Zobrazeno 1 - 10
of 186
pro vyhledávání: '"P R Hawley"'
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal (2024)
The use of anabolic androgenic steroids (AAS), such as testosterone, is associated with a myriad of physiological and behavioral health concerns. Most notably, in both humans and rats, exposure to supraphysiological levels of testosterone has been sh
Externí odkaz:
https://doaj.org/article/bdb6183b0ea24f47bc88068aab59e478
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Dysregulation of nucleocytoplasmic shuttling of histone deacetylase 4 (HDAC4) is associated with several neurodevelopmental and neurodegenerative disorders. Consequently, understanding the roles of nuclear and cytoplasmic HDAC4 al
Externí odkaz:
https://doaj.org/article/d76c16a861864241b5f042adf8f0c479
Publikováno v:
Radiology Case Reports, Vol 18, Iss 5, Pp 1748-1753 (2023)
Intravascular papillary endothelial hyperplasia (Masson's Tumor) is a rare benign endothelial vascular lesion that can mimic angiosarcoma if not properly recognized. It represents less than 2% of all vascular tumors, but has been seen in the postradi
Externí odkaz:
https://doaj.org/article/7e0f19d0ea7e485cafd236faf312a208
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106991- (2023)
Summary: Reproductive strategies are defined by expenditures of time and energy devoted to mating effort, which increases mating opportunities, and parenting effort, which enhances the survival of offspring. We examine tradeoffs between mating effort
Externí odkaz:
https://doaj.org/article/dc785f42e05a40d8a14f40110f7c40d5
Autor:
Angelia J. Hura, Hannah R. Hawley, Wei Jun Tan, Rebecca J. Penny, Jessie C. Jacobsen, Helen L. Fitzsimons
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Coenzyme Q8A encodes the homologue of yeast coq8, an ATPase that is required for the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain. Mutations in COQ8A in humans result in CoQ10 deficiency, the clinical
Externí odkaz:
https://doaj.org/article/4593e29da26d4d7d9fbaf6a6dba5d90e
Publikováno v:
Diagnostics, Vol 13, Iss 12, p 2041 (2023)
Attempts to use computers to aid in the detection of breast malignancies date back more than 20 years. Despite significant interest and investment, this has historically led to minimal or no significant improvement in performance and outcomes with tr
Externí odkaz:
https://doaj.org/article/bf1be22833dc477f88f8810c651dee9e
Publikováno v:
The Cryosphere, Vol 14, Pp 1555-1577 (2020)
Few surface energy balance models for debris-covered glaciers account for the presence of moisture in the debris, which invariably affects the debris layer's thermal properties and, in turn, the surface energy balance and sub-debris melt of a debris-
Externí odkaz:
https://doaj.org/article/c97f854ffc004f52a7cd0e32481abc29
Autor:
Stanley Zhou, James R. Hawley, Fraser Soares, Giacomo Grillo, Mona Teng, Seyed Ali Madani Tonekaboni, Junjie Tony Hua, Ken J. Kron, Parisa Mazrooei, Musaddeque Ahmed, Christopher Arlidge, Hwa Young Yun, Julie Livingstone, Vincent Huang, Takafumi N. Yamaguchi, Shadrielle M. G. Espiritu, Yanyun Zhu, Tesa M. Severson, Alex Murison, Sarina Cameron, Wilbert Zwart, Theodorus van der Kwast, Trevor J. Pugh, Michael Fraser, Paul C. Boutros, Robert G. Bristow, Housheng Hansen He, Mathieu Lupien
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
FOXA1 pioneer transcription factor is recurrently mutated in primary and metastatic prostate tumors. Here, authors identify a set of six cis-regulatory elements in the FOXA1 regulatory plexus harboring somatic SNVs in primary prostate tumors and char
Externí odkaz:
https://doaj.org/article/ced842dd69954226b920c3219e59c1a5
Autor:
Ania Wilczynska, Sarah L. Gillen, Tobias Schmidt, Hedda A. Meijer, Rebekah Jukes-Jones, Claudia Langlais, Kari Kopra, Wei-Ting Lu, Jack D. Godfrey, Benjamin R. Hawley, Kelly Hodge, Sara Zanivan, Kelvin Cain, John Le Quesne, Martin Bushell
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-21 (2019)
Abstract Background Regulation of the mRNA life cycle is central to gene expression control and determination of cell fate. miRNAs represent a critical mRNA regulatory mechanism, but despite decades of research, their mode of action is still not full
Externí odkaz:
https://doaj.org/article/7d0c484dc2a4472ab9ac49baaa014cd9
Autor:
G. Lewis, E. Osterberg, R. Hawley, H. P. Marshall, T. Meehan, K. Graeter, F. McCarthy, T. Overly, Z. Thundercloud, D. Ferris
Publikováno v:
The Cryosphere, Vol 13, Pp 2797-2815 (2019)
The mass balance of the Greenland Ice Sheet (GrIS) in a warming climate is of critical interest in the context of future sea level rise. Increased melting in the GrIS percolation zone due to atmospheric warming over the past several decades has led t
Externí odkaz:
https://doaj.org/article/6c89306fc6614e258ca235ed17eb9ab1