AC Montenegro, SN Morales, J Hirmerova, R Malý, L Bertoletti, A BuraRiviere, J Catella, R Le Mao, I Mahé, F Moustafa, L Plaisance, G Sarlon-Bartoli, E Versini, S Schellong, B Brenner, I Tzoran, P Sadeghipour, F Rashidi, A Abenante, M Basaglia, M Bertoni, F Bilora, B Brandolin, M Ciammaichella, D Colaizzo, E Grandone, E Imbalzano, R Pesavento, A Poz, P Prandoni, B Taflaj, B Zalunardo, A Skride, D Kigitovica, J Meireles, M Bosevski, M Zdraveska, L Mazzolai, HM Bui

Publikováno v: BMJ Open, Vol 14, Iss 10 (2024)

Objective To evaluate the impact of coadministering statins with direct oral anticoagulants (DOACs) on the risk of major bleeding events in patients with venous thromboembolism (VTE).Design Observational cohort analysis based on a multicentre interna

Externí odkaz: https://doaj.org/article/783c0993cd8248e8891454a53ddc48b0

COMPARAÇÃO DO TESTE DE DESIALIZAÇÃO PLAQUETÁRIA EM PACIENTES COM PÚRPURAS IMUNES E TROMBOCITOPATIAS CONGÊNITAS

Autor: KNC Ziza, AMC Alves, MCAV Conrado, TCS Silva, C Gabe, P Villaça, V Rocha, A Mendrone-Junior, DL Júnior, J Bordin, CL Dinardo

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S621- (2024)

Introdução: As trombocitopatias congênitas como Trombastenia de Glanzmann (GT) e a Síndrome de Bernard-Soulier (BSS) são distúrbios hereditários raros provenientes de alterações quantitativas ou qualitativas da glicoproteína da membrana pla

Externí odkaz: https://doaj.org/article/0ff5f5139125493bb34dcb98d49025b6

Nanoparticles supplementation through foliar feed contributed to the growth and cocoon yield of silkworm (Bombyx mori)

Autor: SALEEMALI KANNIHALLI, S G RAYAR, C P MALLAPUR, P V PATIL, RAVIKUMAR HOSAMANI

Publikováno v: The Indian Journal of Agricultural Sciences, Vol 94, Iss 10 (2024)

An experiment was conducted during 2021–22 and 2022–23 at University of Agricultural Sciences, Dharwad, Karnataka to study the effect of metal nanoparticles on silkworm (Bombyx mori) growth and cocoon yield. The experiment was laid out in complet

Externí odkaz: https://doaj.org/article/f994889d54814b2f9e750fd195b15bf3

A study on early surgical complications in renal transplant recipients

Autor: J V S. Prakash, P V Thiruvarul, V Natarajan, S Vetrichandar, K V Arasi, Arun Kumar Paranjothi, P Dhineshkumar

Publikováno v: Indian Journal of Transplantation, Vol 18, Iss 1, Pp 27-37 (2024)

Introduction: Renal transplantation is one of the most effective treatment measures in patients with end-stage renal disease to improve their quality of life. However, postoperative surgical complications can be seen in 15% to 17% of cases, with sign

Externí odkaz: https://doaj.org/article/b61aedda7b4a4497bfd7ee09f8f7d1f7