Zobrazeno 1 - 10
of 74
pro vyhledávání: '"P Robin Hiesinger"'
Autor:
Friederike E Kohrs, Ilsa-Maria Daumann, Bojana Pavlovic, Eugene Jennifer Jin, F Ridvan Kiral, Shih-Ching Lin, Filip Port, Heike Wolfenberg, Thomas F Mathejczyk, Gerit A Linneweber, Chih-Chiang Chan, Michael Boutros, P Robin Hiesinger
Publikováno v:
eLife, Vol 10 (2021)
Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function. Here, we report the generation and characterization of m
Externí odkaz:
https://doaj.org/article/1d73470d06fd4145826f1e3724bfe42d
Publikováno v:
eLife, Vol 4 (2015)
Filopodial dynamics are thought to control growth cone guidance, but the types and roles of growth cone dynamics underlying neural circuit assembly in a living brain are largely unknown. To address this issue, we have developed long-term, continuous,
Externí odkaz:
https://doaj.org/article/61b7ce161cff4e4a97a99c9babfc2c37
Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling
Autor:
Marlen Zschätzsch, Carlos Oliva, Marion Langen, Natalie De Geest, Mehmet Neset Özel, W Ryan Williamson, William C Lemon, Alessia Soldano, Sebastian Munck, P Robin Hiesinger, Natalia Sanchez-Soriano, Bassem A Hassan
Publikováno v:
eLife, Vol 3 (2014)
Axonal branching allows a neuron to connect to several targets, increasing neuronal circuit complexity. While axonal branching is well described, the mechanisms that control it remain largely unknown. We find that in the Drosophila CNS branches devel
Externí odkaz:
https://doaj.org/article/a438c93848584e60b9de01501cf0ad54
Autor:
Smita Cherry, Eugene Jennifer Jin, Mehmet Neset Özel, Zhiyuan Lu, Egemen Agi, Dong Wang, Wei-Hung Jung, Daniel Epstein, Ian A Meinertzhagen, Chih-Chiang Chan, P Robin Hiesinger
Publikováno v:
eLife, Vol 2 (2013)
The small GTPase Rab7 is a key regulator of endosomal maturation in eukaryotic cells. Mutations in rab7 are thought to cause the dominant neuropathy Charcot-Marie-Tooth 2B (CMT2B) by a gain-of-function mechanism. Here we show that loss of rab7, but n
Externí odkaz:
https://doaj.org/article/768194f82ab142ea8d1eef5d042a5971
Autor:
Eugene Jennifer Jin, Chih-Chiang Chan, Egemen Agi, Smita Cherry, Elizabeth Hanacik, Michael Buszczak, P Robin Hiesinger
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40912 (2012)
We recently generated rab-Gal4 lines for 25 of 29 predicted Drosophila rab GTPases. These lines provide tools for the expression of reporters, mutant rab variants or other genes, under control of the regulatory elements of individual rab loci. Here,
Externí odkaz:
https://doaj.org/article/7b82d64dc4db4095883c8db6522828ec
Publikováno v:
PLoS Biology, Vol 8, Iss 12, p e1000553 (2010)
Axon pathfinding and synapse formation rely on precise spatiotemporal localization of guidance receptors. However, little is known about the neuron-specific intracellular trafficking mechanisms that underlie the sorting and activity of these receptor
Externí odkaz:
https://doaj.org/article/d8f2b50a7b184cd988b84dd7fc024f16
Autor:
R Grace Zhai, Yu Cao, P Robin Hiesinger, Yi Zhou, Sunil Q Mehta, Karen L Schulze, Patrik Verstreken, Hugo J Bellen
Publikováno v:
PLoS Biology, Vol 4, Iss 12, p e416 (2006)
Wallerian degeneration refers to a loss of the distal part of an axon after nerve injury. Wallerian degeneration slow (Wld(s)) mice overexpress a chimeric protein containing the NAD synthase NMNAT (nicotinamide mononucleotide adenylyltransferase 1) a
Externí odkaz:
https://doaj.org/article/c1754f73d8cc4639b20653bc4a1362ba
Publikováno v:
PLoS Biology, Vol 4, Iss 3, p e63 (2006)
Acetylcholine is the major excitatory neurotransmitter in the central nervous system of insects. Mutant analysis of the Dalpha7 nicotinic acetylcholine receptor (nAChR) of Drosophila shows that it is required for the giant fiber-mediated escape behav
Externí odkaz:
https://doaj.org/article/dc97c03a800a47be879279721e197395
Autor:
Bassem A. Hassan, P. Robin Hiesinger
Publikováno v:
Autophagy. :1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49e093b6f4efafe51b8372ccaea7c1d
https://doi.org/10.1080/15548627.2023.2179778
https://doi.org/10.1080/15548627.2023.2179778
