Zobrazeno 1 - 10
of 490
pro vyhledávání: '"P Roddie"'
Autor:
Orla McCourt, Paul Maciocia, Claire Roddie, Angela Hwang, Leigh Wood, Aikaterini Panopoulou, Deborah Ann Springell, Maise Al Bakir, Maeve O'Reilly
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1033-1037 (2024)
Abstract Introduction This report outlines the evaluation of physiotherapist‐led prehabilitation/rehabilitation for recipients of chimeric antigen receptor T (CAR‐T) cell therapy. Methods A hybrid approach was used, incorporating in‐person asse
Externí odkaz:
https://doaj.org/article/6bd3cfb7d68a4538b79ef361cacaa10c
Autor:
Macarena Oporto Espuelas, Saskia Burridge, Amy A. Kirkwood, Denise Bonney, Kelly Watts, Geoff Shenton, Katarzyna A. Jalowiec, Maeve A. O’Reilly, Claire Roddie, Anna Castleton, Katherine Clesham, Emma Nicholson, Rajesh Alajangi, Shilpa Prabhu, Lindsay George, Ben Uttenthal, Maria Gabelli, Lorna Neill, Caroline Besley, Sridhar Chaganti, Robert F. Wynn, Jack Bartram, Robert Chiesa, Giovanna Lucchini, Vesna Pavasovic, Anupama Rao, Kanchan Rao, Juliana Silva, Sujith Samarasinghe, Ajay Vora, Peter Clark, Michelle Cummins, David I. Marks, Persis Amrolia, Rachael Hough, Sara Ghorashian
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract CAR T-cell therapy has transformed relapsed/refractory (r/r) B-cell precursor acute lymphoblastic leukaemia (B-ALL) management and outcomes, but following CAR T infusion, interventions are often needed. In a UK multicentre study, we retrospe
Externí odkaz:
https://doaj.org/article/1e1c7d0bb80d4261a46effd3f77c1a63
Autor:
Gloria Iacoboni, Mario A. Sánchez‐Salinas, Kai Rejeski, Ana Á. Martín‐López, Mi Kwon, Víctor Navarro, Katarzyna A. Jalowiec, Rafael Hernani, Juan L. Reguera‐Ortega, Laura Gallur, Viktoria Blumenberg, María Herrero‐García, Claire Roddie, Ana Benzaquén, Javier Delgado‐Serrano, Rebeca Bailén, Cecilia Carpio, Paula Amat, Lucia López‐Corral, Lourdes Martín‐Martín, Mariana Bastos, Marion Subklewe, Maeve O'Reilly, Pere Barba
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Bridging therapy (BT) after leukapheresis is required in most relapsed/refractory (R/R) large B‐cell lymphoma (LBCL) patients receiving chimeric antigen receptor (CAR) T cells. Bendamustine‐containing regimens are a potential BT option.
Externí odkaz:
https://doaj.org/article/cdbf64d4db8243168467791d3772b7b2
Autor:
Maeve A. O'Reilly, William Wilson, David Burns, Andrea Kuhnl, Frances Seymour, Ben Uttenthal, Caroline Besley, Rajesh Alajangi, Thomas Creasey, Shankara Paneesha, Johnathon Elliot, Carlos Gonzalez Arias, Sunil Iyengar, Matthew R. Wilson, Alison Delaney, Lourdes Rubio, Jonathan Lambert, Khalil Begg, Stephen Boyle, Kathleen P. L. Cheok, Graham P. Collins, Claire Roddie, Rod Johnson, Robin Sanderson
Publikováno v:
HemaSphere, Vol 8, Iss 6, Pp n/a-n/a (2024)
Abstract Brexucabtagene autoleucel (brexu‐cel) is an autologous CD19 CAR T‐cell product, approved for relapsed/refractory (r/r) mantle cell lymphoma (MCL). In ZUMA‐2, brexu‐cel demonstrated impressive responses in patients failing ≥2 lines,
Externí odkaz:
https://doaj.org/article/2580c990e3d748ad908ab8da5f93b054
Autor:
