Zobrazeno 1 - 10
of 27
pro vyhledávání: '"P R Lichter"'
Autor:
Janey L Wiggs, Brian L Yaspan, Michael A Hauser, Jae H Kang, R Rand Allingham, Lana M Olson, Wael Abdrabou, Bao J Fan, Dan Y Wang, Wendy Brodeur, Donald L Budenz, Joseph Caprioli, Andrew Crenshaw, Kristy Crooks, Elizabeth Delbono, Kimberly F Doheny, David S Friedman, Douglas Gaasterland, Terry Gaasterland, Cathy Laurie, Richard K Lee, Paul R Lichter, Stephanie Loomis, Yutao Liu, Felipe A Medeiros, Cathy McCarty, Daniel Mirel, Sayoko E Moroi, David C Musch, Anthony Realini, Frank W Rozsa, Joel S Schuman, Kathleen Scott, Kuldev Singh, Joshua D Stein, Edward H Trager, Paul Vanveldhuisen, Douglas Vollrath, Gadi Wollstein, Sachiko Yoneyama, Kang Zhang, Robert N Weinreb, Jason Ernst, Manolis Kellis, Tomohiro Masuda, Don Zack, Julia E Richards, Margaret Pericak-Vance, Louis R Pasquale, Jonathan L Haines
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002654 (2012)
Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide. Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk alleles for glaucoma-related optic nerve disease. We have performed a meta
Externí odkaz:
https://doaj.org/article/c0f601961fb1441ea4c7117937edd651
Autor:
Yutao Liu, Jason Gibson, Joshua Wheeler, Lydia Coulter Kwee, Cecile M Santiago-Turla, Stephen K Akafo, Paul R Lichter, Douglas E Gaasterland, Sayoko E Moroi, Pratap Challa, Leon W Herndon, Christopher A Girkin, Donald L Budenz, Julia E Richards, R Rand Allingham, Michael A Hauser
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27134 (2011)
DNA copy number variants (CNVs) have been reported in many human diseases including autism and schizophrenia. Primary Open Angle Glaucoma (POAG) is a complex adult-onset disorder characterized by progressive optic neuropathy and vision loss. Previous
Externí odkaz:
https://doaj.org/article/132b754901af4ad7bab0456d12f55515
Publikováno v:
Ophthalmology. 108(5)
The Collaborative Initial Glaucoma Treatment Study (CIGTS) was designed to determine whether patients with newly diagnosed open-angle glaucoma are better treated initially by medicine or immediate filtering surgery. This paper describes the quality-o
Publikováno v:
Journal of pediatric orthopedics. 19(5)
To help determine whether there is a genetic basis to the substantial variability observed in nail-patella syndrome (NPS), we devised a scoring system that quantifies the severity of the orthopaedic characteristics in NPS. Use of this system to score
Publikováno v:
Molecular vision. 5
To examine possible effects of the E323K mutation in the trabecular meshwork glucocorticoid response (TIGR) gene (also known as myocilin [MYOC]), using assays of translocational processing through the endoplasmic reticulum (ER). The E323K mutation wa
Autor:
F W, Rozsa, S, Shimizu, P R, Lichter, A T, Johnson, M I, Othman, K, Scott, C A, Downs, T D, Nguyen, J, Polansky, J E, Richards
Publikováno v:
Molecular vision. 4
The aim of this study was to screen affected members of glaucoma families for mutations in the Trabecular Meshwork Inducible Glucocorticoid Response (TIGR) gene also known by the name myocilin (MYOC) or by combined names such as TIGR/MYOC. Our primar
Autor:
R K Stevens, T J Bergstrom, G L Skuta, K O Karp, P R Lichter, David C. Musch, Eve J. Higginbotham
Publikováno v:
Ophthalmology. 103(4)
Purpose: To determine whether filtering blebs resulting from adjunctive use of mitomycin C (MMC) leads to an increased risk of endophthalmitis. Methods: The authors retrospectively reviewed the records of 232 consecutive trabeculectomies performed at
Autor:
G J, Katz, E J, Higginbotham, P R, Lichter, G L, Skuta, D C, Musch, T J, Bergstrom, A T, Johnson
Publikováno v:
Ophthalmology. 102(9)
To compare the outcome of filtering surgery in high-risk patients using intraoperative mitomycin C (MMC) versus postoperative 5-fluorouracil (5-FU).In a randomized clinical trial, the use of postoperative subconjunctival injections of 5-FU in 19 eyes
Autor:
P R, Lichter
Publikováno v:
American journal of ophthalmology. 117(6)
Major advances in the medical and surgical treatment of glaucoma have occurred since the first Edward Jackson Memorial lecture was delivered 50 years ago. Collaborative clinical trials under the sponsorship of the National Eye Institute are adding to
Publikováno v:
American journal of human genetics. 54(1)
A large Caucasian family is presented, in which a juvenile-onset form of open-angle glaucoma is transmitted in an autosomal dominant fashion. Sixteen affected family members were identified from 31 at-risk individuals descended from the affected foun