Zobrazeno 1 - 10
of 29
pro vyhledávání: '"P S, Olofsson"'
Autor:
Assim Hayderi, Ashok K. Kumawat, Vladimir S. Shavva, Mats Dreifaldt, Birgitta Sigvant, Marcelo H. Petri, Björn Kragsterman, Peder S. Olofsson, Allan Sirsjö, Liza U. Ljungberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In atherosclerotic lesions, monocyte-derived macrophages are major source of interferon gamma (IFN-γ), a pleotropic cytokine known to regulate the expression of numerous genes, including the antiviral gene RSAD2. While RSAD2 was reported to
Externí odkaz:
https://doaj.org/article/6936c603b3404af69ead4ddf1e75c9a2
Autor:
William Lövfors, Rasmus Magnusson, Cecilia Jönsson, Mika Gustafsson, Charlotta S. Olofsson, Gunnar Cedersund, Elin Nyman
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Adipocyte signaling, normally and in type 2 diabetes, is far from fully understood. We have earlier developed detailed dynamic mathematical models for several well-studied, partially overlapping, signaling pathways in adipocytes. Still, thes
Externí odkaz:
https://doaj.org/article/cc9cf96f241a478db28a7eef0063ae70
Autor:
Osman Ahmed, April S. Caravaca, Maria Crespo, Wanmin Dai, Ting Liu, Qi Guo, Magdalena Leiva, Guadalupe Sabio, Vladimir S. Shavva, Stephen G. Malin, Peder S. Olofsson
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background The liver is an important immunological organ and liver inflammation is part of the pathophysiology of non-alcoholic steatohepatitis, a condition that may promote cirrhosis, liver cancer, liver failure, and cardiovascular disease.
Externí odkaz:
https://doaj.org/article/9da48cf905954ac6b4d0687c31190809
Autor:
Kim Eerola, Francesco Longo, Thomas M. Reinbothe, Jennifer E. Richard, Olesya T. Shevchouk, Lorena López-Ferreras, Devesh Mishra, Mohammed Asker, Johan Tolö, Caroline Miranda, Saliha Musovic, Charlotta S. Olofsson, Patrik Rorsman, Karolina P. Skibicka
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101614- (2022)
Objective: Pancreatic insulin was discovered a century ago, and this discovery led to the first lifesaving treatment for diabetes. While still controversial, nearly one hundred published reports suggest that insulin is also produced in the brain, wit
Externí odkaz:
https://doaj.org/article/76cbb955e0a1418aaf6153777cab1471
Autor:
Marco Bauzá-Thorbrügge, Elin Banke, Belén Chanclón, Eduard Peris, Yanling Wu, Saliha Musovic, Cecilia Jönsson, Peter Strålfors, Patrik Rorsman, Charlotta S. Olofsson, Ingrid Wernstedt Asterholm
Publikováno v:
Molecular Metabolism, Vol 63, Iss , Pp 101535- (2022)
Objective: Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) transports Ca2+ from the cytosol into the endoplasmic retitculum (ER) and is essential for appropriate regulation of intracellular Ca2+ homeostasis. The objective of this study was to test th
Externí odkaz:
https://doaj.org/article/4623a88199ba460394751310d53b7444
Autor:
Timir Datta-Chaudhuri, Theodoros Zanos, Eric H. Chang, Peder S. Olofsson, Stephan Bickel, Chad Bouton, Daniel Grande, Loren Rieth, Cynthia Aranow, Ona Bloom, Ashesh D. Mehta, Gene Civillico, Molly M. Stevens, Eric Głowacki, Christopher Bettinger, Martin Schüettler, Chris Puleo, Robert Rennaker, Saroj Mohanta, Daniela Carnevale, Silvia V. Conde, Bruno Bonaz, David Chernoff, Suraj Kapa, Magnus Berggren, Kip Ludwig, Stavros Zanos, Larry Miller, Doug Weber, Daniel Yoshor, Lawrence Steinman, Sangeeta S. Chavan, Valentin A. Pavlov, Yousef Al-Abed, Kevin J. Tracey
Publikováno v:
Bioelectronic Medicine, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract There is a broad and growing interest in Bioelectronic Medicine, a dynamic field that continues to generate new approaches in disease treatment. The fourth bioelectronic medicine summit “Technology targeting molecular mechanisms” took pl
Externí odkaz:
https://doaj.org/article/1f25ba976ecb456fa4058e80f71d9571
Publikováno v:
Bioelectronic Medicine, Vol 6, Iss 1, Pp 1-8 (2020)
Abstract Atherosclerosis is a multifactorial chronic inflammatory disease that underlies myocardial infarction and stroke. Efficacious treatment for hyperlipidemia and hypertension has significantly reduced morbidity and mortality in cardiovascular d
Externí odkaz:
https://doaj.org/article/2574091e357740c8a9679f06512e5fe3
Autor:
Ashok Kumar Kumawat, Mulugeta M. Zegeye, Geena Varghese Paramel, Roland Baumgartner, Anton Gisterå, Obed Amegavie, Sanna Hellberg, Hong Jin, April S. Caravaca, Leif Å. Söderström, Lindvi Gudmundsdotter, Fredrik Y. Frejd, Liza U. Ljungberg, Peder S. Olofsson, Daniel F. J. Ketelhuth, Allan Sirsjö
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The balance between pro- and anti-inflammatory cytokines released by immune and non-immune cells plays a decisive role in the progression of atherosclerosis. Interleukin (IL)-17A has been shown to accelerate atherosclerosis. In this study, we investi
Externí odkaz:
https://doaj.org/article/a008b8877cff40138fe7b07965ae20bc
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Crohn’s disease is a chronic, idiopathic condition characterized by intestinal inflammation and debilitating gastrointestinal symptomatology. Previous studies of inflammatory bowel disease (IBD), primarily in colitis, have shown reduced inflammatio
Externí odkaz:
https://doaj.org/article/cdd2d7d6cec44344b45cba39dbbfe01b
Autor:
Emily Brück, Jacob W. Larsson, Julie Lasselin, Matteo Bottai, Tatja Hirvikoski, Eva Sundman, Michael Eberhardson, Peter Sackey, Peder S. Olofsson
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-11 (2019)
Abstract Background Cognitive impairment and psychological distress are common in intensive care unit (ICU) survivors. Early identification of affected individuals is important, so intervention and treatment can be utilized at an early stage. Cogniti
Externí odkaz:
https://doaj.org/article/4b18a03f3bcc41839bbb097b084facbb