Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P T, Clements"'
ML-GAP: machine learning-enhanced genomic analysis pipeline using autoencoders and data augmentation
Autor:
Melih Agraz, Dincer Goksuluk, Peng Zhang, Bum-Rak Choi, Richard T. Clements, Gaurav Choudhary, George Em Karniadakis
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe advent of RNA sequencing (RNA-Seq) has significantly advanced our understanding of the transcriptomic landscape, revealing intricate gene expression patterns across biological states and conditions. However, the complexity and volume
Externí odkaz:
https://doaj.org/article/47840e320b1f4afaaecb8f10ac3db67a
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 9, Pp n/a-n/a (2024)
Abstract Estimating an earthquake's magnitude and location may not be necessary to predict shaking in real time; instead, wavefield‐based approaches predict shaking with few assumptions about the seismic source. Here, we introduce GRAph Prediction
Externí odkaz:
https://doaj.org/article/9555cf02e19c4c5885ea8c9f76a818b0
Autor:
Peng Zhang, Denielli Da Silva Goncalves Bos, Alexander Vang, Julia Feord, Danielle J. McCullough, Alexsandra Zimmer, Natalie D'Silva, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Reduced exercise capacity in pulmonary hypertension (PH) significantly impacts quality of life. However, the cause of reduced exercise capacity in PH remains unclear. The objective of this study was to investigate whether intrinsic skeletal
Externí odkaz:
https://doaj.org/article/121e8e70e2a144189447e92323cadc38
Publikováno v:
Geoscience Communication, Vol 5, Pp 289-306 (2022)
Video games now comprise the largest sector of the media entertainment industry. Hundreds of video games, spanning a huge variety of genres and platforms, use extinct animals and/or palaeontological themes as a basis for their gameplay. Because of
Externí odkaz:
https://doaj.org/article/3442d1dc20ca477e884ca1f94f4da0a4
Autor:
H. S. Grantham, A. Duncan, T. D. Evans, K. R. Jones, H. L. Beyer, R. Schuster, J. Walston, J. C. Ray, J. G. Robinson, M. Callow, T. Clements, H. M. Costa, A. DeGemmis, P. R. Elsen, J. Ervin, P. Franco, E. Goldman, S. Goetz, A. Hansen, E. Hofsvang, P. Jantz, S. Jupiter, A. Kang, P. Langhammer, W. F. Laurance, S. Lieberman, M. Linkie, Y. Malhi, S. Maxwell, M. Mendez, R. Mittermeier, N. J. Murray, H. Possingham, J. Radachowsky, S. Saatchi, C. Samper, J. Silverman, A. Shapiro, B. Strassburg, T. Stevens, E. Stokes, R. Taylor, T. Tear, R. Tizard, O. Venter, P. Visconti, S. Wang, J. E. M. Watson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Mapping and quantifying degree of forest modification is critical to conserve and manage forests. Here the authors propose a new quantitative metric for landscape integrity and apply it to a global forest map, showing that less than half of the world
Externí odkaz:
https://doaj.org/article/f57a9baec4594adc9f1a1fb32d3d534b
Autor:
Alexander Vang, Denielli da Silva Gonçalves Bos, Ana Fernandez-Nicolas, Peng Zhang, Alan R. Morrison, Thomas J. Mancini, Richard T. Clements, Iuliia Polina, Michael W. Cypress, Bong Sook Jhun, Edward Hawrot, Ulrike Mende, Jin O-Uchi, Gaurav Choudhary
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and dysfunction and is associated with poor outcomes in pulmonary hypertension (PH). However, mechanisms and therapeutic strategies to mitigate RV fibrosis remain unrealiz
Externí odkaz:
https://doaj.org/article/c09c89c74fdf402a92c4c34005193f3d
Autor:
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexe
Externí odkaz:
https://doaj.org/article/cba774dd40ca4136a9cc616ff71451f7
Autor:
H. S. Grantham, A. Duncan, T. D. Evans, K. R. Jones, H. L. Beyer, R. Schuster, J. Walston, J. C. Ray, J. G. Robinson, M. Callow, T. Clements, H. M. Costa, A. DeGemmis, P. R. Elsen, J. Ervin, P. Franco, E. Goldman, S. Goetz, A. Hansen, E. Hofsvang, P. Jantz, S. Jupiter, A. Kang, P. Langhammer, W. F. Laurance, S. Lieberman, M. Linkie, Y. Malhi, S. Maxwell, M. Mendez, R. Mittermeier, N. J. Murray, H. Possingham, J. Radachowsky, S. Saatchi, C. Samper, J. Silverman, A. Shapiro, B. Strassburg, T. Stevens, E. Stokes, R. Taylor, T. Tear, R. Tizard, O. Venter, P. Visconti, S. Wang, J. E. M. Watson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-20999-7.
Externí odkaz:
https://doaj.org/article/89cf1c38f1fb42c0ab7949862c808757
Autor:
Shanna Hamilton, Radmila Terentyeva, Tae Yun Kim, Peter Bronk, Richard T. Clements, Jin O-Uchi, György Csordás, Bum-Rak Choi, Dmitry Terentyev
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
In a physiological setting, mitochondria increase oxidative phosphorylation during periods of stress to meet increased metabolic demand. This in part is mediated via enhanced mitochondrial Ca2+ uptake, an important regulator of cellular ATP homeostas
Externí odkaz:
https://doaj.org/article/afd9fd2a470d40ac8bbdb50a6b5dfb09
Autor:
Brittany A. Potz, Ashraf A. Sabe, Nassrene Y. Elmadhun, Richard T. Clements, Michael P. Robich, Neel R. Sodha, Frank W. Sellke
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
BackgroundInhibition of glycogen synthase kinase 3β (GSK‐3β) has been reported to be cardioprotective during stressful conditions. Methods and ResultsPigs were fed a high‐fat diet for 4 weeks to develop metabolic syndrome, then underwent placem
Externí odkaz:
https://doaj.org/article/21b9c6b2254e46218b741469886e574a