Gloria Iacoboni, Josu Iraola‐Truchuelo, Maeve O'Reilly, Víctor Navarro, Tobias Menne, Mi Kwon, Ana África Martín‐López, Sridhar Chaganti, Javier Delgado, Claire Roddie, Ariadna Pérez, Jane Norman, Manuel Guerreiro, Adam Gibb, Ana Carolina Caballero, Caroline Besley, Nuria Martínez‐Cibrián, Alberto Mussetti, Robin Sanderson, Hugo Luzardo, Sunil Iyengar, Jose Maria Sánchez, Ceri Jones, Juan‐Manuel Sancho, Pere Barba, Anne‐Louise Latif, Lucia López‐Corral, Rafael Hernani, Juan Luis Reguera, Anna Sureda, Alejandro Martin Garcia‐Sancho, Mariana Bastos, Pau Abrisqueta, Andrea Kuhnl
Publikováno v:
HemaSphere, Vol 8, Iss 5, Pp n/a-n/a (2024)
Abstract Over 60% of relapsed/refractory (R/R) large B‐cell lymphoma (LBCL) patients who receive chimeric antigen receptor (CAR) T cells will experience disease progression. There is no standard next line of therapy and information in this setting
Externí odkaz:
https://doaj.org/article/da69c64401f4489eb88ab02b2a46bb49
Autor:
Christianne Bourlon, Claire Roddie, Tobias Menne, Jane Norman, Maeve O’Reilly, Adam Gibb, Caroline Besley, Sridhar Chaganti, Carlos Gonzalez Arias, Ceri Jones, Abdalla Dikair, Sharon Allen, Frances Seymour, Wendy Osborne, Amrith Mathew, William Townsend, Piers EM Patten, Eleni Thoulouli, Ahmed Abdulgawad, Sanne Lugthart, Robin Sanderson, Amy A Kirkwood, Andrea Kuhnl
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/b6135250d1674766ba4e7c30eb20df47
Autor:
Maeve A. O'Reilly, Lorna Neill, Simon M. Collin, Neil Stone, Deborah Springell, Jeremy Mensah, Kathleen P. L. Cheok, Katarzyna Jalowiec, Reuben Benjamin, Andrea Kuhnl, Claire Roddie, Robin Sanderson
Publikováno v:
HemaSphere, Vol 8, Iss 1, Pp n/a-n/a (2024)
Abstract Infection has emerged as the chief cause of non‐relapse mortality (NRM) post CD19‐targeting chimeric antigen receptor T‐cell therapy (CAR‐T) therapy. Even though up to 50% of patients may remain infection‐free, many suffer multiple
Externí odkaz:
https://doaj.org/article/b2cae7a4b52d4e08b911dbd4be07370b
Autor:
Rosie Woodruff, Farhaan Parekh, Katarina Lamb, Leila Mekkaoui, Christopher Allen, Katerina Smetanova, Jasmine Huang, Alex Williams, Gerardo Santiago Toledo, Koki Lilova, Claire Roddie, James Sillibourne, Martin Pule
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101123- (2023)
Base editing is a revolutionary gene-editing technique enabling the introduction of point mutations into the genome without generating detrimental DNA double-stranded breaks. Base-editing enzymes are commonly delivered in the form of modified linear
Externí odkaz:
https://doaj.org/article/d64ddca434ba43a18b1b128f94a63b4e
Akademický článek
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Autor:
Harry Dolstra, Claire Roddie, Martin A Pule, Vedika Mehra, Giulia Agliardi, Juliana Dias Alves Pinto, Manar S Shafat, Amaia Cadinanos Garai, Louisa Green, Alastair Hotblack, Fred Arce Vargas, Karl S Peggs, Anniek B van der Waart
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background AUTO1 is a fast off-rate CD19-targeting chimeric antigen receptor (CAR), which has been successfully tested in adult lymphoblastic leukemia. Tscm/Tcm-enriched CAR-T populations confer the best expansion and persistence, but Tscm/Tcm number
Externí odkaz:
https://doaj.org/article/304fa86b5512400a84f30e4d82b38677