Zobrazeno 1 - 10
of 33
pro vyhledávání: '"P T, Gill"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract RNA polymerase (RNAP) is emblematic of complex biological systems that control multiple traits involving trade-offs such as growth versus maintenance. Laboratory evolution has revealed that mutations in RNAP subunits, including RpoB, are fre
Externí odkaz:
https://doaj.org/article/d16934fc926045d6b0a15469f358e7af
Autor:
Viktor T. Gill, Gustav Stålhammar
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23447- (2024)
Purpose: To examine incidence, risk factors, and outcomes of cataract surgery after plaque brachytherapy for posterior uveal melanoma. Design: Retrospective interventional cohort study contrasted with general population data. Methods: All patients tr
Externí odkaz:
https://doaj.org/article/caca7c801afd4bb880c4af6acb5b57ea
Autor:
Arsenios Vlassis, Tanja L. Jensen, Marina Mohr, Dominika J. Jedrzejczyk, Xiangyou Meng, Gergo Kovacs, Martí Morera-Gómez, Andrea Barghetti, Sergi Muyo Abad, Roland F. Baumgartner, Kedar N. Natarajan, Lars K. Nielsen, Tanya Warnecke, Ryan T. Gill
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108287- (2023)
Summary: Discovery of genomic safe harbor sites (SHSs) is fundamental for multiple transgene integrations, such as reporter genes, chimeric antigen receptors (CARs), and safety switches, which are required for safe cell products for regenerative cell
Externí odkaz:
https://doaj.org/article/1ed7e3c6b32b4486a833882c76203d11
Publikováno v:
Journal of Applied Poultry Research, Vol 32, Iss 2, Pp 100268- (2023)
SUMMARY: Studies of broiler sales in Sub-Saharan Africa have mostly focused on West Africa, particularly Nigeria. Similar studies in countries like Rwanda are lacking. The absence of marketing and sales strategies is a major constraint to strengtheni
Externí odkaz:
https://doaj.org/article/4772ea5ad6dd40798c0ce26765faaa0a
Autor:
D. J. Jedrzejczyk, L. D. Poulsen, M. Mohr, N. D. Damas, S. Schoffelen, A. Barghetti, R. Baumgartner, B. T. Weinert, T. Warnecke, R. T. Gill
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract CRISPR-Cas12a systems are becoming an attractive genome editing tool for cell engineering due to their broader editing capabilities compared to CRISPR-Cas9 counterparts. As opposed to Cas9, the Cas12a endonucleases are characterized by a lac
Externí odkaz:
https://doaj.org/article/946f3a9ec4ed48dfb18674a7c61193ab
Autor:
Mamta Gupta, Matthew Wong, Kamran Jawed, Kamil Gedeon, Hannah Barrett, Marcelo Bassalo, Clifford Morrison, Danish Eqbal, Syed Shams Yazdani, Ryan T. Gill, Jiaqi Huang, Marc Douaisi, Jonathan Dordick, Georges Belfort, Mattheos A.G. Koffas
Publikováno v:
Metabolic Engineering Communications, Vol 15, Iss , Pp e00210- (2022)
The production of the biofuel, isobutanol, in E. coli faces limitations due to alcohol toxicity, product inhibition, product recovery, and long-term industrial feasibility. Here we demonstrate an approach of combining both in vivo with in vitro metab
Externí odkaz:
https://doaj.org/article/ac03648bb6c645638fbd2ddc4000accd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Regulatory networks respond to environmental and genetic perturbations by reprogramming metabolism. Here the authors screen a library of 82 regulators with 110,120 mutations to map the regulatory network of 4000 genes.
Externí odkaz:
https://doaj.org/article/600753d8182544abaa6cc9ffdf23ce81
Autor:
Alaksh Choudhury, Jacob A Fenster, Reilly G Fankhauser, Joel L Kaar, Olivier Tenaillon, Ryan T Gill
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 3, Pp 1-22 (2020)
Abstract Deep mutational scanning can provide significant insights into the function of essential genes in bacteria. Here, we developed a high‐throughput method for mutating essential genes of Escherichia coli in their native genetic context. We us
Externí odkaz:
https://doaj.org/article/5f2e06ad113d433aa65e1e649e871ef6
Autor:
R. M. Liu, L. L. Liang, E. Freed, H. Chang, E. Oh, Z. Y. Liu, A. Garst, C. A. Eckert, R. T. Gill
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
CRISPR-Cas systems have well characterized, modular structures. Here the authors use that architecture to design a Cas12a library of 560 synthetic chimeras, with altered PAM preferences and specificities.
Externí odkaz:
https://doaj.org/article/b3426a5c4a194f89b3f9de6d909729e5
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