Zobrazeno 1 - 10
of 45
pro vyhledávání: '"P Scott Hefty"'
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0304839 (2024)
Lyme disease is the leading tick-borne infection in the United States, caused by the pathogenic spirochete Borreliella burgdorferi, formerly known as Borrelia burgdorferi. Diderms, or bacteria with dual-membrane ultrastructure, such as B. burgdorferi
Externí odkaz:
https://doaj.org/article/54f776c13c504f978d348de064cfcba0
Autor:
Annette Fischer, Kelly S Harrison, Yesid Ramirez, Daniela Auer, Suvagata Roy Chowdhury, Bhupesh K Prusty, Florian Sauer, Zoe Dimond, Caroline Kisker, P Scott Hefty, Thomas Rudel
Publikováno v:
eLife, Vol 6 (2017)
Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling interface with the host cell. Here, we show that the chlamydial deubiquitinating enzyme (Cdu) 1 localizes in the inclusio
Externí odkaz:
https://doaj.org/article/b1e8d22bb1f04a32a1e99d57bb057a2f
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91760 (2014)
ChxR is an atypical two-component signal transduction response regulator (RR) of the OmpR/PhoB subfamily encoded by the obligate intracellular bacterial pathogen Chlamydia trachomatis. Despite structural homology within both receiver and effector dom
Externí odkaz:
https://doaj.org/article/bf6bdaea5c6e4a56a9cd21adf9095bfb
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76743 (2013)
Chlamydia trachomatis is maintained through a complex bi-phasic developmental cycle that incorporates numerous processes that are poorly understood. This is reflective of the previous paucity of genetic tools available. The recent advent of a method
Externí odkaz:
https://doaj.org/article/1b3b55a0aa724bf2b9d1ac376958929d
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Chlamydia bacteria are obligate intracellular organisms with a phylum-defining biphasic developmental cycle that is intrinsically linked to its ability to cause disease. The progression of the chlamydial developmental cycle is regulated by t
Externí odkaz:
https://doaj.org/article/9251d9ea4e5a4129996c5154b1f0210c
Autor:
Scott D. LaBrie, Zoë E. Dimond, Kelly S. Harrison, Srishti Baid, Jason Wickstrum, Robert J. Suchland, P. Scott Hefty
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Transposon mutagenesis is a widely applied and powerful genetic tool for the discovery of genes associated with selected phenotypes. Chlamydia trachomatis is a clinically significant, obligate intracellular bacterium for which many conventio
Externí odkaz:
https://doaj.org/article/b54a999996b046d1b1b1a981f120fac1
Autor:
Forrest Kwong, Robert J. Suchland, P. Scott Hefty, Kevin Hybiske, Katelyn R. Soules, Jacob Stanley, Srishti Baid, Yibing Wang, Scott D. LaBrie, Daniel D. Rockey, Zoe E. Dimond, Steven J. Carrell
Publikováno v:
Mol Microbiol
Chlamydia muridarum actively grows in murine mucosae and is a representative model of human chlamydial genital tract disease. In contrast, C. trachomatis infections in mice are limited and rarely cause disease. The factors that contribute to these di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f0425c464b7f3c3fb03a6556c56db4
https://doi.org/10.1111/mmi.14832
https://doi.org/10.1111/mmi.14832
Publikováno v:
Journal of microbiologybiology education. 23(2)
During the COVID-19 pandemic, universities across the globe quickly shifted to online education. Laboratory courses faced unique challenges and were forced to reevaluate learning objectives and identify creative projects to engage students online. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af12cfbf49b6970975849bc39d0d81f7
https://pubmed.ncbi.nlm.nih.gov/36061320
https://pubmed.ncbi.nlm.nih.gov/36061320
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
mBio
The factors that control the growth and infectious processes for Chlamydia are still poorly understood. This study used recently developed genetic tools to determine the regulon for one of the key transcription factors encoded by Chlamydia, sigma 54.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2928d424ce2ed29be9264144340503
https://journals.asm.org/doi/10.1128/mBio.01725-20
https://journals.asm.org/doi/10.1128/mBio.01725-20
Autor:
Yibing Wang, Robert J. Suchland, Debbie B. Kim, Kevin Hybiske, Zoe E. Dimond, Steven J. Carrell, P. Scott Hefty, Daniel D. Rockey
Publikováno v:
J Bacteriol
Lateral gene transfer (LGT) among Chlamydia trachomatis strains is common, in both isolates generated in the laboratory and those examined directly from patients. In contrast, there are very few examples of recent acquisition of DNA by any Chlamydia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ad16d9c6b8a3de856cfda1aa2d3fb5
https://doi.org/10.1128/jb.00365-19
https://doi.org/10.1128/jb.00365-19