Zobrazeno 1 - 10
of 97
pro vyhledávání: '"P R, Shepherd"'
Autor:
Christopher Puli'uvea, Tracey Immanuel, Taryn N. Green, Peter Tsai, Peter R. Shepherd, Maggie L. Kalev-Zylinska
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objectives: This study aimed to compile bioinformatic and experimental information for JAK2 missense variants previously reported in myeloproliferative neoplasms (MPN) and determine if germline JAK2-I724T, recently found to be common in New Zealand P
Externí odkaz:
https://doaj.org/article/ce5b4c33076141b4ba8b6008985068fb
Publikováno v:
Conservation, Vol 4, Iss 1, Pp 51-64 (2024)
Zoo collection management is increasingly driven by meeting global conservation needs. Many avian species have experienced population declines throughout Southeast Asia, underscoring the importance of ex situ conservation in these countries. We focus
Externí odkaz:
https://doaj.org/article/fb1c5e84cce847b0a3f0f43348a0d6f7
Autor:
Yuewei Xu, Sarah Spear, Yurui Ma, Marc P. Lorentzen, Michael Gruet, Flora McKinney, Yitao Xu, Chiharu Wickremesinghe, Madelen R. Shepherd, Iain McNeish, Hector C. Keun, Anke Nijhuis
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113307- (2023)
Summary: Ovarian high-grade serous carcinoma (HGSC) is the most common subtype of ovarian cancer with limited therapeutic options and a poor prognosis. In recent years, poly-ADP ribose polymerase (PARP) inhibitors have demonstrated significant clinic
Externí odkaz:
https://doaj.org/article/f92b72689e9e4fa5ac20d9abaf4deae7
Autor:
Michèle Hamers, Angie Elwin, Rosemary-Claire Collard, Chris R. Shepherd, Emma Coulthard, John Norrey, David Megson, Neil D'Cruze
Publikováno v:
FACETS, Vol 8, Iss , Pp 1-18 (2023)
In Canada, there have been calls for increased research into and surveillance of wildlife trade and associated zoonotic disease risks. We provide the first comprehensive analysis of Canadian live wildlife imports over a 7-year period (2014–2020), b
Externí odkaz:
https://doaj.org/article/f2c135c5e7064e67b21fcd85a172bc47
Autor:
Vincent Nijman, K. A. I. Nekaris, Chris R. Shepherd, Lucy Vigne, Ahmad Ardiansyah, Muhammad Ali Imron, Qinyong Ni, Katherine Hedger, Marco Campera, Thais Q. Morcatty
Publikováno v:
Microbiology Research, Vol 14, Iss 1, Pp 116-131 (2023)
Vector-borne diseases spread from wild animals and their associated ectoparasites to humans and domesticated animals. Wildlife markets are recognized as important areas where this transfer can take place. We assessed the potential for spreading vecto
Externí odkaz:
https://doaj.org/article/829a610d38d2428c9e11c2ab405ce501
Autor:
Molly F. Parsons, Matthew F. Allan, Shanshan Li, Tyson R. Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M. Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Hybrid nucleic acid origami has potential for biomedical delivery of mRNA and fabrication of artificial ribozymes. Here, the authors use chemical footprinting and cryo-electron microscopy to reveal insights into nucleic acid origami used to fold mess
Externí odkaz:
https://doaj.org/article/108ab9faee2848f09c545c0415482066
Autor:
Freya R. Shepherd, Kate Davies, Kelly L. Miners, Sian Llewellyn-Lacey, Simon Kollnberger, James E. Redman, Melissa M. Grant, Kristin Ladell, David A. Price, James E. McLaren
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
In peripheral blood mononuclear cells from healthy human donors, the superantigens SpeC and TSST-1 are shown to specifically activate TRBV12-3/12-4+ memory T cells.
Externí odkaz:
https://doaj.org/article/2db234c82e7d48d5a9eec72de7ff370e
Publikováno v:
Nature Conservation, Vol 46, Iss , Pp 41-48 (2022)
The elusive and Critically Endangered silvery pigeon Columba argentina is only found on small offshore islands in western Indonesia and Malaysia. Historically, trade records have suggested that, in addition to habitat degradation and invasive predato
Externí odkaz:
https://doaj.org/article/fd6e123d78a4428d886e569b4985aba1
Autor:
Vincent Nijman, Ahmad Ardiansyah, Abdullah Langgeng, Rifqi Hendrik, Katherine Hedger, Grace Foreman, Thais Q. Morcatty, Penthai Siriwat, S. (Bas) van Balen, James A. Eaton, Chris R. Shepherd, Lalita Gomez, Muhammad Ali Imron, K. A. I. Nekaris
Publikováno v:
Birds, Vol 3, Iss 1, Pp 99-116 (2022)
Monitoring illegal wildlife trade and how the modus operandi of traders changes over time is of vital importance to mitigate the negative effects this trade can have on wild populations. We focused on the trade of birds of prey in Indonesia (2016–2
Externí odkaz:
https://doaj.org/article/adc9edf2329f46c08c5daceb0ef9347b
Autor:
Stewart W. C. Masson, Waruni C. Dissanayake, Sophie C. Broome, Christopher P. Hedges, Wouter M. Peeters, Martin Gram, David S. Rowlands, Peter R. Shepherd, Troy L. Merry
Publikováno v:
Physiological Reports, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract A central characteristic of insulin resistance is the impaired ability for insulin to stimulate glucose uptake into skeletal muscle. While insulin resistance can occur distal to the canonical insulin receptor‐PI3k‐Akt signaling pathway,
Externí odkaz:
https://doaj.org/article/0f3992d53ffb40488d95e17febf0a71a