Zobrazeno 1 - 7
of 7
pro vyhledávání: '"P R Findell"'
Autor:
A, Leask, D J, Abraham, D R, Finlay, A, Holmes, D, Pennington, X, Shi-Wen, Y, Chen, K, Venstrom, X, Dou, M, Ponticos, C, Black, C, Bernabeu, J K, Jackman, P R, Findell, M K, Connolly
Publikováno v:
Arthritis & Rheumatism. 46:1857-1865
Objective As an initial approach to understanding the basis of the systemic sclerosis (SSc; scleroderma) phenotype, we sought to identify genes in the transforming growth factor β (TGFβ) signaling pathway that are up-regulated in lesional SSc fibro
Publikováno v:
The Journal of biological chemistry. 269(34)
Numerous recent studies have implicated the src homology 2 and 3 domain-containing protein, Grb2, in coupling protein tyrosine kinase signaling pathways with the Ras signaling pathway. Ligation of the T cell antigen receptor results in the activation
Publikováno v:
Endocrinology. 132(2)
Binding sites labeled by the beta-adrenergic receptor radioligand (-)-[125I]iodocyanopindolol ([125I]ICYP) and the selective D1-subtype dopamine (DA) receptor radioligand (+)-[125I]SCH 23982 were identified on immortalized hypothalamic GnRH neurons (
Publikováno v:
Journal of medicinal chemistry. 32(5)
A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine showed biphasic activity in competition binding stud
Publikováno v:
Progress in clinical and biological research. 92
We have initiated a project designed to isolate and identify the neurohypophysial peptides found in the bovine pineal gland. Our principle interest is to provide definitive molecular evidence in order to eliminate the conflict created by the present
Publikováno v:
Molecular pharmacology. 33(1)
The flexible dopamine (DA) molecule exists in one or the other of its two conformational extremes (alpha- or beta-rotamer) and its receptor in the anterior pituitary gland exists in a high and a low affinity state. A series of novel, rigid DA congene
Publikováno v:
ChemInform. 20
A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine showed biphasic activity in competition binding stud