Zobrazeno 1 - 10 of 17 pro vyhledávání: '"P R, Clapham"'
1
Akademický článek
MENTOR study: Matching expectations and needs to optimize relationships in cardiovascular fellowship training
Autor: Natalija Odanovic, Katharine R. Clapham, Burcu Gul, Celina M. Yong, Judith L. Meadows, S. Elissa Altin
Publikováno v: American Heart Journal Plus, Vol 4, Iss , Pp 100019- (2021)
Study objective: Mentorship is a key component of successful cardiology training. This study sought to understand the alignment of mentorship priorities for fellow-in-training (FIT) mentees and faculty mentors. Design: Cross-sectional survey study. S
Externí odkaz: https://doaj.org/article/667fb36b864449a9aad99c445ac6f5a3
Zobrazit plný text záznamu
2
Akademický článek
Reduced RVSWI Is Associated With Increased Mortality in Connective Tissue Disease Associated Pulmonary Arterial Hypertension
Autor: Katharine R. Clapham, Kristin B. Highland, Youlan Rao, Wassim H. Fares
Publikováno v: Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Rationale: The prognosis of pulmonary arterial hypertension is poor, especially amongst patients with connective tissue disease related pulmonary arterial hypertension. Right ventricular contractility is known to be decreased in scleroderma related p
Externí odkaz: https://doaj.org/article/f448d275dbe84759872999d0c6948a2c
Zobrazit plný text záznamu
3
Akademický článek
MEF2 and the Right Ventricle: From Development to Disease
Autor: Katharine R. Clapham, Inderjit Singh, Isabella S. Capuano, Sudarshan Rajagopal, Hyung J. Chun
Publikováno v: Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Pulmonary arterial hypertension is a progressive and ultimately life-limiting disease in which survival is closely linked to right ventricular function. The right ventricle remains relatively understudied, as it is known to have key developmental and
Externí odkaz: https://doaj.org/article/07783e0c57314d2cb778d18abddf1e6a
Zobrazit plný text záznamu
4
Akademický článek
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.
Autor: David Beauparlant, Peter Rusert, Carsten Magnus, Claus Kadelka, Jacqueline Weber, Therese Uhr, Osvaldo Zagordi, Corinna Oberle, Maria J Duenas-Decamp, Paul R Clapham, Karin J Metzner, Huldrych F Günthard, Alexandra Trkola
Publikováno v: PLoS Pathogens, Vol 13, Iss 3, p e1006255 (2017)
A hallmark of HIV-1 infection is the continuously declining number of the virus' predominant target cells, activated CD4+ T cells. With diminishing CD4+ T cell levels, the capacity to utilize alternate cell types and receptors, including cells that e
Externí odkaz: https://doaj.org/article/070d0eed8e9f43eaa673e40f269e366c
Zobrazit plný text záznamu
5
Akademický článek
Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations.
Autor: Maria Duenas-Decamp, Li Jiang, Daniel Bolon, Paul R Clapham
Publikováno v: PLoS Pathogens, Vol 12, Iss 11, p e1005988 (2016)
The conformation of HIV-1 envelope (Env) glycoprotein trimers is key in ensuring protection against waves of neutralizing antibodies generated during infection, while maintaining sufficient exposure of the CD4 binding site (CD4bs) for viral entry. Th
Externí odkaz: https://doaj.org/article/3d3d605a36d5460c9bcbcc027344042d
Zobrazit plný text záznamu
6
Akademický článek
Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophages.
Autor: Ruizhong Shen, Gang Meng, Christina Ochsenbauer, Paul R Clapham, Jayleen Grams, Lea Novak, John C Kappes, Lesley E Smythies, Phillip D Smith
Publikováno v: PLoS Pathogens, Vol 7, Iss 5, p e1002060 (2011)
Tissue macrophages are derived exclusively from blood monocytes, which as monocyte-derived macrophages support HIV-1 replication. However, among human tissue macrophages only intestinal macrophages are non-permissive to HIV-1, suggesting that the uni
Externí odkaz: https://doaj.org/article/985fc87343b64f33b7824c049e030358
Zobrazit plný text záznamu
8
Vesicular stomatitis virus pseudotypes of retroviruses
Autor: P R, Clapham
Publikováno v: Methods in molecular biology (Clifton, N.J.). 8
Pseudotype viruses are phenotypically mixed virions containing the genome or nucleocapsid of one enveloped virus and the surface or envelope (env) glycoproteins of another. This chapter will concentrate on vesicular stomatitis virus (VSV) pseudotypes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45150de6255696fe97b4de839a8f34c1
https://pubmed.ncbi.nlm.nih.gov/21390704
Zobrazit plný text záznamu
10
Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands
Autor: G, Simmons, J D, Reeves, S, Hibbitts, J T, Stine, P W, Gray, A E, Proudfoot, P R, Clapham
Publikováno v: Immunological reviews. 177
Human and simian immunodeficiency viruses (HIV and SIV) require a seven transmembrane chemokine (7TM) receptor in addition to CD4 for efficient entry into cells. CCR5 and CXCR4 act as major co-receptors for non-syncytium-inducing and syncytium-induci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a61114f7c012e0eaa4e60a32a32cc7d
https://pubmed.ncbi.nlm.nih.gov/11138769
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje