Zobrazeno 1 - 10
of 103
pro vyhledávání: '"P T Andrews"'
Autor:
Henriette Kuehne, Janice M. Davis, LeeAnne Merewether, Matthew McQueen, Elizabeth Valentine, Glen Young, Benjamin T. Andrews, Dimitri Diaz, Karen J. Miller
Publikováno v:
Drugs in R&D, Vol 24, Iss 2, Pp 285-301 (2024)
Abstract Background Pegfilgrastim-cbqv/CHS-1701 (UDENYCA®) (hereafter referred to as pegfilgrastim-cbqv) was approved in 2018 by the US Food and Drug Administration as a biosimilar for pegfilgrastim (Neulasta®) (hereafter referred to as pegfilgrast
Externí odkaz:
https://doaj.org/article/270728c12700482c860574a900dcd29b
Autor:
Frazer I. Heinis, Shaheed Merani, Nicholas W. Markin, Kim F. Duncan, Michael J. Moulton, Lance Fristoe, William E. Thorell, Raechel A. Sherrick, Tami R. Wells, Matthew T. Andrews, Marian Urban
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 3, Pp 283-296 (2024)
Abstract Use of animal models in preclinical transplant research is essential to the optimization of human allografts for clinical transplantation. Animal models of organ donation and preservation help to advance and improve technical elements of sol
Externí odkaz:
https://doaj.org/article/8c094a62c7144b8f84fca917a34c0b53
Autor:
G. H. Miller, S. L. Pendleton, A. Jahn, Y. Zhong, J. T. Andrews, S. J. Lehman, J. P. Briner, J. H. Raberg, H. Bueltmann, M. Raynolds, Á. Geirsdóttir, J. R. Southon
Publikováno v:
Climate of the Past, Vol 19, Pp 2341-2360 (2023)
Most extant ice caps mantling low-relief Arctic Canada landscapes remained cold based throughout the late Holocene, preserving in situ bryophytes killed as ice expanded across vegetated landscapes. After reaching peak late Holocene dimensions ∼1900
Externí odkaz:
https://doaj.org/article/2bddb4b9f9264238939ca132d243cdbd
Autor:
J. P. Mulcahy, C. G. Jones, S. T. Rumbold, T. Kuhlbrodt, A. J. Dittus, E. W. Blockley, A. Yool, J. Walton, C. Hardacre, T. Andrews, A. Bodas-Salcedo, M. Stringer, L. de Mora, P. Harris, R. Hill, D. Kelley, E. Robertson, Y. Tang
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 1569-1600 (2023)
Many Coupled Model Intercomparison Project phase 6 (CMIP6) models have exhibited a substantial cold bias in the global mean surface temperature (GMST) in the latter part of the 20th century. An overly strong negative aerosol forcing has been suggeste
Externí odkaz:
https://doaj.org/article/e8ff5e5c9ce14dedb3a95307b107969d
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Mammalian hibernators undergo substantial changes in metabolic function throughout the seasonal hibernation cycle. We report here the polar metabolomic profile of white adipose tissue isolated from active and hibernating thirteen-lined ground squirre
Externí odkaz:
https://doaj.org/article/740d3f9186964e0e8d10b1d6fa0e264e
Autor:
Paula Rambarat, Emily K Zern, Dongyu Wang, Athar Roshandelpoor, Shahrooz Zarbafian, Elizabeth E Liu, Jessica K Wang, Jenna N McNeill, Carl T Andrews, Eugene V Pomerantsev, Nathaniel Diamant, Puneet Batra, Steven A Lubitz, Michael H Picard, Jennifer E Ho
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290553 (2023)
IntroductionThe classification and management of pulmonary hypertension (PH) is challenging due to clinical heterogeneity of patients. We sought to identify distinct multimorbid phenogroups of patients with PH that are at particularly high-risk for a
Externí odkaz:
https://doaj.org/article/3e93a39336ab410797bc3ee782c860bd
Autor:
Ming Jang Chua, Jiahui Tng, Eva Hesping, Gillian M. Fisher, Christopher D. Goodman, Tina Skinner-Adams, Darren Do, Andrew J. Lucke, Robert C. Reid, David P. Fairlie, Katherine T. Andrews
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss , Pp 118-127 (2021)
Malaria is caused by infection with Plasmodium parasites and results in significant health and economic impacts. Malaria eradication is hampered by parasite resistance to current drugs and the lack of a widely effective vaccine. Compounds that target
Externí odkaz:
https://doaj.org/article/5959954d7921430bae9d2c5c297af676
Autor:
T. Tang, D. Shindell, Y. Zhang, A. Voulgarakis, J.-F. Lamarque, G. Myhre, G. Faluvegi, B. H. Samset, T. Andrews, D. Olivié, T. Takemura, X. Lee
Publikováno v:
Atmospheric Chemistry and Physics, Vol 21, Pp 13797-13809 (2021)
For the radiative impact of individual climate forcings, most previous studies focused on the global mean values at the top of the atmosphere (TOA), and less attention has been paid to surface processes, especially for black carbon (BC) aerosols. In
Externí odkaz:
https://doaj.org/article/c5b73fc187a3474cb7f21a6f7a3ad1cd
Autor:
Anne E. Jennings, John T. Andrews
Publikováno v:
Arctic, Antarctic, and Alpine Research, Vol 53, Iss 1, Pp 212-216 (2021)
Externí odkaz:
https://doaj.org/article/545d1e81f861424783df1636d4481748
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 249-256 (2020)
The prevention and treatment of malaria requires a multi-pronged approach, including the development of drugs that have novel modes of action. Histone deacetylases (HDACs), enzymes involved in post-translational protein modification, are potential ne
Externí odkaz:
https://doaj.org/article/c65cbe77f8f5495ba8bbb913ad120199