Zobrazeno 1 - 10
of 1 576
pro vyhledávání: '"P Stefanis"'
Autor:
Patrizia Tempora, Silvia D’Amico, Paula Gragera, Verena Damiani, Kamila Krol, Valentina Scaldaferri, Kirti Pandey, Shanzou Chung, Valeria Lucarini, Ezio Giorda, Marco Scarsella, Gabriele Volpe, Marco Pezzullo, Cristiano De Stefanis, Valentina D’Oria, Lorenzo De Angelis, Roberto Giovannoni, Maria Antonietta De Ioris, Ombretta Melaiu, Anthony W. Purcell, Franco Locatelli, Doriana Fruci
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Checkpoint immunotherapy unleashes tumor control by T cells, but it is undermined in non-immunogenic tumors, e.g. with low MHC class I expression and low neoantigen burden, such as neuroblastoma (NB). Endoplasmic reticulum aminope
Externí odkaz:
https://doaj.org/article/aa78a98ee3814c74b5bbaede290c72c8
Autor:
Virginia Di Paolo, Alessandro Paolini, Angela Galardi, Patrizia Gasparini, Loris De Cecco, Marta Colletti, Silvia Lampis, Salvatore Raieli, Cristiano De Stefanis, Evelina Miele, Ida Russo, Valentina Di Ruscio, Michela Casanova, Rita Alaggio, Andrea Masotti, Giuseppe Maria Milano, Franco Locatelli, Angela Di Giannatale
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-11 (2024)
Abstract Background Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma, with embryonal (ERMS) and alveolar (ARMS) representing the two most common histological subtypes. ARMS shows poor prognosis, being often metastatic at diagno
Externí odkaz:
https://doaj.org/article/dff12ffc5c95489591deecc318a9e227
Autor:
Christos Koros, Athina-Maria Simitsi, Nikolaos Papagiannakis, Anastasia Bougea, Roubina Antonelou, Ioanna Pachi, Evangelos Sfikas, Evangelia Stanitsa, Efthalia Angelopoulou, Vasilios C. Constantinides, Sokratis G. Papageorgiou, Constantin Potagas, Maria Stamelou, Leonidas Stefanis
Publikováno v:
Neurology International, Vol 16, Iss 4, Pp 833-844 (2024)
Introduction: Parkinson’s disease (PD) patients harboring recessive gene variants exhibit a distinct clinical phenotype with an early disease onset and relatively mild symptoms. Data concerning individualized therapy for autosomal recessive PD form
Externí odkaz:
https://doaj.org/article/8c7102d2e86c4bd3a8de511784e635a4
Autor:
Alex Hatzimanolis, Stefania Foteli, Lida-Alkisti Xenaki, Mirjana Selakovic, Stefanos Dimitrakopoulos, Ilias Vlachos, Ioannis Kosteletos, Rigas-Filippos Soldatos, Maria Gazouli, Stylianos Chatzipanagiotou, Nikos Stefanis
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract The tryptophan-metabolizing kynurenine pathway (KP) can be activated by enhanced inflammatory responses and has been implicated in the pathophysiology of schizophrenia. However, there is little evidence for KP dysregulation in the early cour
Externí odkaz:
https://doaj.org/article/321ed21632f34eb09b1c733ff43416bc
Autor:
Modestos Nakos Bimpos, Katerina Karali, Christine Antoniou, Dionysios Palermos, Maria Fouka, Anastasios Delis, Iason Tzieras, George Panagiotis Chrousos, Yassemi Koutmani, Leonidas Stefanis, Alexia Polissidis
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract A link between chronic stress and Parkinson’s disease (PD) pathogenesis is emerging. Ample evidence demonstrates that the presynaptic neuronal protein alpha-synuclein (asyn) is closely tied to PD pathogenesis. However, it is not known whet
Externí odkaz:
https://doaj.org/article/1cdab1fb36bb4bf49b13d9b72ea8d1e1
Autor:
Emily De Stefanis, Kemal Ramic, Judith Vidal, Youyang Zhao, Leighanne C. Gallington, Ryan Bedell, Li (Emily) Liu
Publikováno v:
Frontiers in Nuclear Engineering, Vol 3 (2024)
Ionic liquid materials are viable candidates as a heat transfer fluid (HTF) in a wide range of applications, notably within concentrated solar power (CSP) technology and molten salt reactors (MSRs). For next-generation CSP and MSR technologies that s
Externí odkaz:
https://doaj.org/article/77ef8c7d64dc4ea5aaa22c463f131716
Autor:
Maria Rita Braghini, Cristiano De Stefanis, Francesca Tiano, Aurora Castellano, Nicolo’ Cicolani, Marco Pezzullo, Valeria Tocco, Marco Spada, Rita Alaggio, Anna Alisi, Paola Francalanci
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundHepatoblastoma (HB) is the most common pediatric hepatic malignancy. Despite the progress in HB treatment, investigating HB pathomechanisms to optimize stratification and therapies remains a focal point to improve the outcome for high-risk
Externí odkaz:
https://doaj.org/article/8bd7b6029ac04845acc9a9b1c3c3f685
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Postmastectomy radiotherapy (PMRT) increases the risk for complications after breast reconstruction. The pathophysiological mechanism underlying this increased risk is not completely understood. The aim of this study was to examine if there
Externí odkaz:
https://doaj.org/article/eca2aecaad08446d90cc3fc0c57cd148
Autor:
Alex Hatzimanolis, Sarah Tosato, Mirella Ruggeri, Doriana Cristofalo, Leonidas Mantonakis, Lida-Alkisti Xenaki, Stefanos Dimitrakopoulos, Mirjana Selakovic, Stefania Foteli, Ioannis Kosteletos, Ilias Vlachos, Rigas-Filippos Soldatos, Nikos Nianiakas, Irene Ralli, Konstantinos Kollias, Angeliki-Aikaterini Ntigrintaki, Pentagiotissa Stefanatou, Robin M. Murray, Evangelos Vassos, Nikos C. Stefanis
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Insufficiency of vitamin D levels often occur in individuals with schizophrenia and first-episode psychosis (FEP). However, it is unknown whether this represents a biological predisposition, or it is essentially driven by illness-related alt
Externí odkaz:
https://doaj.org/article/4f0cc42bf6bd41188fa076dfa5bfa1be
Autor:
Silvia Pomella, Matteo Cassandri, Lucrezia D’Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S. Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R. Vakoc, Enrico Velardi, Beat W. Schafer, Ernesto Guccione, Susanne A. Gatz, Ajla Wasti, Marielle Yohe, Myron Ignatius, Concetta Quintarelli, Janet Shipley, Lucio Miele, Javed Khan, Peter J. Houghton, Francesco Marampon, Berkley E. Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Rhabdomyosarcomas (RMS) are pediatric mesenchymal-derived malignancies encompassing PAX3/7-FOXO1 Fusion Positive (FP)-RMS, and Fusion Negative (FN)-RMS with frequent RAS pathway mutations. RMS express the master myogenic transcription factor
Externí odkaz:
https://doaj.org/article/b02d638fdabc4c31acb1630b1acf4c96