Zobrazeno 1 - 10
of 16
pro vyhledávání: '"P R, Puopolo"'
Autor:
James G. Flood, P R Puopolo, Judith C. Kando, Ross J. Baldessarini, Franca Centorrino, Sheila A. Volpicelli, Frances R. Frankenburg
Publikováno v:
Clinical Chemistry. 39:1656-1659
We report a new assay to measure the serum concentrations of the atypical antipsychotic drug clozapine and two major metabolites, norclozapine and clozapine-N-oxide. The analytes and an internal standard (triprolidine) were extracted from alkalinized
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 32:798-804
Objective To assess the developmental effects of desipramine (DMI) treatment on the electrocardiogram (ECG), we investigated serum concentrations of DMI ([DMI]), and its major active metabolite 2-hydroxy-desipramine ([OHDMI]) and ECG parameters. Meth
Publikováno v:
Clinical Chemistry. 38:1838-1842
We report the performance of a liquid chromatography (LC) assay for detection and confirmation of cocaine and cocaethylene in serum. A photodiode array (PDA) detector monitors the cyano column effluent at 230 nm for analyte detection. Confirmation of
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 31:691-698
Steady-state serum concentrations of desipramine (DMI) and its metabolite, 2-hydroxydesipramine (OHDMI), were measured in 40 children, 36 adolescents, and 27 adult psychiatric patients. The authors predicted that younger patients would show more effi
Autor:
James G. Flood, R. G. Gonzalez, Perry F. Renshaw, Maurizio Fava, Jerrold F. Rosenbaum, P R Puopolo, Kathy Clancy, Pearlman Jd, Alexander R. Guimaraes
Publikováno v:
American Journal of Psychiatry. 149:1592-1594
In vivo l9fluorine nuclear magnetic resonance spectroscopy was used to measure the brain concentration offluoxetine and norfluoxetine in five patients with obsessive-compulsive disorder and three with major depression. The mean brain:plasma ratio of
Publikováno v:
Clinical chemistry. 41(6 Pt 1)
Autor:
S A, Volpicelli, F, Centorrino, P R, Puopolo, J, Kando, F R, Frankenburg, R J, Baldessarini, J G, Flood
Publikováno v:
Clinical chemistry. 39(8)
We report a new assay to measure the serum concentrations of the atypical antipsychotic drug clozapine and two major metabolites, norclozapine and clozapine-N-oxide. The analytes and an internal standard (triprolidine) were extracted from alkalinized
Autor:
Joseph Biederman, James G. Flood, Ross J. Baldessarini, Timothy E. Wilens, McDermott Sp, P R Puopolo
Publikováno v:
Archives of general psychiatry. 49(9)
To the Editor.— We read with interest the article by Nelson et al 1 on the treatment of depression with fluoxetine and desipramine, particularly regarding effects of fluoxetine on serum levels of desipramine and its major active metabolite, 2-hydro
Publikováno v:
Clinical chemistry. 38(9)
We report the performance of a liquid chromatography (LC) assay for detection and confirmation of cocaine and cocaethylene in serum. A photodiode array (PDA) detector monitors the cyano column effluent at 230 nm for analyte detection. Confirmation of
Publikováno v:
Clinical chemistry. 37(12)
We investigated the applicability of liquid chromatography with photodiode array detection as a serum drug screening technique in an emergency toxicology setting. Basic compounds are extracted from alkalinized serum with hexane and chromatographed on