Zobrazeno 1 - 10
of 198
pro vyhledávání: '"P P, SERDIUK"'
In this paper we study a new class of pseudo-differential equations on functions of two $p$-adic variables. It is proved that the correspondent Cauchy problem has a unique solution. Some properties of this solution are studied, in particular, the fin
Externí odkaz:
http://arxiv.org/abs/2409.00136
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2
Autor:
Kathi Ging, Lukas Frick, Johannes Schlachetzki, Andrea Armani, Yanping Zhu, Pierre-André Gilormini, Ashutosh Dhingra, Desirée Böck, Ana Marques, Matthew Deen, Xi Chen, Tetiana Serdiuk, Chiara Trevisan, Stefano Sellitto, Claudio Pisano, Christopher K. Glass, Peter Heutink, Jiang-An Yin, David J. Vocadlo, Adriano Aguzzi
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Mutations in GBA1 encoding the lysosomal enzyme β-glucocerebrosidase (GCase) are among the most prevalent genetic susceptibility factors for Parkinson’s disease (PD), with 10–30% of carriers developing the disease. To identify genetic m
Externí odkaz:
https://doaj.org/article/4c0ae1d7d594437b8f6bf9199fd5b7f6
Publikováno v:
Journal of Ophthalmology, Iss 4, Pp 38-45 (2024)
Purpose: To establish prognostic biomarkers of non-prolefarative diabetic retinopathy (NPDR) progression in T2DM on the basis of examination of clinical, ophthalmological and laboratory (carbohydrate and lipid metabolism and coagulation and hemostasi
Externí odkaz:
https://doaj.org/article/78b291ceaea44440a02ecc41d50dacef
Autor:
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre PA Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2024-2042 (2024)
Abstract Extracellularly released molecular inflammasome assemblies -ASC specks- cross-seed Aβ amyloid in Alzheimer’s disease. Here we show that ASC governs the extent of inflammation-induced amyloid A (AA) amyloidosis, a systemic disease caused b
Externí odkaz:
https://doaj.org/article/361701b3ccf5457e8ccf997a37e06f01
Autor:
Aleš Holfeld, Dina Schuster, Fabian Sesterhenn, Alison K Gillingham, Patrick Stalder, Walther Haenseler, Inigo Barrio-Hernandez, Dhiman Ghosh, Jane Vowles, Sally A Cowley, Luise Nagel, Basavraj Khanppnavar, Tetiana Serdiuk, Pedro Beltrao, Volodymyr M Korkhov, Sean Munro, Roland Riek, Natalie de Souza, Paola Picotti
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 651-675 (2024)
Abstract The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of proteins could help understand disease mechan
Externí odkaz:
https://doaj.org/article/111e459619b140979ac5a006ab8a5025
Autor:
Lukas Frey, Dhiman Ghosh, Bilal M Qureshi, David Rhyner, Ricardo Guerrero-Ferreira, Aditya Pokharna, Witek Kwiatkowski, Tetiana Serdiuk, Paola Picotti, Roland Riek, Jason Greenwald
Publikováno v:
eLife, Vol 12 (2024)
The aggregation of the protein α-synuclein is closely associated with several neurodegenerative disorders and as such the structures of the amyloid fibril aggregates have high scientific and medical significance. However, there are dozens of unique
Externí odkaz:
https://doaj.org/article/b3148a9d0d8343938297881e5df6743e
Publikováno v:
Вестник Воронежского государственного университета: Серия экономика и управление, Iss 1, Pp 25-37 (2024)
Subject. Theoretical and practical issues related to customs control carried out by customs control authorities after the release of goods into free circulation. Objectives. Studying the main specific characteristics of the operation and development
Externí odkaz:
https://doaj.org/article/520bca72662c4cfd974f3e3f09a967b3
Publikováno v:
IEEE Access, Vol 12, Pp 123804-123810 (2024)
To generate the maximum amount of electricity, solar panels of a spacecraft must be placed at the position of maximum illumination when the surface normal of the panels is close to the direction of the sun. In micro-and nanosatellites, solar panels a
Externí odkaz:
https://doaj.org/article/ef77c20c49ed4879885c19b4586a95aa
In earlier papers (A. N. Kochubei, Pacif. J. Math., 269 (2014), 355-369; J. Math. Anal. Appl.483 (2020), Article 123609), one of the authors developed a theory of pseudo-differential equations for radial real-valued functions on a non-Archimedean loc
Externí odkaz:
http://arxiv.org/abs/2203.06623
Publikováno v:
Nauka ta progres transportu, Iss 3(103), Pp 5-12 (2023)
Purpose. The study is aimed at: gaining new knowledge about the use of electric motors in robotics; evaluation and selection of motors that are appropriate for use in robots that will move along the railway line and accurately determine the location
Externí odkaz:
https://doaj.org/article/7e990991f5e04068bed7261b27f1a103