Zobrazeno 1 - 10
of 34
pro vyhledávání: '"P R, Stanfield"'
Publikováno v:
Brain Research Protocols. 7:68-75
Neurones isolated from various parts of the brain are used extensively for electrophysiological and immuncytochemical studies, as well as to investigate their Ca(2+) homeostasis. In this work we report on an isolation technique that yielded neurones
Autor:
I, Ashmole, D V, Vavoulis, P J, Stansfeld, Puja R, Mehta, J F, Feng, M J, Sutcliffe, P R, Stanfield
Publikováno v:
The Journal of Physiology
Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through
Publikováno v:
The Journal of Physiology. 426:499-520
1. Whole-cell recording was used to investigate the effects of substance P on cultured neurones from the rat nucleus basalis. 2. Brief applications of substance P produced a reduction, about 1 min in duration, of resting membrane conductance. The con
Publikováno v:
The Journal of physiology. 531(Pt 1)
We have studied the effects on ionic selectivity and gating of Kir2.1 of replacing Tyr (Y) in the GYG signature sequence with Phe (Y145F), Leu (Y145L), Met (Y145M), Ala (Y145A) or Val (Y145V). The mutant Y145F showed no changes in ionic selectivity (
Publikováno v:
Neurobiology (Budapest, Hungary). 4(3)
1. We have used patch-clamp methods to study the effects of pH at the cytoplasmic surface of the membrane on ATP-dependent K+ channels (KATP channels) in patches excised from frog (Rana temporaria) skeletal muscle, and to study the kinetics of ATP bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9909bcd93364be1bd67b4109e9a1a1
https://europepmc.org/articles/PMC1179997/
https://europepmc.org/articles/PMC1179997/
Publikováno v:
Advances in experimental medicine and biology. 295
Autor:
P. R. Stanfield
Publikováno v:
Nature. 359:441-441
Autor:
N B Standen, P R Stanfield
Publikováno v:
The Journal of Physiology. 304:415-435
1. A three-electrode voltage clamp method was used to investigate the Rb block of inward rectification in frog sartorius muscle fibres. 2. In a solution containing 80 mM-K+, the potassium conductance increased with increasing hyperpolarization to 3.1
Publikováno v:
Nature. 315:498-501
Much interest has recently centred on the properties of peptides that modulate the excitability of nerve cells. Such compounds include the undecapeptide substance P, which is particularly well established as an excitatory neurotransmitter, and we exa