Zobrazeno 1 - 10
of 2 114
pro vyhledávání: '"P Nuutila"'
Autor:
Richard Aarnio, Anna Kirjavainen, Johan Rajander, Sarita Forsback, Kari Kalliokoski, Pirjo Nuutila, Zvonko Milicevic, Tamer Coskun, Axel Haupt, Iina Laitinen, Merja Haaparanta-Solin
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Fatty acid uptake can be measured using PET and 14-(R,S)‐[18F]fluoro‐6‐thia‐heptadecanoic acid ([18F]FTHA). However, the relatively rapid rate of [18F]FTHA metabolism significantly affects kinetic modeling of tissue uptake
Externí odkaz:
https://doaj.org/article/431ec5815c0a4c829a4b8d52c133bc9b
Autor:
Somayah S. Elsayed, Helga U. van der Heul, Xiansha Xiao, Aleksi Nuutila, Laura R. Baars, Changsheng Wu, Mikko Metsä-Ketelä, Gilles P. van Wezel
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Angucyclines are type II polyketide natural products, often characterized by unusual structural rearrangements through B- or C-ring cleavage of their tetracyclic backbone. While the enzymes involved in B-ring cleavage have been extensively s
Externí odkaz:
https://doaj.org/article/552e4cdb804544a5861a5f3671f524ed
Autor:
Tuulia Malén, Severi Santavirta, Sven De Maeyer, Jouni Tuisku, Valtteri Kaasinen, Tuomas Kankare, Janne Isojärvi, Juha Rinne, Jarmo Hietala, Pirjo Nuutila, Lauri Nummenmaa
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103578- (2024)
Purpose: Aberrant dopaminergic function is linked with motor, psychotic, and affective symptoms, but studies have typically compared a single patient group with healthy controls. Methods: Here, we investigated the variation in striatal (caudate nucle
Externí odkaz:
https://doaj.org/article/ceb6e54fbc0e4584bd6ed5365cf87b01
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24104- (2024)
Indoor exposure to microbial growth, caused by moisture damage, has been an established health risk for several decades. It is likely that a damp indoor environment contains biological pollutants that trigger both the innate and adaptive branches of
Externí odkaz:
https://doaj.org/article/76ee40b2540a436db0d96058cde6541f
Autor:
Nicola Morrice, Susanne Vainio, Kirsi Mikkola, Lidy van Aalten, Jennifer R. Gallagher, Michael L.J. Ashford, Alison D. McNeilly, Rory J. McCrimmon, Alexandra Grosfeld, Patricia Serradas, Jukka Koffert, Ewan R. Pearson, Pirjo Nuutila, Calum Sutherland
Publikováno v:
Molecular Metabolism, Vol 77, Iss , Pp 101807- (2023)
Objectives: Metformin is the first line therapy recommended for type 2 diabetes. However, the precise mechanism of action remains unclear and up to a quarter of patients show some degree of intolerance to the drug, with a similar number showing poor
Externí odkaz:
https://doaj.org/article/60ff9417f6b94a40a6a38abc3d1becfc
Akademický článek
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Autor:
Marco Bucci, Eleni Rebelos, Vesa Oikonen, Juha Rinne, Lauri Nummenmaa, Patricia Iozzo, Pirjo Nuutila
Publikováno v:
Metabolites, Vol 14, Iss 2, p 114 (2024)
Accurate positron emission tomography (PET) data quantification relies on high-quality input plasma curves, but venous blood sampling may yield poor-quality data, jeopardizing modeling outcomes. In this study, we aimed to recover sub-optimal input fu
Externí odkaz:
https://doaj.org/article/13657f5d871a4831a50e2afe59b9de1b
Autor:
Mueez U-Din, Vanessa D. de Mello, Marjo Tuomainen, Juho Raiko, Tarja Niemi, Tobias Fromme, Anton Klåvus, Nadine Gautier, Kimmo Haimilahti, Marko Lehtonen, Karsten Kristiansen, John W. Newman, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Ez-Zoubir Amri, Martin Klingenspor, Pirjo Nuutila, Eija Pirinen, Kati Hanhineva, Kirsi A. Virtanen
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113131- (2023)
Summary: Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for mitochondrial function, nicotinamide adenine dinucleotide (NAD+), but limited knowledge
Externí odkaz:
https://doaj.org/article/1c0fa9c527de49b8bd7b766598b67913
Autor:
Eleni Rebelos, Giuseppe Daniele, Beatrice Campi, Alessandro Saba, Kalle Koskensalo, Jukka Ihalainen, Ekaterina Saukko, Pirjo Nuutila, Walter H. Backes, Jacobus F. A. Jansen, Pieter C. Dagnelie, Sebastian Köhler, Bastiaan E. de Galan, Thomas T. van Sloten, Coen D. A. Stehouwer, Ele Ferrannini
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract N-acetylaspartate (NAA) is the second most abundant metabolite in the human brain; although it is assumed to be a proxy for a neuronal marker, its function is not fully elucidated. NAA is also detectable in plasma, but its relation to cerebr
Externí odkaz:
https://doaj.org/article/59708c8af1614fe5aa779d1718cc4318
Akademický článek
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