Zobrazeno 1 - 10
of 37
pro vyhledávání: '"P N Furness"'
Autor:
Adam J. Carlton, Jing-Yi Jeng, Fiorella C. Grandi, Francesca De Faveri, Ana E. Amariutei, Lara De Tomasi, Andrew O’Connor, Stuart L. Johnson, David N. Furness, Steve D.M. Brown, Federico Ceriani, Michael R. Bowl, Mirna Mustapha, Walter Marcotti
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114025- (2024)
Summary: Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming synapses with inner hair cells (IHCs) in the mammalian cochlea. The molecular mechanisms regulating the formation of the post-synaptic
Externí odkaz:
https://doaj.org/article/003f391f46fe499b876a09eda87c4a9d
Autor:
Jacqueline A Tickle, Jon Sen, Christopher Adams, David N Furness, Rupert Price, Viswapathi Kandula, Nikolaos Tzerakis, Divya M Chari
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1057-1061 (2023)
The use of live animal models for testing new therapies for brain and spinal cord repair is a controversial area. Live animal models have associated ethical issues and scientific concerns regarding the predictability of human responses. Alternative m
Externí odkaz:
https://doaj.org/article/fc1c757151c443d69fc5c2e6bdcffe83
Publikováno v:
Ecology and Evolution, Vol 11, Iss 13, Pp 8923-8940 (2021)
Abstract It has often been suggested that the productivity of an ecosystem affects the number of species that it can support. Despite decades of study, the nature, extent, and underlying mechanisms of this relationship are unclear. One suggested mech
Externí odkaz:
https://doaj.org/article/0e1f5b779b934fdaba553a91e18fa6aa
Autor:
Euan N. Furness, Robert W. Furness
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Masting behaviour of Sitka spruce Picea sitchensis may influence Eurasian siskin Spinus spinus breeding ecology as breeding siskins specialize on spruce seeds. We caught siskins and other small passerines over 16 years using mist nets adjace
Externí odkaz:
https://doaj.org/article/71a47bb52b8444658003a3033a387dde
Autor:
Euan N. Furness, Robert A. Robinson
Publikováno v:
Ecology and Evolution, Vol 9, Iss 3, Pp 1202-1210 (2019)
Abstract The optimum body mass of passerine birds typically represents a trade‐off between starvation risk, which promotes fat gain, and predation pressure, which promotes fat loss to maintain maneuvrability. Changes in ecological factors that affe
Externí odkaz:
https://doaj.org/article/46461eab376e4e888c01490ffc81ced6
Autor:
Laura F. Corns, Stuart L. Johnson, Terri Roberts, Kishani M. Ranatunga, Aenea Hendry, Federico Ceriani, Saaid Safieddine, Karen P. Steel, Andy Forge, Christine Petit, David N. Furness, Corné J. Kros, Walter Marcotti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Mechanoelectrical transducer (MET) channels on the tips of inner hair cells are essential for transducing auditory sensory information. Here, the authors show that disrupting MET channel function also prevents the preservation of normal inner hair ce
Externí odkaz:
https://doaj.org/article/ecfdf3bfbfef42019680748d1efaa1ea
Autor:
David N. Furness
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Cochlear fibrocytes are a homeostatic supporting cell type embedded in the vascularized extracellular matrix of the spiral ligament, within the lateral wall. Here, they participate in the connective tissue syncytium that enables potassium recirculati
Externí odkaz:
https://doaj.org/article/852cd456585b4ff4bb1bda3fb144a4a8
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185285 (2017)
Mechanosensory transduction by vertebrate hair cells depends on a protein complex at the tips of shorter stereocilia associated with mechanoelectrical transduction channels activated by tip links in the hair bundle. In mammalian hair cells, this comp
Externí odkaz:
https://doaj.org/article/8943a73677f345cf850fa5d4f3299425
Autor:
Valeria Zampini, Lukas Rüttiger, Stuart L Johnson, Christoph Franz, David N Furness, Jörg Waldhaus, Hao Xiong, Carole M Hackney, Matthew C Holley, Nina Offenhauser, Pier Paolo Di Fiore, Marlies Knipper, Sergio Masetto, Walter Marcotti
Publikováno v:
PLoS Biology, Vol 9, Iss 4, p e1001048 (2011)
Hair cells of the mammalian cochlea are specialized for the dynamic coding of sound stimuli. The transduction of sound waves into electrical signals depends upon mechanosensitive hair bundles that project from the cell's apical surface. Each stereoci
Externí odkaz:
https://doaj.org/article/f1f480656edf4f8baf0c7d15e540c68d
Autor:
Kumar N Alagramam, Richard J Goodyear, Ruishuang Geng, David N Furness, Alexander F J van Aken, Walter Marcotti, Corné J Kros, Guy P Richardson
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19183 (2011)
Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23 (CDH23) are associated with tip links, structures thought to gate the mechanotransducer channels of hair cells in the sensory epithelia of the inner ear. The present
Externí odkaz:
https://doaj.org/article/af12369a59c14234825c2c698e648e37