Zobrazeno 1 - 10 of 132 pro vyhledávání: '"P N, Plowman"'
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Akademický článek
Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families reveals complex genetic architecture and phenocopies
Autor: Jocelyn N. Plowman, Evanjalina J. Matoy, Lavanya V. Uppala, Samantha B. Draves, Cynthia J. Watson, Bridget A. Sefranek, Mark L. Stacey, Samuel P. Anderson, Michael A. Belshan, Elizabeth E. Blue, Chad D. Huff, Yusi Fu, Holly A.F. Stessman
Publikováno v: HGG Advances, Vol 5, Iss 3, Pp 100306- (2024)
Summary: Approximately 20% of breast cancer cases are attributed to increased family risk, yet variation in BRCA1/2 can only explain 20%–25% of cases. Historically, only single gene or single variant testing were common in at-risk family members, a
Externí odkaz: https://doaj.org/article/c20ab52b19624c2ebea28cfd72751227
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2
Onco-ontogeny recapitulates phylogeny – a consideration
Autor: C. E. Plowman, P. N. Plowman
Publikováno v: Oncogene. 40:1542-1550
Cancers necessarily rely on the (embryologic) fundamental growth patterning genes to serve their uncontrolled growth. Studying a cancer’s behavior, depending on which side of an embryological divide it derives, together with its transcriptome and i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82e60ff95abe917666c929213dce1312
https://doi.org/10.1038/s41388-020-01624-1
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7
Final adult height and body mass index after cure of paediatric Cushing's disease
Autor: Justin H Davies, F. Afshar, M.O. Savage, Ashley B. Grossman, P. N. Plowman, Kate Davies, John P Monson, Helen L Storr, G. M. Besser
OBJECTIVE: Linear growth data after cure of paediatric Cushing's disease (CD) have been reported infrequently. We evaluated final adult height (FH) and body mass index (BMI) in a cohort of paediatric patients treated successfully for CD. PATIENTS AND
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6c773720a63a2127063f02e56a30aa
https://doi.org/10.1111/j.1365-2265.2005.02244.x
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8
The developing role for intensity-modulated radiation therapy (IMRT) in the non-surgical treatment of brain metastases
Autor: E Keggin, A A Edwards, P N Plowman
Publikováno v: The British Journal of Radiology. 83:133-136
Whole brain radiotherapy (WBRT) is the standard non-surgical treatment for brain metastatic disease, but rarely eradicates bulky metastases from most common cancers. Recent literature has demonstrated the safety and efficacy of delivering very high f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704c2e4b3fa4ff0c9182376e8c9d8e6f
https://doi.org/10.1259/bjr/28596848
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9
Gamma knife radiosurgery: a safe and effective salvage treatment for pituitary tumours not controlled despite conventional radiotherapy
Autor: Ashley B. Grossman, P. N. Plowman, Francesca Swords, John R. T. Monson, G. M. Besser, S. L. Chew, W M Drake
Publikováno v: European Journal of Endocrinology. 161:819-828
ObjectiveWe report the use of ‘gamma knife’ (GK) radiosurgery in 25 patients with pituitary adenomas not cured despite conventional therapy, including external beam radiotherapy.Patients and methodsAll patients had previously received conventiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394ea3e97ee724789a7e3ccde6389c81
https://doi.org/10.1530/eje-09-0493
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10
Recent London Improvements in Curative Radiation Therapy for Relevant Early Prostate Cancer
Autor: P. N. Plowman
Publikováno v: Annals of the New York Academy of Sciences. 1138:257-266
Since the advent of PSA screening, the detection of early (organ confined) prostate cancer has improved. Although some indolent cancers in the elderly may be safely watched, the early diagnosis in younger men requires curative treatment. Two exciting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ecd704a5f3183e0609795bf9d8f11a
https://doi.org/10.1196/annals.1414.031
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