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Differentiation is inhibited and a senescence pathway is activated when simian virus 40 tsA 58-transformed human retinoblasts are grown at the restrictive temperature

Autor: P H, Gallimore, P S, Lecane, B, Hann, R J, Grand

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(7)

Neonatal human retina cells transformed by the SV40 tumor antigens were shown to leave the cell cycle and differentiate following treatment with agents that raise intracellular levels of cyclic AMP. This was true for both precrisis and immortal cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::210a2e0c625441be5b224ea41be55689
https://pubmed.ncbi.nlm.nih.gov/9218870

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