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Autor:
G M, Ross, I L, Shamovsky, S B, Woo, J I, Post, P N, Vrkljan, G, Lawrance, M, Solc, S M, Dostaler, K E, Neet, R J, Riopelle
Publikováno v:
Journal of neurochemistry. 78(3)
It has recently been shown that transition metal cations Zn2+ and Cu2+ bind to histidine residues of nerve growth factor (NGF) and other neurotrophins (a family of proteins important for neuronal survival) leading to their inactivation. Experimental