Zobrazeno 1 - 9
of 9
pro vyhledávání: '"P R, Huggard"'
Publikováno v:
British Journal of Cancer
Chemokine (C-C motif) ligand-2 (CCL2) is a chemoattractant and activator of macrophages and is a key determinant of the macrophage infiltrate into tumours. We demonstrate here that CCL2 is expressed in normal human ovarian surface epithelium (HOSE) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec3da1d2c26354f80d1f1671903f60b
https://doi.org/10.1038/sj.bjc.6602596
https://doi.org/10.1038/sj.bjc.6602596
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 21:207-210
1. The associations between left ventricular hypertrophy (LVH) and specific alleles of the renin and angiotensin-converting enzyme (ACE) genes were studied in patients with essential hypertension and normal blood pressure. 2. LVH was present in 42% o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf22e65565b94b1ee29cf90989a65b7
https://doi.org/10.1111/j.1440-1681.1994.tb02497.x
https://doi.org/10.1111/j.1440-1681.1994.tb02497.x
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 20:320-323
1. Animal studies have implicated the angiotensin-converting enzyme (ACE) gene as an inherited risk factor contributing towards elevation of blood pressure. 2. A polymorphism of the ACE gene, involving the presence or absence of a 287 base pair (bp)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147047e5cdcf51475004a5cbd14f77f6
https://doi.org/10.1111/j.1440-1681.1993.tb01694.x
https://doi.org/10.1111/j.1440-1681.1993.tb01694.x
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 19:315-318
1. Family and population studies have reported that blood pressure has a heritability of 30-50%, but simple genetic models do not readily explain the patterns of inheritance of hypertension. 2. Restriction fragment length polymorphisms were used to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b8613619e759aada33afa92f04dd7c
https://doi.org/10.1111/j.1440-1681.1992.tb00461.x
https://doi.org/10.1111/j.1440-1681.1992.tb00461.x
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(6)
In familial hyperaldosteronism type I (FH-I), inheritance of a hybrid 11beta-hydroxylase/aldosterone synthase gene causes ACTH-regulated aldosterone overproduction. In an attempt to understand the marked variability in hypertension severity in FH-I,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40e3e933769a8d2d2ce1aa7e2d3062d0
https://pubmed.ncbi.nlm.nih.gov/10852445
https://pubmed.ncbi.nlm.nih.gov/10852445
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(11)
We examined in detail biochemical characteristics of 10 normotensive individuals (6 females; age range, 11-43 yr) with glucocorticoid-suppressible hyperaldosteronism (familial hyperaldosteronism type I) in an attempt to understand the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94961df80cded9386b9f893f38eacda5
https://pubmed.ncbi.nlm.nih.gov/10566645
https://pubmed.ncbi.nlm.nih.gov/10566645
Autor:
D J, Torpy, R D, Gordon, J P, Lin, P R, Huggard, S E, Taymans, M, Stowasser, G P, Chrousos, C A, Stratakis
Publikováno v:
The Journal of clinical endocrinology and metabolism. 83(9)
Familial hyperaldosteronism type II (FH-II) is characterized by autosomal dominant inheritance and hypersecretion of aldosterone due to adrenocortical hyperplasia or an aldosterone-producing adenoma; unlike FH type I (FH-I), hyperaldosteronism in FH-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddb1783d6530563d1787fc48b01d8c62
https://pubmed.ncbi.nlm.nih.gov/9745430
https://pubmed.ncbi.nlm.nih.gov/9745430
Publikováno v:
Clinical and experimental pharmacologyphysiology. 24(6)
1. Essential hypertension is characterized by increased vascular resistance due to narrowing of the small arterioles. This may be influenced by vasoactive substances, cell growth and vascular remodelling. 2. A sample of Australian hypertensive and no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdf8783386b20e2d727c37bf60b34a0
https://pubmed.ncbi.nlm.nih.gov/9171958
https://pubmed.ncbi.nlm.nih.gov/9171958
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:600-601
1. Two deficiency alleles of alpha 1-antitrypsin (AAT) called S and Z have been previously associated with lower blood pressure levels. 2. A sample of Australian hypertensive and normotensive subjects was investigated with respect to these alleles. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9b132784b48206e138e34912c9ce77
https://doi.org/10.1111/j.1440-1681.1996.tb02792.x
https://doi.org/10.1111/j.1440-1681.1996.tb02792.x