Zobrazeno 1 - 10
of 21
pro vyhledávání: '"P S, Gulko"'
Autor:
Alberto Verlato, Teresina Laragione, Sofia Bin, Randie H. Kim, Fadi Salem, Percio S. Gulko, Paolo Cravedi
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Systemic Lupus Erythematosus (SLE) has a strong genetic susceptibility, but little is known about the impact of diet on disease severity. The Western diet is typically deficient in magnesium (Mg), and given the immunomodulatory ef
Externí odkaz:
https://doaj.org/article/230046683bbb446292793d2d2e07ba73
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Rheumatoid arthritis (RA) is a common autoimmune and inflammatory disease characterized by inflammation and hyperplasia of the synovial tissues. RA pathogenesis involves multiple cell types, genes, transcription factors (TFs) and networks. Yet, littl
Externí odkaz:
https://doaj.org/article/429edf280d684d168175af9d2ccd6b43
Autor:
Alberto Verlato, Teresina Laragione, Sofia Bin, Randie H. Kim, Fadi Salem, Percio S. Gulko, Paolo Cravedi
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9d7debb8675945758fafbae9f17035a9
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110158- (2024)
Summary: Receptor tyrosine kinases (RTKs) have an important role in arthritis severity and in models of rheumatoid arthritis (RA), but their regulation is not fully understood. The dual specificity phosphatase 6 (DUSP6) has been implicated in the reg
Externí odkaz:
https://doaj.org/article/94f3562ae391453988d081cb784d381c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHuntingtin-interacting protein-1 (HIP1) is a new arthritis severity gene implicated in the regulation of the invasive properties of rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). These invasive properties of FLS strongly corr
Externí odkaz:
https://doaj.org/article/0585561c98fb4c61a407c7688aa2fcb7
Autor:
Alyssa Torres, Sarah Kang, Christopher B. Mahony, Martha Cedeño, Patricia G. Oliveira, Marta Fernandez-Bustamante, Samuel Kemble, Teresina Laragione, Percio S. Gulko, Adam P. Croft, Elsa Sanchez-Lopez, Shigeki Miyamoto, Monica Guma
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundGlucose metabolism, specifically, hexokinase 2 (HK2), has a critical role in rheumatoid arthritis (RA) fibroblast-like synoviocyte (FLS) phenotype. HK2 localizes not only in the cytosol but also in the mitochondria, where it protects mitoch
Externí odkaz:
https://doaj.org/article/56bc636062be4eb9b0e55981ccd93727
Autor:
Teresina Laragione, Carolyn Harris, Nasim Azizgolshani, Christine Beeton, Gerold Bongers, Percio S. Gulko
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104603- (2023)
Summary: Background: Rheumatoid arthritis (RA) is a common autoimmune disease with emerging environmental and microbiome risk factors. The western diet is typically deficient in magnesium (Mg), and there is some evidence suggesting that Mg may have a
Externí odkaz:
https://doaj.org/article/2bc7b2fb9af14aa9bb33509b454232bc
Autor:
Ryan C. Ungaro, Manasi Agrawal, Sarah Park, Robert Hirten, Jean‐Frederic Colombel, Kathryn Twyman, Percio S. Gulko, Eyal Klang
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 2, Pp 111-115 (2021)
Objective There are limited data on the impact of coronavirus disease 2019 (COVID‐19) on hospitalized patients with autoimmune and chronic inflammatory disease (AICID) compared with patients who do not have AICID. We sought to evaluate whether pati
Externí odkaz:
https://doaj.org/article/0c316329291a4300bfe67cb601d5c383
Autor:
Lili Chen, Madhura Deshpande, Marcos Grisotto, Paola Smaldini, Roberto Garcia, Zhengxiang He, Percio S. Gulko, Sergio A. Lira, Glaucia C. Furtado
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Psoriasis (PS) is a chronic skin inflammation. Up to 30% of the patients with PS develop psoriatic arthritis (PsA), a condition characterized by inflammatory arthritis that affects joints or entheses. Although there is mounting evidence for
Externí odkaz:
https://doaj.org/article/d46e0aa1bb81478b9dd088bb5b12120a
Autor:
Mark R. Tanner, Michael W. Pennington, Satendra S. Chauhan, Teresina Laragione, Pércio S. Gulko, Christine Beeton
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-21 (2019)
Abstract Background Fibroblast-like synoviocytes (FLS) and CCR7− effector memory T (TEM) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas TEM cells
Externí odkaz:
https://doaj.org/article/96a71378e38d4196b2cdb3f6084d13a6