Zobrazeno 1 - 10
of 41
pro vyhledávání: '"P S, Nagarkatti"'
Autor:
Bryan Latrell Holloman, Kiesha Wilson, Alkeiver Cannon, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIndole-3-carbinol (I3C) is found in cruciferous vegetables and used as a dietary supplement. It is known to act as a ligand for aryl hydrocarbon receptor (AhR). In the current study, we investigated the role of AhR and the ability of I3C
Externí odkaz:
https://doaj.org/article/4698350205fc4d7f82129aeec4a0a887
Autor:
Marpe Bam, Xiaoming Yang, Jay P. Ginsberg, Allison E. Aiello, Monica Uddin, Sandro Galea, Prakash S. Nagarkatti, Mitzi Nagarkatti
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Post-traumatic stress disorder (PTSD), which frequently occurs in the aftermath of a psychologically traumatic event is characterized by heightened inflammation. People with PTSD also suffer from a number of comorbid clinical and behavioral
Externí odkaz:
https://doaj.org/article/db56856e3edd49a6859b249ee876742b
Autor:
Kathryn Miranda, William Becker, Philip B. Busbee, Nicholas Dopkins, Osama A. Abdulla, Yin Zhong, Jiajia Zhang, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104994- (2022)
Summary: While blockade of cannabinoid receptor 1 (CB1) has been shown to attenuate diet-induced obesity (DIO), its relative role in different cell types has not been tested. The current study investigated the role of CB1 in immune vs non-immune cell
Externí odkaz:
https://doaj.org/article/a427a91dc62d4f68ab15211c3c14d6bd
Autor:
Marpe Bam, Xiaoming Yang, Brandon P. Busbee, Allison E. Aiello, Monica Uddin, Jay P. Ginsberg, Sandro Galea, Prakash S. Nagarkatti, Mitzi Nagarkatti
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-15 (2020)
Abstract Background Posttraumatic stress disorder (PTSD) is a psychiatric disorder accompanied by chronic peripheral inflammation. What triggers inflammation in PTSD is currently unclear. In the present study, we identified potential defects in signa
Externí odkaz:
https://doaj.org/article/0d0fdfedff1f43c29ff5488f43c3bcc7
Autor:
Philip B. Busbee, Marpe Bam, Xiaoming Yang, Osama A. Abdulla, Juhua Zhou, Jay Paul (Jack) Ginsberg, Allison E. Aiello, Monica Uddin, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Post-traumatic stress disorder (PTSD) is a psychiatric disorder and patients diagnosed with PTSD often express other comorbid health issues, particularly autoimmune and inflammatory disorders. Our previous reports investigating peripheral blood monon
Externí odkaz:
https://doaj.org/article/b88282002d964614917b5f5e62b60d66
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Maintenance of intestinal homeostasis requires the integration of immunological and molecular processes together with environmental, diet, metabolic and microbial cues. Key to this homeostasis is the proper functioning of epithelial cells originating
Externí odkaz:
https://doaj.org/article/7422f643147544f5a0429714b9d50479
Autor:
William Becker, Haider Rasheed Alrafas, Kiesha Wilson, Kathryn Miranda, Courtney Culpepper, Ioulia Chatzistamou, Guoshuai Cai, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101504- (2020)
Summary: Intestinal disequilibrium leads to inflammatory bowel disease (IBD), and chronic inflammation predisposes to oncogenesis. Antigen-presenting dendritic cells (DCs) and macrophages can tip the equilibrium toward tolerance or pathology. Here we
Externí odkaz:
https://doaj.org/article/affab4cf134848f79316cc248de1a0f2
Autor:
Zinah Zamil Al-Ghezi, Narendra Singh, Pegah Mehrpouya-Bahrami, Philip Brandon Busbee, Mitzi Nagarkatti, Prakash S. Nagarkatti
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The Aryl Hydrocarbon Receptor (AhR) is a transcription factor that, when activated by ligand-binding, has been shown to regulate the immune response. Pertussis Toxin (PTX) is a virulence factor found in Bordetella pertussis, a human respiratory patho
Externí odkaz:
https://doaj.org/article/edf33e5edc5c4aa296379c972f2d881f
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Multiple sclerosis (MS) is a chronic and disabling disorder of the central nervous system (CNS) characterized by neuroinflammation leading to demyelination. Recently a combination of Δ9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) extracted from
Externí odkaz:
https://doaj.org/article/dc2c251becc34000a7691aaad8b5e491
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Obesity is characterized by chronic low-grade inflammation that contributes to development of cardiometabolic disorders. Cannabinoid receptor 1 (CB1) antagonists attenuate diet-induced obesity (DIO) and related inflammation, although the precise anti
Externí odkaz:
https://doaj.org/article/01521d1db0824bc0bc3dddc10560368b