Zobrazeno 1 - 9 of 9 pro vyhledávání: '"P O, Ogbunude"'
1
In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga
Autor: P O, Ogbunude, S A, Asiri
Publikováno v: Drugs under experimental and clinical research. 27(4)
Treatment with the drugs berenil, dibromopropamidine, pentamidine and CGP-4O-215 were found to alter levels of intracellular polyamines of Acanthamoeba polyphagia trophozoites in organisms. While the polyamine, spermidine, consistently remained highe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::125a218c5510e06983878d146c9be949
https://pubmed.ncbi.nlm.nih.gov/11822222
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3
De novo purine biosynthesis in a free living protozoan parasite, Acanthamoeba polyphaga [correction of polypha]
Autor: P O, Ogbunude, H P, Baer
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 44(1)
A free living protozoon, Acanthamoeba polyphaga 435/89, was shown to utilize radiolabelled formate and glycine as precursors for purine biosynthesis and to grow in medium devoid of any source of preformed purine compounds. The organism also incorpora
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0f53997038e962c60dc3abf9453485e
https://pubmed.ncbi.nlm.nih.gov/8516627
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4
Experimental chemotherapy of leishmaniasis with adenosine analogue Formycin A, in combination with inhibitor of nucleoside transport, nitrobenzylthioinosinate
Autor: P O, Ogbunude, M H, al-Jaser
Publikováno v: Drugs under experimental and clinical research. 18(10)
A single dose of the adenosine analogue Formycin A (FoA) (20 mg/kg), combined with nitrobenzyl mercaptopurine ribonucleoside 5'-monophosphate (NBMPR-P) (10 mg/kg), a prodrug of nitrobenzylthioinosine (NBMPR), was effective in reducing the size of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37c90e2073e659a5fe36ccdbe3b32ee8
https://pubmed.ncbi.nlm.nih.gov/1306154
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5
New method for detachment and quantitation of Acanthamoeba trophozoites in culture
Autor: P O, Ogbunude, S, Asiri, H P, Baer, D C, Warhurst
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 42(4)
Trophozoites of two Acanthamoeba polyphaga strains (RYD and 435) were readily detached from plastic culture flasks or multiwell plates by 5 min exposure to a detaching fluid containing 0.005% of Triton X-100 and 0.05% ammonium sulphate. This treatmen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e8b12bbd011963a3a35113ce1ba3218
https://pubmed.ncbi.nlm.nih.gov/1796243
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7
Effect of nitrobenzylthioinosinate on the toxicity of tubercidin and ethidium against Trypanosoma gambiense
Autor: P O, Ogbunude, C O, Ikediobi
Publikováno v: Acta tropica. 39(3)
The coadministration of tubercidin and ethidium to mice infected with Trypanosoma gambiense gave a better parasite clearance than either of the single drugs. The combination was also more toxic to the mice but the inclusion of nitrobenzylthioinosinat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f876c2770ed320b937e6ab77558c62a
https://pubmed.ncbi.nlm.nih.gov/6128890
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8
Binding of [G-3H]6-(4-nitrobenzylmercapto)purine ribonucleoside to isolated membranes. Inhibitory effect of mioflazine and its derivatives
Autor: P O, Ogbunude, H P, Baer
Publikováno v: Biochemical pharmacology. 38(18)
The binding of [G-3H]-6-(4-nitrobenzylmercapto)purine ribonucleoside [( G-3H]NBMPR) was investigated using a centrifugation assay with membrane preparations from hamster tissues including liver, lung, kidney and heart. Only liver and lung membranes s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a8c7547e837c7237b431e95485127a7
https://pubmed.ncbi.nlm.nih.gov/2783156
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9
A simple procedure for the isolation of schistosomules for biochemical studies or culture
Autor: P O, Ogbunude, A, Selim, A, Haq, H P, Baer
Publikováno v: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 40(3)
Incubation of cercariae of Schistosoma mansoni in a 1:1 mixture of Eagle's Minimal Essential Medium and rat serum at 42 degrees C for only 5 minutes, plus subsequent vortexing, resulted in at least 98% conversion of cercariae to schistosomules. Subse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6096efdd2e9b0190e486ac7c1e08b0df
https://pubmed.ncbi.nlm.nih.gov/2617043
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